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Genetics
          vis-à-vis
Shukravaha Srotas

            Presenter
          Dr.Pallavi.G
        Ist P.G Scholar
Dept of P.G Studies in Ayurveda
           Siddhanta
Govt Ayurveda Medical College
            Mysore
Under the guidance of

Dr.Shreevathsa   M.D (Ayu)     Dr.Shakunthala .G.N          M.D
                             (Ayu)
      Lecturer                       Prof and Head of the Dept


     Dept of P.G Studies in Ayurveda Siddhanta
             Govt Ayurveda Medical College
                     Mysore
Contents
 Introduction
 Beeja, Beeja bhaga, Beeja bhaga
Avayava
 Pathological    manifestations    of
Shukravaha Srotas due to Beeja, Beeja
bhaga , Beeja bhaga avayava dushti
 Human Genome Project
 Genetic Counselling
 Conclusion
 Bibliography
Introduction
• Introduction

  Why is the offspring similar to the parents.

  in many respects yet different from them?

  The riddle has been a subject of

  interest to the minds of philosophers

  since time immemorial.
Life seems to have originated on
  .
earth 2000 million years ago and its
continuation is possible by the unique
activity of reproduction for which the
gametes are held responsible.
       The genetic control of sexual
development is very often called the sex
determination and a direct relationship
was found between chromosomes which
an individual receives and the sex it
develops.
Beeja, Beeja bhaga &
    Beeja bhaga avayava
These      are   identified   as   certain
fundamental entities which are responsible
for reproduction.
This      is a highly evolved concept of
genetics which fortunately simulates with
the contemporary concept of genetics
dealt by Acharya Charaka in Shaareera
Sthana.
This concept has been explained in
Ayurvedic classics with the help of
vikaras such as Varta, Putipraja, Truna
putrika
oÉÏeÉ
 oÉÏeÉ CÌiÉ M×üixlÉqÉåuÉ AÉUÇpÉMåü oÉÏeÉå |

 oÉÏeÉ CÌiÉ zÉÑ¢ü zÉÉåÍhÉiÉå | (cÉ¢ümÉÉÍhÉ)

It may be compared to the genotype which
is a complete set of instructions on how
the body is supposed to be built.

It is the Genetic constitution of an
organism which determines different traits
of an individual such as Eye color, Hair
color, Height, Weight, Body structure,
Facial structures, skin color etc.
oÉÏeÉ pÉÉaÉ
AuÉrÉuÉ oÉÏeÉxrÉ LMüSåzÉÈ (cÉ¢ümÉÉÍhÉ)
oÉÏeÉxrÉ A…¡û mÉëirÉ…¡û ÌlÉuÉïiÉïMüÉå pÉÉaÉÉå oÉÏeÉ pÉÉaÉÈ

It may be compared to a chromosome.

The genomes are the set of chromosomal
complements which are passed on as units
from generation to generation one from
each of the parents.

These carry the hereditary information in
the form of genes.

Thus Beeja bhaga is held responsible for
the expression of different characteristics
of individual and origin of different organs
and tissues of the body.
oÉÏeÉ pÉÉaÉ AuÉrÉuÉ
oÉÏeÉ pÉÉaÉ AuÉrÉuÉ -AuÉrÉuÉAÉUÇpÉMü oÉÏeÉ pÉÉaÉ (aÉÇaÉÉkÉU )

This is the most fundamental entity which can be

grossly compared to a gene.

It is the basic physical and functional unit of

heredity which are mainly responsible for

expression of a particular trait in an individual

that are transmitted from one generation to

another.

These      are   specific    sequences       that   encode

instructions on how to make proteins which in

turn are responsible for the expression of a trait.
rÉxrÉ rÉxrÉ ÌWû A…¡û AuÉrÉuÉxrÉ

oÉÏeÉå oÉÏeÉpÉÉaÉ EmÉiÉmiÉÉå pÉuÉÌiÉ, iÉxrÉ

     iÉxrÉÉ…¡ûÉuÉrÉuÉxrÉ ÌuÉM×üÌiÉÂmÉeÉÉrÉiÉå,

  lÉÉåmÉeÉÉrÉiÉå cÉÉlÉÑmÉiÉÉmÉÉiÉç| cÉ.zÉÉ3/17

This concept holds good for each

and      every       srotas.       Whichever

avayava of beeja bhaga is vitiated

by     the     doshas       the     respective
avayava presents with a disease.
Pathological manifestations of
Shukravaha Srotas due to Beeja
Bhaaga and Beeja bhaga avayava
            dushti
  oÉÏeÉ pÉÉaÉ SÒ̹ –Janma of Vandhya
 ie an infertile male ,
 It may be due to chromosomal
 abnormality       (Structural and
 number), Ex-Turners syndrome,
 Klienefeltors syndrome etc.

