SlideShare una empresa de Scribd logo
1 de 36
Descargar para leer sin conexión
CerebellumCerebellum ExternalExternal
ConfigurationsConfigurations
CerebellumCerebellum ExternalExternal
ConfigurationsConfigurations
- located in- located in posterior cranial fossaposterior cranial fossa
- tentorium cerebelli (cerebrum), 4th ventricle (brain stem)- tentorium cerebelli (cerebrum), 4th ventricle (brain stem)
- communicate with other structure via- communicate with other structure via
superior, middle, and inferior cerebellar pedunclesuperior, middle, and inferior cerebellar peduncle
-- longitudinal divisionlongitudinal division
Vermis, Paravermal Region, Cerebellar HemisphereVermis, Paravermal Region, Cerebellar Hemisphere
-- transverse divisiontransverse division
Anterior LobeAnterior Lobe
------------------------ primary fissureprimary fissure
Posterior LobePosterior Lobe
------------------------ posterolateral fissureposterolateral fissure
Flocculonodular LobeFlocculonodular Lobe
Subdivision ofSubdivision of Flocculonodular LobeFlocculonodular Lobe
Nodulus FlocculusNodulus Flocculus
Subdivision ofSubdivision of Anterior LobeAnterior Lobe
Vermis HemisphereVermis Hemisphere
LingulaLingula
Central LobuleCentral Lobule Ala Central LobuleAla Central Lobule
postcentral fissurepostcentral fissure
CulmenCulmen Quadriangular LobuleQuadriangular Lobule
CerebellumCerebellum ExternalExternal
ConfigurationsConfigurations
CerebellumCerebellum ExternalExternal
ConfigurationsConfigurations
Subdivision ofSubdivision of Posterior LobePosterior Lobe
Vermis HemisphereVermis Hemisphere
DecliveDeclive Simple LobuleSimple Lobule
postcentral fissurepostcentral fissure
FoliumFolium Superior Semilunar LobuleSuperior Semilunar Lobule
horizontal fissurehorizontal fissure
Inferior Semilunar LobuleInferior Semilunar Lobule
TuberTuber
Gracile LobuleGracile Lobule
prepyramidal fissureprepyramidal fissure
PyramisPyramis Biventer LobuleBiventer Lobule
secondary fissuresecondary fissure
UvulaUvula TonsilTonsil
CerebellumCerebellum ExternalExternal
ConfigurationsConfigurations
CerebellumCerebellum ExternalExternal
ConfigurationsConfigurations
Cerebellum by prc (1)
Cerebellar CortexCerebellar Cortex
Molecular LayerMolecular Layer
Purkinje Cell LayerPurkinje Cell Layer
Granular LayerGranular Layer
Corpus Medullare (Medullary Center)Corpus Medullare (Medullary Center)
Deep Cerebellar NucleiDeep Cerebellar Nuclei
Fastigial NucleiFastigial Nuclei
Nucleus InterpositusNucleus Interpositus
Emboliform NucleusEmboliform Nucleus
Globose NucleusGlobose Nucleus
Dentate NucleusDentate Nucleus
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
1. fastigial1. fastigial
nucleusnucleus
2. globose2. globose
nucleusnucleus
3. emboliform3. emboliform
nucleusnucleus
4. dentate4. dentate
nucleusnucleus
Deep NucleiDeep Nuclei
Cerebellar CortexCerebellar Cortex
I. Molecular LayerI. Molecular Layer
Stellate CellStellate Cell --- taurine (inhibitory)--- taurine (inhibitory)
afferent:afferent: parallel fiberparallel fiber
efferent: Purkinje cell dendriteefferent: Purkinje cell dendrite
Basket CellBasket Cell ---- GABA (inhibitory)---- GABA (inhibitory)
afferent:afferent: parallel fiberparallel fiber
efferent: Purkinje cell somaefferent: Purkinje cell soma
Parallel FiberParallel Fiber
granule cell axongranule cell axon
Purkinje Cell DendritePurkinje Cell Dendrite
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
Cerebellar CortexCerebellar Cortex
II. Purkinje Cell LayerII. Purkinje Cell Layer
Purkinje CellPurkinje Cell
-- 15,000,000 in number-- 15,000,000 in number
-- GABA (inhibitory)-- GABA (inhibitory)
afferent:afferent: parallel fiberparallel fiber
climbing fiberclimbing fiber
stellate cellstellate cell
basket cellbasket cell
efferent:efferent: deep cortical nucleideep cortical nuclei
Bergman’s glial cellBergman’s glial cell
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
Cerebellar CortexCerebellar Cortex
III. Granular LayerIII. Granular Layer
Granular CellGranular Cell
-- 50,000,000,000 in number-- 50,000,000,000 in number
-- glutamic acid (excitatory)-- glutamic acid (excitatory)
afferent:afferent: mossy fibermossy fiber
efferent:efferent: Purkinje cell dendritePurkinje cell dendrite
basket cell, stellate cellbasket cell, stellate cell
Golgi cellGolgi cell
Golgi CellGolgi Cell
-- GABA (inhibitory)-- GABA (inhibitory)
afferent: parallel fiber, mossy fiber rosetteafferent: parallel fiber, mossy fiber rosette
efferent: granule cell dendriteefferent: granule cell dendrite
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
1. Purkinje cell
2. granule cell
3. basket cell
4. Golgi cell
5. stellate cell
6. climbing fiber
7. mossy fiber
8. parallel fiber
9. inferior olivary
nucleus
10. deep cerebellar
nuclei
Cerebellum by prc (1)
Synaptic GlomerulusSynaptic Glomerulus
Afferent terminals on granular layerAfferent terminals on granular layer
 Mossy Fiber RosetteMossy Fiber Rosette
-- afferent fibers except-- afferent fibers except
inferior olivary inputinferior olivary input
-- 2/3 of medullary center-- 2/3 of medullary center
 Granular Cell DendriteGranular Cell Dendrite
-- main afferent input-- main afferent input
 Golgi Cell AxonGolgi Cell Axon
-- synapse on granule cell dendrite-- synapse on granule cell dendrite
-- GABA (inhibitory)-- GABA (inhibitory)
-- Surrounded bySurrounded by AstrocyteAstrocyte Foot ProcessFoot Process
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
CerebellumCerebellum InternalInternal
ConfigurationsConfigurations
Synaptic GlomerulusSynaptic Glomerulus
Classification by Phylogenetic and Ontogenic DevelopmentClassification by Phylogenetic and Ontogenic Development
ArchicerebellumArchicerebellum
PaleocerebllumPaleocerebllum
NeocerebellumNeocerebellum
Classification by Afferent ConnectionClassification by Afferent Connection
VestibulocerebellumVestibulocerebellum
SpinocerebellumSpinocerebellum
PontocerebellumPontocerebellum
Classification by Efferent ConnectionClassification by Efferent Connection
VermisVermis
Paravermal RegionParavermal Region
Cerebellar HemisphereCerebellar Hemisphere
CerebellumCerebellum
ClassificationsClassifications
CerebellumCerebellum
ClassificationsClassifications
Archicerebellum
(nodulus)
Archicerebellum
(flocculus)
Paleocerebellum
Neocerebellum
Spinocerebellum
Pontocerebellum
Vestibulocerebellum
Afferent ConnectionsAfferent Connections (1):(1):
1. Inferior Cerebellar Peduncle1. Inferior Cerebellar Peduncle
Restiform BodyRestiform Body
Posterior Spinocerebellar TractPosterior Spinocerebellar Tract
Olivocerebellar tractOlivocerebellar tract
Cuneocerebellar TractCuneocerebellar Tract
Reticulocerebellar TractReticulocerebellar Tract
Juxtarestiform BodyJuxtarestiform Body
Vestibulocerebellar TractVestibulocerebellar Tract
Primary Vestyibular FiberPrimary Vestyibular Fiber
CerebellumCerebellum
ConnectionsConnections
CerebellumCerebellum
ConnectionsConnections
Afferent ConnectionsAfferent Connections (2):(2):
2. Middle Cerebellar Peduncle2. Middle Cerebellar Peduncle
Pontocerebellar fiberPontocerebellar fiber
Corticopontocerebellar FiberCorticopontocerebellar Fiber
Reticulocerebellar FiberReticulocerebellar Fiber
3. Superior Cerebellar Peduncle3. Superior Cerebellar Peduncle
Anterior Spinocerebellar TractAnterior Spinocerebellar Tract
Cerulocerebellar fiberCerulocerebellar fiber
Raphecerebellar fiberRaphecerebellar fiber
Rubrocerebellar fiberRubrocerebellar fiber
Hypothalamocerebellar fiberHypothalamocerebellar fiber
CerebellumCerebellum
ConnectionsConnections
CerebellumCerebellum
ConnectionsConnections
Efferent ConnectionsEfferent Connections ::
1. Superior Cerebellar Peduncle1. Superior Cerebellar Peduncle
