19. Clinical Prediction Rule 1
• Jones and Lowes
• Systemic inflammatory response syndrome
(SIRS) present with at least 2 of the following:
– Temperature <36°C or >38°C
– Heart rate >90/min
– Respiratory rate >22/min OR pCO2 <32 mm Hg
on arterial blood gas
– White blood cell count <4000/μL or >12 000/μL
OR >10% immature neutrophils (band forms)
20. Clinical Prediction Rule 2
• Shapiro et al.
• Blood culture indicated if 1 major OR 2 minor of the following:
• Major
• Suspicion of endocarditis
• Temperature >39.4°C
• Indwelling catheter
• Minor
• Temperature 38.3°C-39.3°C
• Age >65 years
• Chills
• Vomiting
• Systolic blood pressure <90 mm Hg
• White blood cell count>18 000/μL
• Creatinine >2 mg/dL (> 177 μmol/L)