  oÉÏeÉ pÉÉaÉ AuÉrÉuÉ SÒ̹ –Janma of
 Putipraja ie a defective progeny
 who is Sterile and impotent along
 with other systemic illness.
 This may be due to defective genes.
oÉÏeÉ pÉÉaÉ AuÉrÉuÉ SÒ̹-
rÉSÉ iuÉxrÉ oÉÏeÉå oÉÏeÉpÉÉaÉÉuÉrÉuÉÈ mÉÑÂwÉMüUÉhÉÉqÉç cÉ zÉUÏU
oÉÏeÉ pÉÉaÉÉlÉÉqÉç LMüSåzÉÈ mÉëSÉåwÉqÉÉmɱiÉå, iÉSÉ mÉÑÂwÉÉM×üÌiÉ
pÉÔÌrɸqÉç AmÉÑÂwÉqÉç iÉ×hÉmÉŅ̃ÉMÇü lÉÉqÉeÉlÉrÉÌiÉ | cÉ.zÉÉ 4/31
Here the vitiation is at the most priliminary level i.e gene
responsible for generation of male sexual characteristics is
affected..


Gene has an attribute to control metabolism at cellular level
that is direct synthesis of enzymes and hormones to
regulate internal chemical environment and produce
optimal conditions for carrying out various cellular
activities and accomplish what is observed in the
phenotype.


It can be compared to set of conditions such as testicular
feminization where in the probable cause may be absence
of enzymes for testosterone synthesis even though the
karyotype is of normal male 46XY .
Sahaja klaibya- genetic and congenital factors
responsible for impotency are included here
Dwireta-This may be compared to Intersex.It
is usually said to be congenital, involving
chromosomal morphologic, genital /gonadal
anamolies such as diversion from typical XX
or XY. Such Individual may have biological
characteristics of both male and female sexes.
Pavanendriya-It may be compared        to
Bilateral anorchia or vanishing testes
syndrome , an extrememly rare disorder
Samskaravhi-Congenital disorders of sperm
transport are rarely due to absence or atresia of
the male ductal system.
Vatika Shanda- Testicular factors may
include genetic defects on the Y chromosome,
testicular dysgenesis syndrome etc.
Human Genome Project
Human Genome Project ( massive international
research project) is an appreciable attempt to
explore the concept of Beeja, Beeja Bhaga,Beeja
Bhaga avayava.
The basic program of this project constitutes
identifying specific phenotypic features ,corelating
them with genotypes and to elucidate the entire
sequence of genes on all the human chromosomes.
Scientists suggest that the genetic key to human
complexity lies not in the gene number but in how
gene parts are used to build different products.
Particular gene sequences have been associated
with numerous diseases and disorders including
breast cancer, muscle disease, deafness , blindness
etc and hence genetic counselling is gaining
importance nowadays so as to tackle such
disorders.
Genetic Counselling
It is the communication process which
deals with the human problems associated
with the occurrence or risk of genetic
disorder in a family..
Couples seek genetic counselling at
different stages- Before marriage, pre-
conceptional period such as in advanced
maternal age, During pregnancy and
reterospectively after the birth of an
offspring afflicted with genetic disorder.
Keeping Ayurvedic principles in view ,
the couple should be instructed beginning
from     the     Vivaha,    followed       by
Garbhadhana upto to the Prasava.
Genetic counselling may aid at different
levels of formation of prakriti
Atulyagotriya vivaaha, and appropriate
age for marriage. Counselling to avoid
Consanguineous        marriage     determines
Shukrashonita prakruti.
Counselling to consume healthy diet Shad
rasa yukta ahara for the proper Growth of
the     foetus    which     will    determine
Maaturahara vihara prakruti- Ex-Excess
of intake of Katu rasa and during pregnancy
will lead to Shukra dushti
Counselling to Avoid garbhopaghaatakara
bhavas will determine Kala garbhashaya
prakruti- ex exposure to ionic radiations
may lead to gene mutations.
Following specific garbhini charya for each
month for healthy growth and development
of the foetus which determines Mahabhuta
vikara prakruti-
Hence genetic counselling         may prove
beneficial in avoiding genetic disorders.
Conclusion
Thus the concept of Beeja Beeja bhaga
and Beeja bhaga avayava is a highly
evolved concept of genetics representing
even the minutest entity of genetics of
contemporary science.