Cerebellothalamic fiberCerebellothalamic fiber
- from 3 deep nuclei to VPLo, VLc, CL- from 3 deep nuclei to VPLo, VLc, CL
Cerebellorubral fiberCerebellorubral fiber
- from nucleus interpositus- from nucleus interpositus
and dentate nucleusand dentate nucleus
ascending portion ofascending portion of
uncinate fasciculus of Russelluncinate fasciculus of Russell
2. Inferior Cerebellar Peduncle2. Inferior Cerebellar Peduncle
Fastigiovestibular fiberFastigiovestibular fiber
descending portion ofdescending portion of
uncinate fasciculus of Russelluncinate fasciculus of Russell
CerebellumCerebellum
ConnectionsConnections
CerebellumCerebellum
ConnectionsConnections
MLFMLF
Main Connections of the VestibulocerebellumMain Connections of the VestibulocerebellumMain Connections of the VestibulocerebellumMain Connections of the Vestibulocerebellum
lower motor neuronlower motor neuron
LMNLMN
vestibulospinal tractvestibulospinal tract
FASTIGIALFASTIGIAL
NUCLEUSNUCLEUS
VestibularVestibular
OrganOrgan
FloculonodularFloculonodular
LobeLobe
VermisVermis
ARCHICEREBELLUMARCHICEREBELLUM
VESTIBULAR NUCLEUSVESTIBULAR NUCLEUS
Main Connections of the PaleocerebellumMain Connections of the PaleocerebellumMain Connections of the PaleocerebellumMain Connections of the Paleocerebellum
lower motor neuronlower motor neuron
SPINAL CORDSPINAL CORD
rubrospinalrubrospinal
tracttract
NUCLEUSNUCLEUS
INTERPOSITUSINTERPOSITUS
InferiorInferior
OlivryOlivry
NucleusNucleus
ANTERIORANTERIOR
LOBELOBE
PARAVERMALPARAVERMAL
ZONEZONE
PALEOCEREBELLUMPALEOCEREBELLUM
REDRED
NUCLEUSNUCLEUS
spinocerebellarspinocerebellar
tracttract
CEREBRALCEREBRAL
CORTEXCORTEX
CEREBRALCEREBRAL
CORTEXCORTEX
DENTATEDENTATE
NUCLEUSNUCLEUS
DENTATEDENTATE
NUCLEUSNUCLEUS
Main Connections of the NeocerebellumMain Connections of the NeocerebellumMain Connections of the NeocerebellumMain Connections of the Neocerebellum
lower motor neuronlower motor neuron
LMNLMN
pyramidalpyramidal
tracttract POSTERIORPOSTERIOR
LOBELOBE
CEREBELLARCEREBELLAR
HEMISPHEREHEMISPHERE
POSTERIORPOSTERIOR
LOBELOBE
CEREBELLARCEREBELLAR
HEMISPHEREHEMISPHERE
THALAMUSTHALAMUSTHALAMUSTHALAMUS
NEOCEREBELLUMNEOCEREBELLUM
PontinePontine
NucleusNucleus
PontinePontine
NucleusNucleus
upper motor neuronupper motor neuron
UMNUMN
upper motor neuronupper motor neuron
UMNUMN
BASALBASAL
GANGLIAGANGLIA
BASALBASAL
GANGLIAGANGLIA
Pyramidal Tract and Associated CircuitsPyramidal Tract and Associated CircuitsPyramidal Tract and Associated CircuitsPyramidal Tract and Associated Circuits
lower motor neuronlower motor neuron
UMNUMN
lower motor neuronlower motor neuron
UMNUMN
pyramidal tractpyramidal tract
CerebellumCerebellumCerebellumCerebellum
Reticular
Formation
Reticular
Formation
CEREBELLUMCEREBELLUM
Cerebellum and Automatic Motor ControlCerebellum and Automatic Motor ControlCerebellum and Automatic Motor ControlCerebellum and Automatic Motor Control
Lower Motor Neuron (LMN)Lower Motor Neuron (LMN)Lower Motor Neuron (LMN)Lower Motor Neuron (LMN)
Motor CortexMotor Cortex
Red NucleusRed Nucleus
Vestibular
Nucleus
Vestibular
Nucleus
ProprioceptorsProprioceptorsProprioceptorsProprioceptors
Corticonuclear ConnectionsCorticonuclear Connections
A zone ---------- fastigial nucleusA zone ---------- fastigial nucleus
medial vestibular nucleusmedial vestibular nucleus
B zone ---------- lateral vestibular nucleusB zone ---------- lateral vestibular nucleus
CC11, C, C33 zone --- emboliform nucleuszone --- emboliform nucleus
CC22 ---------------- globose nucleus---------------- globose nucleus
DD11 ---------------- parvocellular portion of dentate nucleus---------------- parvocellular portion of dentate nucleus
DD22 ---------------- magnocellular portion of dentate nucleus---------------- magnocellular portion of dentate nucleus
CerebellumCerebellum
ConnectionsConnections
CerebellumCerebellum
ConnectionsConnections
1. vermis1. vermis
2. paravermal2. paravermal regionregion
3. cerebella hemisphere3. cerebella hemisphere
4. nodulus4. nodulus
5. flocculus5. flocculus
6. fastigial6. fastigial nucleusnucleus
7. globose7. globose nucleusnucleus
8. emboliform8. emboliform nucleusnucleus
9. dentate9. dentate nucleusnucleus
10. medial vestibular10. medial vestibular
nucleusnucleus
11. lateral vestibular11. lateral vestibular
nucleusnucleus
Olivocerebellar ConnectionsOlivocerebellar Connections
Caudal portion ofCaudal portion of
medial and dorsal accessory olivary nucleusmedial and dorsal accessory olivary nucleus
----------------- vermis of cerebellar cortex (A and B)----------------- vermis of cerebellar cortex (A and B)
fastigial nucleusfastigial nucleus
vestibular nucleusvestibular nucleus
Rostral portion ofRostral portion of
medial and dorsal accessory olivary nucleusmedial and dorsal accessory olivary nucleus
----------------- paravermal region (C----------------- paravermal region (C11, C, C22, C, C33))
nucleus interpositusnucleus interpositus
Principal Inferior Olivary NucleusPrincipal Inferior Olivary Nucleus
----------------- cerebellar hemisphere (D----------------- cerebellar hemisphere (D11, D, D22))
dentate nucleusdentate nucleus
CerebellumCerebellum
ConnectionsConnections
CerebellumCerebellum
ConnectionsConnections
medial and dorsal accessory olivary nucleusmedial and dorsal accessory olivary nucleus
caudal portioncaudal portion rostral portionrostral portion PrincipalPrincipal
Inferior OlivaryInferior Olivary
NucleusNucleus
CerebellumCerebellum
FunctionFunction
CerebellumCerebellum
FunctionFunction
 Maintenance of EquilibriumMaintenance of Equilibrium
- balance, posture, eye movement- balance, posture, eye movement
 Coordination of half-automatic movement ofCoordination of half-automatic movement of
walking and posture maintenacewalking and posture maintenace
- posture, gait- posture, gait
 Adjustment of Muscle ToneAdjustment of Muscle Tone
 Motor Leaning – Motor SkillsMotor Leaning – Motor Skills
 Cognitive FunctionCognitive Function
BalanceBalance
Motor SkillMotor Skill
Pablo CasalsPablo Casals
CerebellumCerebellum ClinicalClinical
SyndromesSyndromes
CerebellumCerebellum ClinicalClinical
SyndromesSyndromes
AtaxiaAtaxia: incoordination of movement: incoordination of movement
- decomposition of movement- decomposition of movement
- dysmetria, past-pointing- dysmetria, past-pointing
- dysdiadochokinesia- dysdiadochokinesia
- rebound phenomenon of Holmes- rebound phenomenon of Holmes
- gait ataxia, truncal ataxia, titubation- gait ataxia, truncal ataxia, titubation
IntentionIntention TremorTremor
Hypotonia,Hypotonia, NystagmusNystagmus
Archicerebellar LesionArchicerebellar Lesion: medulloblastoma: medulloblastoma
Paleocerebellar LesionPaleocerebellar Lesion: gait disturbance: gait disturbance
Neocerebellar LesionNeocerebellar Lesion: hypotonia, ataxia, tremor: hypotonia, ataxia, tremor
PosturePosture
Gait – AtaxiaGait – Ataxia
TremorTremor
CerebellarCerebellar
AtaxiaAtaxia
Ataxic gait andAtaxic gait and
position:position:
Left cerebellar tumorLeft cerebellar tumor
a. Sways to the right ina. Sways to the right in
standing positionstanding position
b. Steady on theb. Steady on the
right legright leg
c. Unsteady on thec. Unsteady on the
left legleft leg
d. ataxic gaitd. ataxic gait
a b c
d
Cerebellar tumors onCerebellar tumors on vermisvermis
- Truncal Ataxia- Truncal Ataxia
- Frequent Falling- Frequent Falling
The child in this picture:The child in this picture:
- would not try to stand- would not try to stand
unsupportedunsupported
- would not let go of the bed rail- would not let go of the bed rail
if she was stood on the floor.if she was stood on the floor.
CerebellarCerebellar
MedulloblastomaMedulloblastoma
Cerebellum by prc (1)

