12. UpToDateを調べる
流行期に咳と熱がある患者
79%がインフルエンザ
In a retrospective pooled analysis of signs and symptoms
in 3744 adolescents and adults with an influenza-like
illness who participated in phase II and III trials of
neuraminidase inhibitors during outbreaks [1], the best
multivariate predictor was the combination of fever and
cough within 48 hours of the development of symptoms,
which had a positive predictive value of 79 percent for
documented influenza.
Arch Intern Med. 2000;160(21):3243.
15. UpToDateを調べる
感度62% 特異度98%
In a meta-analysis of 159 studies that evaluated rapid
influenza antigen tests, the pooled sensitivity was 62
percent (95% CI 58-67 percent) and the pooled specificity
was 98 percent (95% CI 98-99 percent) [17].
Ann Intern Med. 2012;156(7):500.
感度54%
In a subsequent meta-analysis, the pooled sensitivity was
54 percent for influenza A viruses and 53 percent for
influenza B viruses [12].
Ann Intern Med. 2017;167(6):394.