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General
Pathophysiology of a
disease in Ayurveda
Abnormal states of Doshas
Dr.Kishor Patwardhan
Increased Vata
 Emaciation
 Black discoloration
 Desire for hot substances
 Tremors
 Abdominal distention
 Constipations
 Loss of strength, sleep and sensorial functions
 Irrelevant speech
 Giddiness
 Helplessness
Decreased Vata
 Debility
 Decreased speech and movements
 Loss of sensations
 Symptoms of increased Kapha
Increased Pitta
 Yellow coloration of faeces, urine, eyes and skin
 Excessive hunger
 Excessive thirst
 Burning sensation
 Loss of sleep
Decreased Pitta
 Weak digestion and metabolism
 Coldness
 Loss of natural complexion
Increased Kapha
 Weak digestion and metabolism
 Excessive salivation
 Lethargy
 Heaviness
 Whitish discoloration
 Feeling of coldness
 Looseness of the body parts
 Dyspnoea
 Cough
 Excessive sleep
Decreased Kapha
 Dizziness
 Emptiness in the sites of Kapha
 Palpitation
 Loose joints
Samprapti -
pathogenesis.
Sushruta
describes six
successive
stages of
manifestation
of a disease
During each
stage, a
physician has
an opportunity
to treat the
subject.
These
successive
stages are
known as
Kriyakala.
Six stages of
a disease
Sanchaya (Accumulation)
Prakopa (Aggravation)
Prasara (Spread)
Sthana samshraya (Localization)
Vyakti (Manifestation)
Bheda (Differentiation)
 In this stage morbid Doshas start
accumulating in their own primary
sites.
 Dislike for substances which are the
causes of the accumulation
 Liking for the substances of opposite
nature.
Sanchaya
(Accumulation)
In this stage mild symptoms are seen.
Accumulation of Vata:
Sense of abdominal distention
Accumulation of Pitta:
Yellowish nails, eyes and urine
Accumulation of Kapha:
Feeling cold, lethargy
Symptoms
If one treats the disease at the
stage of Sancaya, the disease does
not spread further.
If this stage is not recognized and
the person continues to indulge in
unhealthy foods etc., the Doshas
aggravate further.
 In this stage Doshas go on
accumulating further even in their
secondary sites.
Prakopa
(Aggravation)
Symptoms

 Vata Abdominal pain
 Hyper peristalsis
 Pitta Water brash
 Polydypsia
 Burning sensation
 Kapha Nausea
 Heaviness in chest
 The morbid Doshas are hyper-activated
and invade the sites of other Doshas in
addition to their own; Vata to the sites
of Pitta and Kapha etc.
 They also move out of the Koshtha
(Center, Core) to Shakha (periphery)
being transported by the circulating
Rasa Dhatu.
Prasara
(Spread)
The person develops mild to
moderate symptoms in this
stage.
If effective treatment
becomes available , the
Doshas come back to
normal; otherwise
abnormality continues
further to the onset of the
fourth stage.
Symptoms
 Vata Tympanitis
 Pitta Fever
 Burning sensation
 Kapha Anorexia
 Indigestion
 Fatigue
 Nausea
 Unhealthy food and activities lead
to an aggravation in the Doshas.
 Mild abnormalities in –
 Jatharagni
 Dhatus
 Srotas
 Ojas
During the first
three stages:
Sthana
Samshraya
(Localization)
The aggravated Doshas which were
circulating all over the body along
with Rasa Dhatu, now tend to get
lodged at certain places in the Dhatus
Localization occurs at the weakest site
of a Srotas
Bring about abnormalities in the
Srotas
 The Dhatus have their defense, Ojas,
which is responsible for their strength,
to carryout their functions, to prevents
the disease in case of its happening.
 The decrease of Ojas makes the Dhatus
poor in strength and susceptible to the
bad effect of the morbid Doshas.
 Further increase of the Doshas
 Union of abnormal Doshas and Dushyas
 Localization of Doshas at certain places
 Decrease of Ojas
 Deformities of Srotas
 Accumulation of Ama
All these act as essential
prerequisite for the onset of
the disease.
Result of these acts appears as
Puvarupa (prodromal
symptoms).
Vyakti
(Manifestation)
In this stage, the disease expresses
itself with all its characteristic
symptoms and signs.
These symptoms and signs are very
clearly recognizable without doubt.
The diseases are given specific names
based on the chief symptom/sign, the
organ affected and many other
factors.
 The abnormalities can be brought to normalcy
when effective treatment and all other
favorable factors are present.
Bheda
(Differentiation)
This is the last stage
All the abnormalities become
still more profound and
irreversible.
In spite of the best treatment,
they continue to persist.