Más contenido relacionado

La actualidad más candente

Animated interactive cerebellum connections
Animated interactive cerebellum connectionsAnimated interactive cerebellum connections
Animated interactive cerebellum connectionsSanjoy Sanyal
 
Spinal cord... information
Spinal cord... informationSpinal cord... information
Spinal cord... informationQurba Kiran
 
Embryology development of central nervous system
Embryology   development of central nervous systemEmbryology   development of central nervous system
Embryology development of central nervous systemMBBS IMS MSU
 
Cerebellum by dr.gourav thakre 20 03-2012
Cerebellum by dr.gourav thakre 20 03-2012Cerebellum by dr.gourav thakre 20 03-2012
Cerebellum by dr.gourav thakre 20 03-2012Gourav Thakre
 
Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...
Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...
Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...ssuser6e679b
 
Cns path congenital, edema
Cns path congenital, edemaCns path congenital, edema
Cns path congenital, edemaraj kumar
 
Anatomy of cerebellum
Anatomy of cerebellumAnatomy of cerebellum
Anatomy of cerebellumMBBS IMS MSU
 
The cerebellum demo
The cerebellum demoThe cerebellum demo
The cerebellum demofarhan_aq91
 
презентация Accesorius
презентация Accesoriusпрезентация Accesorius
презентация AccesoriusAjaindu Shrivastava
 
Neural crest cell /certified fixed orthodontic courses by Indian dental academy
Neural crest cell /certified fixed orthodontic courses by Indian dental academy Neural crest cell /certified fixed orthodontic courses by Indian dental academy
Neural crest cell /certified fixed orthodontic courses by Indian dental academy Indian dental academy
 

La actualidad más candente (20)

Animated interactive cerebellum connections
Animated interactive cerebellum connectionsAnimated interactive cerebellum connections
Animated interactive cerebellum connections
 
Spinal cord... information
Spinal cord... informationSpinal cord... information
Spinal cord... information
 
Embryology development of central nervous system
Embryology   development of central nervous systemEmbryology   development of central nervous system
Embryology development of central nervous system
 
Anatomy of Cerebellum(Part- 2)
Anatomy of Cerebellum(Part- 2)Anatomy of Cerebellum(Part- 2)
Anatomy of Cerebellum(Part- 2)
 
1
11
1
 
Cerebellum by dr.gourav thakre 20 03-2012
Cerebellum by dr.gourav thakre 20 03-2012Cerebellum by dr.gourav thakre 20 03-2012
Cerebellum by dr.gourav thakre 20 03-2012
 
Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...
Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...
Anatomy of Cerebellum professor dr saeed abuel makareem _ Relevant Connection...
 
