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vitamin A and its role of vision in the dim light.pdf
- 1. All trans retinal Retinal reductase All trans retinol Closure of Na+ channels of outer segment Intracellular potential becomes more –ve (hyperpolarization) Initiation nerve impulse from receptors of retina to optic nerve to brain Biochemistry of special sense modules MEQ BY/Mohamed Ali Dr /Mohamed Ali
- 2. Rhodopsin Bathorhodopsin Light energy Lumirhodopsin Metarhodopsin 1 Metarhodopsin 2 All trans retinal Opsin Retinal reductase All trans retinol In liver Isomerase 11-cis retinol Retinal oxidase 11-cis retinal Activation of transducin Activation of c-GMP phosphodiesterase Hydrolysis of c-GMP → ↓ c-GMP & ↑ GMP Closure of Na+ channels of outer segment Intracellular potential becomes more –ve (hyperpolarization) Initiation nerve impulse from receptors of retina to optic nerve to brain Explain role of vitamin A in vision Visual cycle MEQ By/ Mohamed Ali