10. Newcastle disease
• Notifiable disease !
• Avian paramyxovirus (serotype 1, 8
genotypes)
• different pathogenity (v, m, l, a)
• chicken, pheasant, turkey, pigeon, wild birds
(water fowl)
• Sensitivity: 56 °C - 3 min
pH 3 - 3 min disinfectant
11. Examples Of ICPI Of Several NDV Isolates
Virus Product ICPI
Ulster 2C Poulvac NDW 0.04 to 0.23
PHY.LMV.42 Cevac® VITAPEST L 0.16
Hitchner B1 Many 0.18
Clone 30 Nobilis® ND Clone 30 0.25
VG/GA AVINEW®
0.30
La Sota Many 0.4
Komarov 1.41
12. • Clinical signs:
respiratory disease
enteritidis
nervous signs
marked drop in egg production
• Pathology:
– haemorrhages on seromembranes,
on mucosal membranes
(proventriculi, small intestine,
ceca, -lymphoid tonsils -,
trachea, pharynx)
– enteritidis
– diphtheriod inflammation on lymphoid tonsils
on pharynx
19. Fowl pox
• Poxviridae, Avipox
• Sensitivity: 50°C heating 30 min
60°C 8 min
in dry scabs for months/years
pH 5-9 resistant
20. • cutaneous form
nodular (proliferative) lesions on the comb,
wattle, eyelids, other non feathered areas
• diphtheroid form
nodules on mucosal membranes of pharynx,
trachea, oesophagus
• special histopathological changes
(cytoplasmic inclusion body)
25. Infectious Laryngotracheitis
• Herpesvirus
• Sensitivity: mild (halogen-detergents + iodophors, heating,
but (-18° C-25° C !)
• Acute respiratory disease
• Conjunctivitis
Laryngitis
Tracheitis
(Histopathology: intranuclear inclusion body in
epithelial cells by 3 day PI)
27. Infectious bronchitis
• Coronavirus
• Sensitivity: 56°C 15 min
at room temperature 2-3 days
common detergents destroy
• Pathology:
acute catarrhal tracheitis, bronchitis
sinusitis, air sacculitis
local pneumonia
• nephritis, salpingitis (eggs !)
32. Infectious bursal Disease
(Gumboro Disease)
• Birnavirus
• Bursa Fabricius (B lymphoid cells)
immunosuppression !
• Sensitivity: very stable virus!
60-70°C -30 min
0.5 % chloramines 10 min
invert soap + 0,05 sodium hydroxide
33. • Pathology:
haemorrhages
in muscles (legs, breast)
on mucosal membrane of proventriculi
on lymphoid tonsils of intestine
oedema and haemorrhageous inflammation of
bursa Fabricii
• Diff. diagnosis: Newcastle disease
mycotoxicosis
• Prevention: vaccination, hygiene
35. Marek’s Disease
• Herpesvirus (cell associated virus)
• Sensitivity:
• Pathogenity:
„classical” form (lesions in peripheral nerves)
tumoral form
(lymphoid tumors in different organs or
in skin)
transient paralysis
• Differential diagnosis:
Newcastle disease
leucosis
tumors
51. In these cases poultry meat is partial
condemned for human consumption
(the effected areas are condemned:
- parenchymal orgams
- intestines
- skin + muscles /breast, legs/ )