Cerebellum
CerebellumCerebellum
Cerebellum
 
Cns path congenital, edema
Cns path congenital, edemaCns path congenital, edema
Cns path congenital, edema
 
Anatomy of cerebellum
Anatomy of cerebellumAnatomy of cerebellum
Anatomy of cerebellum
 
The cerebellum demo
The cerebellum demoThe cerebellum demo
The cerebellum demo
 
Cerebral cortex
Cerebral cortexCerebral cortex
Cerebral cortex
 
Cerebellum surgical anatomy
Cerebellum surgical anatomyCerebellum surgical anatomy
Cerebellum surgical anatomy
 
презентация Opticus
презентация Opticusпрезентация Opticus
презентация Opticus
 
презентация Accesorius
презентация Accesoriusпрезентация Accesorius
презентация Accesorius
 
Visual pathway ppt
Visual pathway pptVisual pathway ppt
Visual pathway ppt
 
Embryology Of Brain
Embryology Of BrainEmbryology Of Brain
Embryology Of Brain
 
cerebellum
cerebellum cerebellum
cerebellum
 
Neural crest cell /certified fixed orthodontic courses by Indian dental academy
Neural crest cell /certified fixed orthodontic courses by Indian dental academy Neural crest cell /certified fixed orthodontic courses by Indian dental academy
Neural crest cell /certified fixed orthodontic courses by Indian dental academy
 
Cerebellum
CerebellumCerebellum
Cerebellum
 

Similar a Cerebellum by prc (1)

Cerebelum ventr. IV
Cerebelum ventr. IVCerebelum ventr. IV
Cerebelum ventr. IVdr Šarac
 
Limbic system
Limbic systemLimbic system
Limbic systemdocajoy
 
Radiological anatomy of the brain
Radiological anatomy of the brainRadiological anatomy of the brain
Radiological anatomy of the brainMohamed Shaaban
 
Cerebellum Physiology
Cerebellum  PhysiologyCerebellum  Physiology
Cerebellum PhysiologyRaghu Veer
 
Cerebellum-Connections and Functions
Cerebellum-Connections and FunctionsCerebellum-Connections and Functions
Cerebellum-Connections and FunctionsRanadhi Das
 
Cerebellum 2010
Cerebellum 2010Cerebellum 2010
Cerebellum 2010PS Deb
 
Cerebrum and sulcus and gyri and their functional areas
Cerebrum and sulcus and gyri and their functional areasCerebrum and sulcus and gyri and their functional areas
Cerebrum and sulcus and gyri and their functional areasOmpriyaS
 
CEREBELLUM- with clinical and radiology
CEREBELLUM- with clinical and radiologyCEREBELLUM- with clinical and radiology
CEREBELLUM- with clinical and radiologylalit yadav
 
Gross structure of the brain
Gross structure of the brainGross structure of the brain
Gross structure of the brainHatesh Mahtani
 
cerebellum final ppt.ppt
cerebellum final ppt.pptcerebellum final ppt.ppt
cerebellum final ppt.pptnitesh agrawal
 

Similar a Cerebellum by prc (1) (20)

Ataxia cerebelosa
Ataxia cerebelosaAtaxia cerebelosa
Ataxia cerebelosa
 
Cerebelum ventr. IV
Cerebelum ventr. IVCerebelum ventr. IV
Cerebelum ventr. IV
 
Cerebral cortex
Cerebral cortexCerebral cortex
Cerebral cortex
 
Limbic system
Limbic systemLimbic system
Limbic system
 
Cbr cortex
Cbr cortexCbr cortex
Cbr cortex
 
Lect -brainstem
Lect -brainstemLect -brainstem
Lect -brainstem
 
Cerebellum
CerebellumCerebellum
Cerebellum
 
Radiological anatomy of the brain
Radiological anatomy of the brainRadiological anatomy of the brain
Radiological anatomy of the brain
 
Radiological anatomy of the brain
Radiological anatomy of the brainRadiological anatomy of the brain
Radiological anatomy of the brain
 
The cerebellum
The cerebellumThe cerebellum
The cerebellum
 
Orbital anatomy
Orbital anatomyOrbital anatomy
Orbital anatomy
 
Cerebellum Physiology
Cerebellum  PhysiologyCerebellum  Physiology
Cerebellum Physiology
 
Cerebellum-Connections and Functions
Cerebellum-Connections and FunctionsCerebellum-Connections and Functions
Cerebellum-Connections and Functions
 
Cerebellum 2010
Cerebellum 2010Cerebellum 2010
Cerebellum 2010
 
CORE NERVOUS SYSTEM AND OPTION A
CORE NERVOUS SYSTEM AND OPTION ACORE NERVOUS SYSTEM AND OPTION A
CORE NERVOUS SYSTEM AND OPTION A
 
Cerebrum and sulcus and gyri and their functional areas
Cerebrum and sulcus and gyri and their functional areasCerebrum and sulcus and gyri and their functional areas
Cerebrum and sulcus and gyri and their functional areas
 
CEREBELLUM- with clinical and radiology
CEREBELLUM- with clinical and radiologyCEREBELLUM- with clinical and radiology
CEREBELLUM- with clinical and radiology
 
Gross structure of the brain
Gross structure of the brainGross structure of the brain
Gross structure of the brain
 
cerebellum final ppt.ppt
cerebellum final ppt.pptcerebellum final ppt.ppt
cerebellum final ppt.ppt
 
Cerebellum
CerebellumCerebellum
Cerebellum
 

Más de prema5252

Birth control
Birth controlBirth control
Birth controlprema5252
 
21 spinal cord tracts iby prc
21 spinal cord tracts iby prc21 spinal cord tracts iby prc
21 spinal cord tracts iby prcprema5252
 
Heart sound by p r choudhary
Heart sound by p r choudharyHeart sound by p r choudhary
Heart sound by p r choudharyprema5252
 
