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EXAMINATION
OF
UNCONSIOUS
PATIENT
- DR. KRUPAL MODI
- ASSISTANT PROFESSOR
- SSPTC
- KADODARA.
 In hospital neurology, the clinical analysis of
unresponsive and comatose patients
becomes a practical necessity. There is
always an urgency about such medical
problems.
 CAUSES FOR UNCONSIOUSNESS :
 “mass lesions,”—such as tumors, abscesses,
hemorrhages, and infarcts.
 exogenous (drug overdose) and endogenous
(metabolic) intoxications and hypoxia.
 Subarachnoid hemorrhage, meningitis, and
encephalitis etc….
 Normal Consciousness :
 This is the condition of the normal person
when awake.
 In this state the individual is fully
responsive to stimuli and indicates by his
behavior and speech the same awareness of
self and environment as that of the examiner.
 Unconsciousness has the opposite
meaning—
 A state of unawareness of self and
environment or a suspension of those mental
activities by which people are made aware of
themselves and their environment, coupled
with a diminished responsiveness to
environmental stimuli.
 level of consciousness—
 meaning the state of arousal or the degree of
variation from normal alertness as judged by
the appearance of facial muscles, fixity of
gaze, and body posture.
CAUSES for
unconsciousness
 Intracranial :
Trauma
Tumor with oedema
Subarachnoid hemorrhage
epilepsy, hydrocephalus, encephalitis
 Extracranial :
Diabetes
hypothyroidism
Lactic acidosis etc.
 Arterial occlusions
 Respiratory insufficiency
 Drugs
 toxins
 When the comatose patient is first seen, one must
quickly make sure that the patient's airway is clear and
the patient is not in shock.
 If trauma has occurred, one must check for bleeding
from a wound or ruptured organ (e.g., spleen or liver).
 If hypotension is present, certain therapeutic
measures—placement of a central venous line and
administration of fluids and pressor agents, oxygen,
blood, or glucose solutions .
 If respirations are shallow or labored or if
there is emesis with a threat of aspiration,
tracheal intubation and mechanical ventilation
are required.
The key components of the neurological
examination of the comatose patient
are:
 Examine level of consciousness (Glasgow
Coma Score
 The pattern of breathing
 size and reactivity of the pupils
 eye movements and oculovestibular
responses
 motor responses (tone, reflexes and
posturing)
 meningism and signs of the underlying cause
GENERAL EXAMINATION
 Consider the neurological findings in light of the
vital signs, evidence of trauma, acute or
chronic illness, and/or drug ingestion
 Cranial scars, drains, ICP monitors and VP
shunts.
 Neck stiffness
 Infusions (e.g. sedatives, nimodipine,
vasopressors)
 ventilator (type , mode , setting, evidence of
spontaneous breaths)
GCS : The Glasgow Coma Scale, constructed originally as a
quick and simple means of quantitating the responsiveness of
patients with severe cerebral trauma, can be used in the grading of
other acute coma-producing diseases.
PATTERN OF BREATHING
 Cheyne-Stokes respiration is not specific
but is seen in lesions above the brainstem.
 Central hyperventilation, or prolonged
inspiratory pauses or irregular ataxic
breathing indicates various brainstem lesions
as does apnea.
 Also look for deep rapid Kussmaul
breathing, secondary to a metabolic acidosis,
as in diabetes ketoacidosis.
 Look for spontaneous breaths in the
ventilated patient .
PUPILLARY RESPONSES
 Assess the pupils for size, asymmetry and
reactivity to light.
 Different sized pupils correspond to different types
of lesions.
 pinpoint pupils occur in pontine lesions and
certain overdoses (e.g. opioid, clonidine).
 fixed mid-sized pupils occur in midbrain lesions
 One dilated pupil suggests CN3 compression –
e.g. ICH, aneurysm or raised ICP.
OCULOVESTIBULAR
REFLEXES
Oculocephalic reflex (‘doll’s eye’
reflex)
 The patient’s eyes are held open
 The head is briskly turned from side to side
with the head held briefly at the end of each
turn.