Human genome project is an effort to
unfold       each and every beeja bhaga
avayava responsible for a particular trait
and   thus     benefit   the   society   by
preventing the occurrence of genetic
disorders.
Bibliography

Charaka Samhita

Sushruta Samhita

Comprehensive Textbook of Sexual Medicine- Nilamadhab
Kar, Gopal Chandra Kar, 1st Edition 2005 Jaypee Brothers
New Delhi

An Introduction to Genetics- V.V. Kulashrestha First Edition
2002 Avas Vikas colony Aligarh

Ayurvedline- Sex Medicine Part II
Genetics vis-à-vis Shukravaha Srotas
Genetics vis-à-vis Shukravaha Srotas

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Genetics vis-à-vis Shukravaha Srotas

  • 1. Genetics vis-à-vis Shukravaha Srotas Presenter Dr.Pallavi.G Ist P.G Scholar Dept of P.G Studies in Ayurveda Siddhanta Govt Ayurveda Medical College Mysore
  • 2. Under the guidance of Dr.Shreevathsa M.D (Ayu) Dr.Shakunthala .G.N M.D (Ayu) Lecturer Prof and Head of the Dept Dept of P.G Studies in Ayurveda Siddhanta Govt Ayurveda Medical College Mysore
  • 3. Contents Introduction Beeja, Beeja bhaga, Beeja bhaga Avayava Pathological manifestations of Shukravaha Srotas due to Beeja, Beeja bhaga , Beeja bhaga avayava dushti Human Genome Project Genetic Counselling Conclusion Bibliography
  • 4. Introduction • Introduction Why is the offspring similar to the parents. in many respects yet different from them? The riddle has been a subject of interest to the minds of philosophers since time immemorial.
  • 5. Life seems to have originated on . earth 2000 million years ago and its continuation is possible by the unique activity of reproduction for which the gametes are held responsible. The genetic control of sexual development is very often called the sex determination and a direct relationship was found between chromosomes which an individual receives and the sex it develops.
  • 6. Beeja, Beeja bhaga & Beeja bhaga avayava These are identified as certain fundamental entities which are responsible for reproduction. This is a highly evolved concept of genetics which fortunately simulates with the contemporary concept of genetics dealt by Acharya Charaka in Shaareera Sthana. This concept has been explained in Ayurvedic classics with the help of vikaras such as Varta, Putipraja, Truna putrika
  • 7. oÉÏeÉ oÉÏeÉ CÌiÉ M×üixlÉqÉåuÉ AÉUÇpÉMåü oÉÏeÉå | oÉÏeÉ CÌiÉ zÉÑ¢ü zÉÉåÍhÉiÉå | (cÉ¢ümÉÉÍhÉ) It may be compared to the genotype which is a complete set of instructions on how the body is supposed to be built. It is the Genetic constitution of an organism which determines different traits of an individual such as Eye color, Hair color, Height, Weight, Body structure, Facial structures, skin color etc.
  • 8. oÉÏeÉ pÉÉaÉ AuÉrÉuÉ oÉÏeÉxrÉ LMüSåzÉÈ (cÉ¢ümÉÉÍhÉ) oÉÏeÉxrÉ A…¡û mÉëirÉ…¡û ÌlÉuÉïiÉïMüÉå pÉÉaÉÉå oÉÏeÉ pÉÉaÉÈ It may be compared to a chromosome. The genomes are the set of chromosomal complements which are passed on as units from generation to generation one from each of the parents. These carry the hereditary information in the form of genes. Thus Beeja bhaga is held responsible for the expression of different characteristics of individual and origin of different organs and tissues of the body.
  • 9. oÉÏeÉ pÉÉaÉ AuÉrÉuÉ oÉÏeÉ pÉÉaÉ AuÉrÉuÉ -AuÉrÉuÉAÉUÇpÉMü oÉÏeÉ pÉÉaÉ (aÉÇaÉÉkÉU ) This is the most fundamental entity which can be grossly compared to a gene. It is the basic physical and functional unit of heredity which are mainly responsible for expression of a particular trait in an individual that are transmitted from one generation to another. These are specific sequences that encode instructions on how to make proteins which in turn are responsible for the expression of a trait.
  • 10. rÉxrÉ rÉxrÉ ÌWû A…¡û AuÉrÉuÉxrÉ oÉÏeÉå oÉÏeÉpÉÉaÉ EmÉiÉmiÉÉå pÉuÉÌiÉ, iÉxrÉ iÉxrÉÉ…¡ûÉuÉrÉuÉxrÉ ÌuÉM×üÌiÉÂmÉeÉÉrÉiÉå, lÉÉåmÉeÉÉrÉiÉå cÉÉlÉÑmÉiÉÉmÉÉiÉç| cÉ.zÉÉ3/17 This concept holds good for each and every srotas. Whichever avayava of beeja bhaga is vitiated by the doshas the respective avayava presents with a disease.
  • 11. Pathological manifestations of Shukravaha Srotas due to Beeja Bhaaga and Beeja bhaga avayava dushti oÉÏeÉ pÉÉaÉ SÒ̹ –Janma of Vandhya ie an infertile male , It may be due to chromosomal abnormality (Structural and number), Ex-Turners syndrome, Klienefeltors syndrome etc. oÉÏeÉ pÉÉaÉ AuÉrÉuÉ SÒ̹ –Janma of Putipraja ie a defective progeny who is Sterile and impotent along with other systemic illness. This may be due to defective genes.