1.blood group
1.blood group1.blood group
1.blood groupprema5252
 

Más de prema5252 (7)

Birth control
Birth controlBirth control
Birth control
 
21 spinal cord tracts iby prc
21 spinal cord tracts iby prc21 spinal cord tracts iby prc
21 spinal cord tracts iby prc
 
Heart sound by p r choudhary
Heart sound by p r choudharyHeart sound by p r choudhary
Heart sound by p r choudhary
 
Eeg by prc
Eeg by prcEeg by prc
Eeg by prc
 
Eeg by prc
Eeg by prcEeg by prc
Eeg by prc
 
1.blood group
1.blood group1.blood group
1.blood group
 
201 urinary
201 urinary201 urinary
201 urinary
 

Último

001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...
001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...
001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...marwaahmad357
 
MARSILEA notes in detail for II year Botany.ppt
MARSILEA  notes in detail for II year Botany.pptMARSILEA  notes in detail for II year Botany.ppt
MARSILEA notes in detail for II year Botany.pptaigil2
 
Controlling Parameters of Carbonate platform Environment
Controlling Parameters of Carbonate platform EnvironmentControlling Parameters of Carbonate platform Environment
Controlling Parameters of Carbonate platform EnvironmentRahulVishwakarma71547
 
Principles & Formulation of Hair Care Products
Principles & Formulation of Hair Care  ProductsPrinciples & Formulation of Hair Care  Products
Principles & Formulation of Hair Care Productspurwaborkar@gmail.com
 
Pests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdf
Pests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdfPests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdf
Pests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdfPirithiRaju
 
Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...
Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...
Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...Sérgio Sacani
 
Main Exam Applied biochemistry final year
Main Exam Applied biochemistry final yearMain Exam Applied biochemistry final year
Main Exam Applied biochemistry final yearmarwaahmad357
 
PSP3 employability assessment form .docx
PSP3 employability assessment form .docxPSP3 employability assessment form .docx
PSP3 employability assessment form .docxmarwaahmad357
 
Lehninger_Chapter 17_Fatty acid Oxid.ppt
Lehninger_Chapter 17_Fatty acid Oxid.pptLehninger_Chapter 17_Fatty acid Oxid.ppt
Lehninger_Chapter 17_Fatty acid Oxid.pptSachin Teotia
 
biosynthesis of the cell wall and antibiotics
biosynthesis of the cell wall and antibioticsbiosynthesis of the cell wall and antibiotics
biosynthesis of the cell wall and antibioticsSafaFallah
 
Basic Concepts in Pharmacology in molecular .pptx
Basic Concepts in Pharmacology in molecular  .pptxBasic Concepts in Pharmacology in molecular  .pptx
Basic Concepts in Pharmacology in molecular .pptxVijayaKumarR28
 
soft skills question paper set for bba ca
soft skills question paper set for bba casoft skills question paper set for bba ca
soft skills question paper set for bba caohsadfeeling
 
MARKER ASSISTED SELECTION IN CROP IMPROVEMENT
MARKER ASSISTED SELECTION IN CROP IMPROVEMENTMARKER ASSISTED SELECTION IN CROP IMPROVEMENT
MARKER ASSISTED SELECTION IN CROP IMPROVEMENTjipexe1248
 
Pests of ragi_Identification, Binomics_Dr.UPR
Pests of ragi_Identification, Binomics_Dr.UPRPests of ragi_Identification, Binomics_Dr.UPR
Pests of ragi_Identification, Binomics_Dr.UPRPirithiRaju
 
Exploration Method’s in Archaeological Studies & Research
Exploration Method’s in Archaeological Studies & ResearchExploration Method’s in Archaeological Studies & Research
Exploration Method’s in Archaeological Studies & ResearchPrachya Adhyayan
 
TORSION IN GASTROPODS- Anatomical event (Zoology)
TORSION IN GASTROPODS- Anatomical event (Zoology)TORSION IN GASTROPODS- Anatomical event (Zoology)
TORSION IN GASTROPODS- Anatomical event (Zoology)chatterjeesoumili50
 
CW marking grid Analytical BS - M Ahmad.docx
CW  marking grid Analytical BS - M Ahmad.docxCW  marking grid Analytical BS - M Ahmad.docx
CW marking grid Analytical BS - M Ahmad.docxmarwaahmad357
 
Role of herbs in hair care Amla and heena.pptx
Role of herbs in hair care  Amla and  heena.pptxRole of herbs in hair care  Amla and  heena.pptx
Role of herbs in hair care Amla and heena.pptxVaishnaviAware
 

Último (20)

001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...
001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...
001 Case Study - Submission Point_c1051231_attempt_2023-11-23-14-08-42_ABS CW...
 
MARSILEA notes in detail for II year Botany.ppt
MARSILEA  notes in detail for II year Botany.pptMARSILEA  notes in detail for II year Botany.ppt
MARSILEA notes in detail for II year Botany.ppt
 
Controlling Parameters of Carbonate platform Environment
Controlling Parameters of Carbonate platform EnvironmentControlling Parameters of Carbonate platform Environment
Controlling Parameters of Carbonate platform Environment
 
Principles & Formulation of Hair Care Products
Principles & Formulation of Hair Care  ProductsPrinciples & Formulation of Hair Care  Products
Principles & Formulation of Hair Care Products
 
Pests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdf
Pests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdfPests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdf
Pests of cumbu_Identification, Binomics, Integrated ManagementDr.UPR.pdf
 
Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...
Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...
Digitized Continuous Magnetic Recordings for the August/September 1859 Storms...
 
Main Exam Applied biochemistry final year
Main Exam Applied biochemistry final yearMain Exam Applied biochemistry final year
Main Exam Applied biochemistry final year
 
PSP3 employability assessment form .docx
PSP3 employability assessment form .docxPSP3 employability assessment form .docx
PSP3 employability assessment form .docx
 
Lehninger_Chapter 17_Fatty acid Oxid.ppt
Lehninger_Chapter 17_Fatty acid Oxid.pptLehninger_Chapter 17_Fatty acid Oxid.ppt
Lehninger_Chapter 17_Fatty acid Oxid.ppt
 
biosynthesis of the cell wall and antibiotics
biosynthesis of the cell wall and antibioticsbiosynthesis of the cell wall and antibiotics
biosynthesis of the cell wall and antibiotics
 
Basic Concepts in Pharmacology in molecular .pptx
Basic Concepts in Pharmacology in molecular  .pptxBasic Concepts in Pharmacology in molecular  .pptx
Basic Concepts in Pharmacology in molecular .pptx
 
soft skills question paper set for bba ca
soft skills question paper set for bba casoft skills question paper set for bba ca
soft skills question paper set for bba ca
 