 A positive response occurs when the eyes rotate
to the opposite side to the direction of head
rotation, thus indicating that the brainstem
(CN3,6,8) is intact.
 a similar result is seen when the head is flexed
and extended — a positive result is downward
deviation of the eyes during extension, and
upward deviation during flexion These vertical
responses indicates that the brainstem (CN3,4,8)
is intact.
• The eyes
should gradually
return to the mid-
position in a smooth,
conjugate
movement if the
brainstem is intact.
• Patients with
metabolic coma
(e.g. hepatic failure)
may have
exaggerated, brisk
oculocephalic
reflexes.
Oculovestibular reflex (caloric
stimulation)
 the head is elevated to 30 degrees above
horizontal so that the lateral semicircular canal is
vertical, and so that stimulation with generate a
maximal response.
 Introduce iced water into the external ear
canal through a small cather until one of the
following occurs:
— nystagmus (in the intact brainstem the slow
phase is towards the irrigated ear)
— ocular deviation
— 200mL of iced water has been instilled
 allow 5 minutes between testing ears to allow re-
equilibration of the oculovestibular system.
MOTOR RESPONSES
 POSTURING can occur spontaneously or in
response to a stimulus.
 Abnormal flexion is decorticate posturing —
adduction of arm, internal rotation of shoulder,
pronation of forearm, flexion of wrist (lower limbs
are extended); indicates a lesion above the
brainstem.
 Extension is decerebrate posturing — abduction
of arm, external rotation of shoulder, supination of
forearm, extension of wrist (lower limbs are
extended); indicates a lesion extending to the
midbrain or below.
 Assess for:
 Tone
 Clonus
 Deep tendon reflexes
 Planter reflexes
 involuntary movements (such as subtle signs
of seizures and myoclonus)
Investigations:
 If trauma, signs of raised ICP or focal
neurological signs and meningism is
suspected,
 Then CT Scan , Lumber puncture- CSF
examination is done.
 Skull X-Ray : to find out unsuspected
fractures, calcification or an osteolytic lesion.
 Chest X –Ray : may reveal bronchial
carcinoma.
 Electroencephalography:
may provide evidence of : Epilepy,
Encephalitis, Metabolic encephalopathy.
 MRI : it has a very less role in the
investigation of coma.
Examination of unconsious patient

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Examination of unconsious patient

  • 1. EXAMINATION OF UNCONSIOUS PATIENT - DR. KRUPAL MODI - ASSISTANT PROFESSOR - SSPTC - KADODARA.
  • 2.  In hospital neurology, the clinical analysis of unresponsive and comatose patients becomes a practical necessity. There is always an urgency about such medical problems.  CAUSES FOR UNCONSIOUSNESS :  “mass lesions,”—such as tumors, abscesses, hemorrhages, and infarcts.  exogenous (drug overdose) and endogenous (metabolic) intoxications and hypoxia.  Subarachnoid hemorrhage, meningitis, and encephalitis etc….
  • 3.  Normal Consciousness :  This is the condition of the normal person when awake.  In this state the individual is fully responsive to stimuli and indicates by his behavior and speech the same awareness of self and environment as that of the examiner.
  • 4.  Unconsciousness has the opposite meaning—  A state of unawareness of self and environment or a suspension of those mental activities by which people are made aware of themselves and their environment, coupled with a diminished responsiveness to environmental stimuli.
  • 5.  level of consciousness—  meaning the state of arousal or the degree of variation from normal alertness as judged by the appearance of facial muscles, fixity of gaze, and body posture.
  • 6. CAUSES for unconsciousness  Intracranial : Trauma Tumor with oedema Subarachnoid hemorrhage epilepsy, hydrocephalus, encephalitis  Extracranial : Diabetes hypothyroidism Lactic acidosis etc.
  • 7.  Arterial occlusions  Respiratory insufficiency  Drugs  toxins
  • 8.  When the comatose patient is first seen, one must quickly make sure that the patient's airway is clear and the patient is not in shock.  If trauma has occurred, one must check for bleeding from a wound or ruptured organ (e.g., spleen or liver).  If hypotension is present, certain therapeutic measures—placement of a central venous line and administration of fluids and pressor agents, oxygen, blood, or glucose solutions .