  • 12. oÉÏeÉ pÉÉaÉ AuÉrÉuÉ SÒ̹- rÉSÉ iuÉxrÉ oÉÏeÉå oÉÏeÉpÉÉaÉÉuÉrÉuÉÈ mÉÑÂwÉMüUÉhÉÉqÉç cÉ zÉUÏU oÉÏeÉ pÉÉaÉÉlÉÉqÉç LMüSåzÉÈ mÉëSÉåwÉqÉÉmɱiÉå, iÉSÉ mÉÑÂwÉÉM×üÌiÉ pÉÔÌrɸqÉç AmÉÑÂwÉqÉç iÉ×hÉmÉŅ̃ÉMÇü lÉÉqÉeÉlÉrÉÌiÉ | cÉ.zÉÉ 4/31 Here the vitiation is at the most priliminary level i.e gene responsible for generation of male sexual characteristics is affected.. Gene has an attribute to control metabolism at cellular level that is direct synthesis of enzymes and hormones to regulate internal chemical environment and produce optimal conditions for carrying out various cellular activities and accomplish what is observed in the phenotype. It can be compared to set of conditions such as testicular feminization where in the probable cause may be absence of enzymes for testosterone synthesis even though the karyotype is of normal male 46XY .
  • 13. Sahaja klaibya- genetic and congenital factors responsible for impotency are included here Dwireta-This may be compared to Intersex.It is usually said to be congenital, involving chromosomal morphologic, genital /gonadal anamolies such as diversion from typical XX or XY. Such Individual may have biological characteristics of both male and female sexes. Pavanendriya-It may be compared to Bilateral anorchia or vanishing testes syndrome , an extrememly rare disorder Samskaravhi-Congenital disorders of sperm transport are rarely due to absence or atresia of the male ductal system. Vatika Shanda- Testicular factors may include genetic defects on the Y chromosome, testicular dysgenesis syndrome etc.
  • 14. Human Genome Project Human Genome Project ( massive international research project) is an appreciable attempt to explore the concept of Beeja, Beeja Bhaga,Beeja Bhaga avayava. The basic program of this project constitutes identifying specific phenotypic features ,corelating them with genotypes and to elucidate the entire sequence of genes on all the human chromosomes. Scientists suggest that the genetic key to human complexity lies not in the gene number but in how gene parts are used to build different products. Particular gene sequences have been associated with numerous diseases and disorders including breast cancer, muscle disease, deafness , blindness etc and hence genetic counselling is gaining importance nowadays so as to tackle such disorders.
  • 15. Genetic Counselling It is the communication process which deals with the human problems associated with the occurrence or risk of genetic disorder in a family.. Couples seek genetic counselling at different stages- Before marriage, pre- conceptional period such as in advanced maternal age, During pregnancy and reterospectively after the birth of an offspring afflicted with genetic disorder. Keeping Ayurvedic principles in view , the couple should be instructed beginning from the Vivaha, followed by Garbhadhana upto to the Prasava. Genetic counselling may aid at different levels of formation of prakriti
  • 16. Atulyagotriya vivaaha, and appropriate age for marriage. Counselling to avoid Consanguineous marriage determines Shukrashonita prakruti. Counselling to consume healthy diet Shad rasa yukta ahara for the proper Growth of the foetus which will determine Maaturahara vihara prakruti- Ex-Excess of intake of Katu rasa and during pregnancy will lead to Shukra dushti Counselling to Avoid garbhopaghaatakara bhavas will determine Kala garbhashaya prakruti- ex exposure to ionic radiations may lead to gene mutations. Following specific garbhini charya for each month for healthy growth and development of the foetus which determines Mahabhuta vikara prakruti- Hence genetic counselling may prove beneficial in avoiding genetic disorders.
  • 17. Conclusion Thus the concept of Beeja Beeja bhaga and Beeja bhaga avayava is a highly evolved concept of genetics representing even the minutest entity of genetics of contemporary science. Human genome project is an effort to unfold each and every beeja bhaga avayava responsible for a particular trait and thus benefit the society by preventing the occurrence of genetic disorders.
  • 18. Bibliography Charaka Samhita Sushruta Samhita Comprehensive Textbook of Sexual Medicine- Nilamadhab Kar, Gopal Chandra Kar, 1st Edition 2005 Jaypee Brothers New Delhi An Introduction to Genetics- V.V. Kulashrestha First Edition 2002 Avas Vikas colony Aligarh Ayurvedline- Sex Medicine Part II