NMR

1. PRESENTATION ON:
NUCLEAR MAGNETIC RESONANCE
SPECTROSCOPY (NMR)
INTEGRAL UNIVERSITY,LUCKNOW
Session: 2016-2017
Presented by: Under the guidence of:
Mohd Muztaba
M.Pharm Mr. Paramdeep Bagga
Pharmacology

2. INTRODUCTION
 Nuclear magnetic resonance spectroscopy(NMR) is a powerful
analytical technique used to characterize organic molecules by
identifying carbon-hydrogen frameworks within molecules.
 It is a research technique that exploits the magnetic properties
of certain atomic nuclei.
 It determines the physical and chemical properties of atoms or
the molecules in which they are contained.

3. Types of NMR
• Two common types of NMR spectroscopy are used to
characterize organic structure:
– 1H NMR:- Used to determine the type and number of H
atoms in a molecule
– 13C NMR:- Used to determine the type of carbon atoms in
the molecule

4. • The theory behind NMR comes from the spin of
a nucleus and it generates a magnetic field.
• Without an external applied magnetic field, the
nuclear spins are random in directions.
• But when an external magnetic field (BO) is
present, the nuclei align themselves either with
or against the field of the external magnet.
Principles of NMR

5.  If an external magnetic field is applied, an energy
transfer (∆E) is possible between ground state to excited
state
 When the spin returns to its ground state level, the
absorbed radiofrequency energy is emitted at the same
frequency level.
 The emitted radiofrequency signal gives the NMR
spectrum of the concerned nucleus.

6. APPLICATION
 It is use to identification of structrul isomertism
eg. n-propanol ,isopropanol
 Identification of H bonding
 Use for determination of aromaticities of compound
 NMR technique use to distinguish betweeen cis and trans
isomer
 Detection of Electronegative atom
 Detection of some double bond character due to resonance

7. We hope you liked our presentation.
• Thank you! 