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General patho physiology in Ayurveda (Kriyakala)

  • 2. Abnormal states of Doshas Dr.Kishor Patwardhan
  • 3. Increased Vata  Emaciation  Black discoloration  Desire for hot substances  Tremors  Abdominal distention  Constipations  Loss of strength, sleep and sensorial functions  Irrelevant speech  Giddiness  Helplessness
  • 4. Decreased Vata  Debility  Decreased speech and movements  Loss of sensations  Symptoms of increased Kapha
  • 5. Increased Pitta  Yellow coloration of faeces, urine, eyes and skin  Excessive hunger  Excessive thirst  Burning sensation  Loss of sleep
  • 6. Decreased Pitta  Weak digestion and metabolism  Coldness  Loss of natural complexion
  • 7. Increased Kapha  Weak digestion and metabolism  Excessive salivation  Lethargy  Heaviness  Whitish discoloration  Feeling of coldness  Looseness of the body parts  Dyspnoea  Cough  Excessive sleep
  • 8. Decreased Kapha  Dizziness  Emptiness in the sites of Kapha  Palpitation  Loose joints
  • 9. Samprapti - pathogenesis. Sushruta describes six successive stages of manifestation of a disease During each stage, a physician has an opportunity to treat the subject. These successive stages are known as Kriyakala.
  • 10. Six stages of a disease Sanchaya (Accumulation) Prakopa (Aggravation) Prasara (Spread) Sthana samshraya (Localization) Vyakti (Manifestation) Bheda (Differentiation)
  • 11.  In this stage morbid Doshas start accumulating in their own primary sites.  Dislike for substances which are the causes of the accumulation  Liking for the substances of opposite nature. Sanchaya (Accumulation)
  • 12. In this stage mild symptoms are seen. Accumulation of Vata: Sense of abdominal distention Accumulation of Pitta: Yellowish nails, eyes and urine Accumulation of Kapha: Feeling cold, lethargy Symptoms
  • 13. If one treats the disease at the stage of Sancaya, the disease does not spread further. If this stage is not recognized and the person continues to indulge in unhealthy foods etc., the Doshas aggravate further.
  • 14.  In this stage Doshas go on accumulating further even in their secondary sites. Prakopa (Aggravation)
  • 15. Symptoms   Vata Abdominal pain  Hyper peristalsis  Pitta Water brash  Polydypsia  Burning sensation  Kapha Nausea  Heaviness in chest
  • 16.  The morbid Doshas are hyper-activated and invade the sites of other Doshas in addition to their own; Vata to the sites of Pitta and Kapha etc.  They also move out of the Koshtha (Center, Core) to Shakha (periphery) being transported by the circulating Rasa Dhatu. Prasara (Spread)
  • 17. The person develops mild to moderate symptoms in this stage. If effective treatment becomes available , the Doshas come back to normal; otherwise abnormality continues further to the onset of the fourth stage.
  • 18. Symptoms  Vata Tympanitis  Pitta Fever  Burning sensation  Kapha Anorexia  Indigestion  Fatigue  Nausea
  • 19.  Unhealthy food and activities lead to an aggravation in the Doshas.  Mild abnormalities in –  Jatharagni  Dhatus  Srotas  Ojas During the first three stages:
  • 20. Sthana Samshraya (Localization) The aggravated Doshas which were circulating all over the body along with Rasa Dhatu, now tend to get lodged at certain places in the Dhatus Localization occurs at the weakest site of a Srotas Bring about abnormalities in the Srotas
  • 21.  The Dhatus have their defense, Ojas, which is responsible for their strength, to carryout their functions, to prevents the disease in case of its happening.  The decrease of Ojas makes the Dhatus poor in strength and susceptible to the bad effect of the morbid Doshas.
  • 22.  Further increase of the Doshas  Union of abnormal Doshas and Dushyas  Localization of Doshas at certain places  Decrease of Ojas  Deformities of Srotas  Accumulation of Ama
  • 23. All these act as essential prerequisite for the onset of the disease. Result of these acts appears as Puvarupa (prodromal symptoms).
  • 24. Vyakti (Manifestation) In this stage, the disease expresses itself with all its characteristic symptoms and signs. These symptoms and signs are very clearly recognizable without doubt. The diseases are given specific names based on the chief symptom/sign, the organ affected and many other factors.
  • 25.  The abnormalities can be brought to normalcy when effective treatment and all other favorable factors are present.
  • 26. Bheda (Differentiation) This is the last stage All the abnormalities become still more profound and irreversible. In spite of the best treatment, they continue to persist.

Notas del editor

  1. dhātus Koṣṭhagni