MARKER ASSISTED SELECTION IN CROP IMPROVEMENT
MARKER ASSISTED SELECTION IN CROP IMPROVEMENTMARKER ASSISTED SELECTION IN CROP IMPROVEMENT
MARKER ASSISTED SELECTION IN CROP IMPROVEMENT
 
Pests of ragi_Identification, Binomics_Dr.UPR
Pests of ragi_Identification, Binomics_Dr.UPRPests of ragi_Identification, Binomics_Dr.UPR
Pests of ragi_Identification, Binomics_Dr.UPR
 
Exploration Method’s in Archaeological Studies & Research
Exploration Method’s in Archaeological Studies & ResearchExploration Method’s in Archaeological Studies & Research
Exploration Method’s in Archaeological Studies & Research
 
Data delivery from the US-EPA Center for Computational Toxicology and Exposur...
Data delivery from the US-EPA Center for Computational Toxicology and Exposur...Data delivery from the US-EPA Center for Computational Toxicology and Exposur...
Data delivery from the US-EPA Center for Computational Toxicology and Exposur...
 
TORSION IN GASTROPODS- Anatomical event (Zoology)
TORSION IN GASTROPODS- Anatomical event (Zoology)TORSION IN GASTROPODS- Anatomical event (Zoology)
TORSION IN GASTROPODS- Anatomical event (Zoology)
 
Cheminformatics tools supporting dissemination of data associated with US EPA...
Cheminformatics tools supporting dissemination of data associated with US EPA...Cheminformatics tools supporting dissemination of data associated with US EPA...
Cheminformatics tools supporting dissemination of data associated with US EPA...
 
CW marking grid Analytical BS - M Ahmad.docx
CW  marking grid Analytical BS - M Ahmad.docxCW  marking grid Analytical BS - M Ahmad.docx
CW marking grid Analytical BS - M Ahmad.docx
 
Role of herbs in hair care Amla and heena.pptx
Role of herbs in hair care  Amla and  heena.pptxRole of herbs in hair care  Amla and  heena.pptx
Role of herbs in hair care Amla and heena.pptx
 

Cerebellum by prc (1)

  • 1. CerebellumCerebellum ExternalExternal ConfigurationsConfigurations CerebellumCerebellum ExternalExternal ConfigurationsConfigurations - located in- located in posterior cranial fossaposterior cranial fossa - tentorium cerebelli (cerebrum), 4th ventricle (brain stem)- tentorium cerebelli (cerebrum), 4th ventricle (brain stem) - communicate with other structure via- communicate with other structure via superior, middle, and inferior cerebellar pedunclesuperior, middle, and inferior cerebellar peduncle -- longitudinal divisionlongitudinal division Vermis, Paravermal Region, Cerebellar HemisphereVermis, Paravermal Region, Cerebellar Hemisphere -- transverse divisiontransverse division Anterior LobeAnterior Lobe ------------------------ primary fissureprimary fissure Posterior LobePosterior Lobe ------------------------ posterolateral fissureposterolateral fissure Flocculonodular LobeFlocculonodular Lobe
  • 2. Subdivision ofSubdivision of Flocculonodular LobeFlocculonodular Lobe Nodulus FlocculusNodulus Flocculus Subdivision ofSubdivision of Anterior LobeAnterior Lobe Vermis HemisphereVermis Hemisphere LingulaLingula Central LobuleCentral Lobule Ala Central LobuleAla Central Lobule postcentral fissurepostcentral fissure CulmenCulmen Quadriangular LobuleQuadriangular Lobule CerebellumCerebellum ExternalExternal ConfigurationsConfigurations CerebellumCerebellum ExternalExternal ConfigurationsConfigurations
  • 3. Subdivision ofSubdivision of Posterior LobePosterior Lobe Vermis HemisphereVermis Hemisphere DecliveDeclive Simple LobuleSimple Lobule postcentral fissurepostcentral fissure FoliumFolium Superior Semilunar LobuleSuperior Semilunar Lobule horizontal fissurehorizontal fissure Inferior Semilunar LobuleInferior Semilunar Lobule TuberTuber Gracile LobuleGracile Lobule prepyramidal fissureprepyramidal fissure PyramisPyramis Biventer LobuleBiventer Lobule secondary fissuresecondary fissure UvulaUvula TonsilTonsil CerebellumCerebellum ExternalExternal ConfigurationsConfigurations CerebellumCerebellum ExternalExternal ConfigurationsConfigurations
  • 5. Cerebellar CortexCerebellar Cortex Molecular LayerMolecular Layer Purkinje Cell LayerPurkinje Cell Layer Granular LayerGranular Layer Corpus Medullare (Medullary Center)Corpus Medullare (Medullary Center) Deep Cerebellar NucleiDeep Cerebellar Nuclei Fastigial NucleiFastigial Nuclei Nucleus InterpositusNucleus Interpositus Emboliform NucleusEmboliform Nucleus Globose NucleusGlobose Nucleus Dentate NucleusDentate Nucleus CerebellumCerebellum InternalInternal ConfigurationsConfigurations CerebellumCerebellum InternalInternal ConfigurationsConfigurations
  • 6. 1. fastigial1. fastigial nucleusnucleus 2. globose2. globose nucleusnucleus 3. emboliform3. emboliform nucleusnucleus 4. dentate4. dentate nucleusnucleus Deep NucleiDeep Nuclei
  • 7. Cerebellar CortexCerebellar Cortex I. Molecular LayerI. Molecular Layer Stellate CellStellate Cell --- taurine (inhibitory)--- taurine (inhibitory) afferent:afferent: parallel fiberparallel fiber efferent: Purkinje cell dendriteefferent: Purkinje cell dendrite Basket CellBasket Cell ---- GABA (inhibitory)---- GABA (inhibitory) afferent:afferent: parallel fiberparallel fiber efferent: Purkinje cell somaefferent: Purkinje cell soma Parallel FiberParallel Fiber granule cell axongranule cell axon Purkinje Cell DendritePurkinje Cell Dendrite CerebellumCerebellum InternalInternal ConfigurationsConfigurations CerebellumCerebellum InternalInternal ConfigurationsConfigurations
  • 8. Cerebellar CortexCerebellar Cortex II. Purkinje Cell LayerII. Purkinje Cell Layer Purkinje CellPurkinje Cell -- 15,000,000 in number-- 15,000,000 in number -- GABA (inhibitory)-- GABA (inhibitory) afferent:afferent: parallel fiberparallel fiber climbing fiberclimbing fiber stellate cellstellate cell basket cellbasket cell efferent:efferent: deep cortical nucleideep cortical nuclei Bergman’s glial cellBergman’s glial cell CerebellumCerebellum InternalInternal ConfigurationsConfigurations CerebellumCerebellum InternalInternal ConfigurationsConfigurations
  • 9. Cerebellar CortexCerebellar Cortex III. Granular LayerIII. Granular Layer Granular CellGranular Cell -- 50,000,000,000 in number-- 50,000,000,000 in number -- glutamic acid (excitatory)-- glutamic acid (excitatory) afferent:afferent: mossy fibermossy fiber efferent:efferent: Purkinje cell dendritePurkinje cell dendrite basket cell, stellate cellbasket cell, stellate cell Golgi cellGolgi cell Golgi CellGolgi Cell -- GABA (inhibitory)-- GABA (inhibitory) afferent: parallel fiber, mossy fiber rosetteafferent: parallel fiber, mossy fiber rosette efferent: granule cell dendriteefferent: granule cell dendrite CerebellumCerebellum InternalInternal ConfigurationsConfigurations CerebellumCerebellum InternalInternal ConfigurationsConfigurations
  • 10. 1. Purkinje cell 2. granule cell 3. basket cell 4. Golgi cell 5. stellate cell 6. climbing fiber 7. mossy fiber 8. parallel fiber 9. inferior olivary nucleus 10. deep cerebellar nuclei
  • 12. Synaptic GlomerulusSynaptic Glomerulus Afferent terminals on granular layerAfferent terminals on granular layer  Mossy Fiber RosetteMossy Fiber Rosette -- afferent fibers except-- afferent fibers except inferior olivary inputinferior olivary input -- 2/3 of medullary center-- 2/3 of medullary center  Granular Cell DendriteGranular Cell Dendrite -- main afferent input-- main afferent input  Golgi Cell AxonGolgi Cell Axon -- synapse on granule cell dendrite-- synapse on granule cell dendrite -- GABA (inhibitory)-- GABA (inhibitory) -- Surrounded bySurrounded by AstrocyteAstrocyte Foot ProcessFoot Process CerebellumCerebellum InternalInternal ConfigurationsConfigurations CerebellumCerebellum InternalInternal ConfigurationsConfigurations
  • 14. Classification by Phylogenetic and Ontogenic DevelopmentClassification by Phylogenetic and Ontogenic Development ArchicerebellumArchicerebellum PaleocerebllumPaleocerebllum NeocerebellumNeocerebellum Classification by Afferent ConnectionClassification by Afferent Connection VestibulocerebellumVestibulocerebellum SpinocerebellumSpinocerebellum PontocerebellumPontocerebellum Classification by Efferent ConnectionClassification by Efferent Connection VermisVermis Paravermal RegionParavermal Region Cerebellar HemisphereCerebellar Hemisphere CerebellumCerebellum ClassificationsClassifications CerebellumCerebellum ClassificationsClassifications
  • 17. Afferent ConnectionsAfferent Connections (1):(1): 1. Inferior Cerebellar Peduncle1. Inferior Cerebellar Peduncle Restiform BodyRestiform Body Posterior Spinocerebellar TractPosterior Spinocerebellar Tract Olivocerebellar tractOlivocerebellar tract Cuneocerebellar TractCuneocerebellar Tract Reticulocerebellar TractReticulocerebellar Tract Juxtarestiform BodyJuxtarestiform Body Vestibulocerebellar TractVestibulocerebellar Tract Primary Vestyibular FiberPrimary Vestyibular Fiber CerebellumCerebellum ConnectionsConnections CerebellumCerebellum ConnectionsConnections
  • 18. Afferent ConnectionsAfferent Connections (2):(2): 2. Middle Cerebellar Peduncle2. Middle Cerebellar Peduncle Pontocerebellar fiberPontocerebellar fiber Corticopontocerebellar FiberCorticopontocerebellar Fiber Reticulocerebellar FiberReticulocerebellar Fiber 3. Superior Cerebellar Peduncle3. Superior Cerebellar Peduncle Anterior Spinocerebellar TractAnterior Spinocerebellar Tract Cerulocerebellar fiberCerulocerebellar fiber Raphecerebellar fiberRaphecerebellar fiber Rubrocerebellar fiberRubrocerebellar fiber Hypothalamocerebellar fiberHypothalamocerebellar fiber CerebellumCerebellum ConnectionsConnections CerebellumCerebellum ConnectionsConnections
  • 19. Efferent ConnectionsEfferent Connections :: 1. Superior Cerebellar Peduncle1. Superior Cerebellar Peduncle Cerebellothalamic fiberCerebellothalamic fiber - from 3 deep nuclei to VPLo, VLc, CL- from 3 deep nuclei to VPLo, VLc, CL Cerebellorubral fiberCerebellorubral fiber - from nucleus interpositus- from nucleus interpositus and dentate nucleusand dentate nucleus ascending portion ofascending portion of uncinate fasciculus of Russelluncinate fasciculus of Russell 2. Inferior Cerebellar Peduncle2. Inferior Cerebellar Peduncle Fastigiovestibular fiberFastigiovestibular fiber descending portion ofdescending portion of uncinate fasciculus of Russelluncinate fasciculus of Russell CerebellumCerebellum ConnectionsConnections CerebellumCerebellum ConnectionsConnections
  • 20. MLFMLF Main Connections of the VestibulocerebellumMain Connections of the VestibulocerebellumMain Connections of the VestibulocerebellumMain Connections of the Vestibulocerebellum lower motor neuronlower motor neuron LMNLMN vestibulospinal tractvestibulospinal tract FASTIGIALFASTIGIAL NUCLEUSNUCLEUS VestibularVestibular OrganOrgan FloculonodularFloculonodular LobeLobe VermisVermis ARCHICEREBELLUMARCHICEREBELLUM VESTIBULAR NUCLEUSVESTIBULAR NUCLEUS
  • 21. Main Connections of the PaleocerebellumMain Connections of the PaleocerebellumMain Connections of the PaleocerebellumMain Connections of the Paleocerebellum lower motor neuronlower motor neuron SPINAL CORDSPINAL CORD rubrospinalrubrospinal tracttract NUCLEUSNUCLEUS INTERPOSITUSINTERPOSITUS InferiorInferior OlivryOlivry NucleusNucleus ANTERIORANTERIOR LOBELOBE PARAVERMALPARAVERMAL ZONEZONE PALEOCEREBELLUMPALEOCEREBELLUM REDRED NUCLEUSNUCLEUS spinocerebellarspinocerebellar tracttract
  • 22. CEREBRALCEREBRAL CORTEXCORTEX CEREBRALCEREBRAL CORTEXCORTEX DENTATEDENTATE NUCLEUSNUCLEUS DENTATEDENTATE NUCLEUSNUCLEUS Main Connections of the NeocerebellumMain Connections of the NeocerebellumMain Connections of the NeocerebellumMain Connections of the Neocerebellum lower motor neuronlower motor neuron LMNLMN pyramidalpyramidal tracttract POSTERIORPOSTERIOR LOBELOBE CEREBELLARCEREBELLAR HEMISPHEREHEMISPHERE POSTERIORPOSTERIOR LOBELOBE CEREBELLARCEREBELLAR HEMISPHEREHEMISPHERE THALAMUSTHALAMUSTHALAMUSTHALAMUS NEOCEREBELLUMNEOCEREBELLUM PontinePontine NucleusNucleus PontinePontine NucleusNucleus
  • 23. upper motor neuronupper motor neuron UMNUMN upper motor neuronupper motor neuron UMNUMN BASALBASAL GANGLIAGANGLIA BASALBASAL GANGLIAGANGLIA Pyramidal Tract and Associated CircuitsPyramidal Tract and Associated CircuitsPyramidal Tract and Associated CircuitsPyramidal Tract and Associated Circuits lower motor neuronlower motor neuron UMNUMN lower motor neuronlower motor neuron UMNUMN pyramidal tractpyramidal tract CerebellumCerebellumCerebellumCerebellum
  • 24. Reticular Formation Reticular Formation CEREBELLUMCEREBELLUM Cerebellum and Automatic Motor ControlCerebellum and Automatic Motor ControlCerebellum and Automatic Motor ControlCerebellum and Automatic Motor Control Lower Motor Neuron (LMN)Lower Motor Neuron (LMN)Lower Motor Neuron (LMN)Lower Motor Neuron (LMN) Motor CortexMotor Cortex Red NucleusRed Nucleus Vestibular Nucleus Vestibular Nucleus ProprioceptorsProprioceptorsProprioceptorsProprioceptors
  • 25. Corticonuclear ConnectionsCorticonuclear Connections A zone ---------- fastigial nucleusA zone ---------- fastigial nucleus medial vestibular nucleusmedial vestibular nucleus B zone ---------- lateral vestibular nucleusB zone ---------- lateral vestibular nucleus CC11, C, C33 zone --- emboliform nucleuszone --- emboliform nucleus CC22 ---------------- globose nucleus---------------- globose nucleus DD11 ---------------- parvocellular portion of dentate nucleus---------------- parvocellular portion of dentate nucleus DD22 ---------------- magnocellular portion of dentate nucleus---------------- magnocellular portion of dentate nucleus CerebellumCerebellum ConnectionsConnections CerebellumCerebellum ConnectionsConnections
  • 26. 1. vermis1. vermis 2. paravermal2. paravermal regionregion 3. cerebella hemisphere3. cerebella hemisphere 4. nodulus4. nodulus 5. flocculus5. flocculus 6. fastigial6. fastigial nucleusnucleus 7. globose7. globose nucleusnucleus 8. emboliform8. emboliform nucleusnucleus 9. dentate9. dentate nucleusnucleus 10. medial vestibular10. medial vestibular nucleusnucleus 11. lateral vestibular11. lateral vestibular nucleusnucleus
  • 27. Olivocerebellar ConnectionsOlivocerebellar Connections Caudal portion ofCaudal portion of medial and dorsal accessory olivary nucleusmedial and dorsal accessory olivary nucleus ----------------- vermis of cerebellar cortex (A and B)----------------- vermis of cerebellar cortex (A and B) fastigial nucleusfastigial nucleus vestibular nucleusvestibular nucleus Rostral portion ofRostral portion of medial and dorsal accessory olivary nucleusmedial and dorsal accessory olivary nucleus ----------------- paravermal region (C----------------- paravermal region (C11, C, C22, C, C33)) nucleus interpositusnucleus interpositus Principal Inferior Olivary NucleusPrincipal Inferior Olivary Nucleus ----------------- cerebellar hemisphere (D----------------- cerebellar hemisphere (D11, D, D22)) dentate nucleusdentate nucleus CerebellumCerebellum ConnectionsConnections CerebellumCerebellum ConnectionsConnections
  • 28. medial and dorsal accessory olivary nucleusmedial and dorsal accessory olivary nucleus caudal portioncaudal portion rostral portionrostral portion PrincipalPrincipal Inferior OlivaryInferior Olivary NucleusNucleus
  • 29. CerebellumCerebellum FunctionFunction CerebellumCerebellum FunctionFunction  Maintenance of EquilibriumMaintenance of Equilibrium - balance, posture, eye movement- balance, posture, eye movement  Coordination of half-automatic movement ofCoordination of half-automatic movement of walking and posture maintenacewalking and posture maintenace - posture, gait- posture, gait  Adjustment of Muscle ToneAdjustment of Muscle Tone  Motor Leaning – Motor SkillsMotor Leaning – Motor Skills  Cognitive FunctionCognitive Function
  • 31. Motor SkillMotor Skill Pablo CasalsPablo Casals
  • 32. CerebellumCerebellum ClinicalClinical SyndromesSyndromes CerebellumCerebellum ClinicalClinical SyndromesSyndromes AtaxiaAtaxia: incoordination of movement: incoordination of movement - decomposition of movement- decomposition of movement - dysmetria, past-pointing- dysmetria, past-pointing - dysdiadochokinesia- dysdiadochokinesia - rebound phenomenon of Holmes- rebound phenomenon of Holmes - gait ataxia, truncal ataxia, titubation- gait ataxia, truncal ataxia, titubation IntentionIntention TremorTremor Hypotonia,Hypotonia, NystagmusNystagmus Archicerebellar LesionArchicerebellar Lesion: medulloblastoma: medulloblastoma Paleocerebellar LesionPaleocerebellar Lesion: gait disturbance: gait disturbance Neocerebellar LesionNeocerebellar Lesion: hypotonia, ataxia, tremor: hypotonia, ataxia, tremor
  • 33. PosturePosture Gait – AtaxiaGait – Ataxia TremorTremor
  • 34. CerebellarCerebellar AtaxiaAtaxia Ataxic gait andAtaxic gait and position:position: Left cerebellar tumorLeft cerebellar tumor a. Sways to the right ina. Sways to the right in standing positionstanding position b. Steady on theb. Steady on the right legright leg c. Unsteady on thec. Unsteady on the left legleft leg d. ataxic gaitd. ataxic gait a b c d
  • 35. Cerebellar tumors onCerebellar tumors on vermisvermis - Truncal Ataxia- Truncal Ataxia - Frequent Falling- Frequent Falling The child in this picture:The child in this picture: - would not try to stand- would not try to stand unsupportedunsupported - would not let go of the bed rail- would not let go of the bed rail if she was stood on the floor.if she was stood on the floor. CerebellarCerebellar MedulloblastomaMedulloblastoma