  • 9.  If respirations are shallow or labored or if there is emesis with a threat of aspiration, tracheal intubation and mechanical ventilation are required.
  • 10. The key components of the neurological examination of the comatose patient are:  Examine level of consciousness (Glasgow Coma Score  The pattern of breathing  size and reactivity of the pupils  eye movements and oculovestibular responses  motor responses (tone, reflexes and posturing)  meningism and signs of the underlying cause
  • 11. GENERAL EXAMINATION  Consider the neurological findings in light of the vital signs, evidence of trauma, acute or chronic illness, and/or drug ingestion  Cranial scars, drains, ICP monitors and VP shunts.  Neck stiffness  Infusions (e.g. sedatives, nimodipine, vasopressors)  ventilator (type , mode , setting, evidence of spontaneous breaths)
  • 12. GCS : The Glasgow Coma Scale, constructed originally as a quick and simple means of quantitating the responsiveness of patients with severe cerebral trauma, can be used in the grading of other acute coma-producing diseases.
  • 13. PATTERN OF BREATHING  Cheyne-Stokes respiration is not specific but is seen in lesions above the brainstem.  Central hyperventilation, or prolonged inspiratory pauses or irregular ataxic breathing indicates various brainstem lesions as does apnea.  Also look for deep rapid Kussmaul breathing, secondary to a metabolic acidosis, as in diabetes ketoacidosis.  Look for spontaneous breaths in the ventilated patient .
  • 14.
  • 15. PUPILLARY RESPONSES  Assess the pupils for size, asymmetry and reactivity to light.  Different sized pupils correspond to different types of lesions.  pinpoint pupils occur in pontine lesions and certain overdoses (e.g. opioid, clonidine).  fixed mid-sized pupils occur in midbrain lesions  One dilated pupil suggests CN3 compression – e.g. ICH, aneurysm or raised ICP.
  • 16.
  • 17. OCULOVESTIBULAR REFLEXES Oculocephalic reflex (‘doll’s eye’ reflex)  The patient’s eyes are held open  The head is briskly turned from side to side with the head held briefly at the end of each turn.  A positive response occurs when the eyes rotate to the opposite side to the direction of head rotation, thus indicating that the brainstem (CN3,6,8) is intact.  a similar result is seen when the head is flexed and extended — a positive result is downward deviation of the eyes during extension, and upward deviation during flexion These vertical responses indicates that the brainstem (CN3,4,8) is intact.
  • 18. • The eyes should gradually return to the mid- position in a smooth, conjugate movement if the brainstem is intact. • Patients with metabolic coma (e.g. hepatic failure) may have exaggerated, brisk oculocephalic reflexes.
  • 19. Oculovestibular reflex (caloric stimulation)  the head is elevated to 30 degrees above horizontal so that the lateral semicircular canal is vertical, and so that stimulation with generate a maximal response.  Introduce iced water into the external ear canal through a small cather until one of the following occurs: — nystagmus (in the intact brainstem the slow phase is towards the irrigated ear) — ocular deviation — 200mL of iced water has been instilled  allow 5 minutes between testing ears to allow re- equilibration of the oculovestibular system.
  • 20.
  • 21. MOTOR RESPONSES  POSTURING can occur spontaneously or in response to a stimulus.  Abnormal flexion is decorticate posturing — adduction of arm, internal rotation of shoulder, pronation of forearm, flexion of wrist (lower limbs are extended); indicates a lesion above the brainstem.  Extension is decerebrate posturing — abduction of arm, external rotation of shoulder, supination of forearm, extension of wrist (lower limbs are extended); indicates a lesion extending to the midbrain or below.
  • 22.
  • 23.  Assess for:  Tone  Clonus  Deep tendon reflexes  Planter reflexes  involuntary movements (such as subtle signs of seizures and myoclonus)
  • 24. Investigations:  If trauma, signs of raised ICP or focal neurological signs and meningism is suspected,  Then CT Scan , Lumber puncture- CSF examination is done.  Skull X-Ray : to find out unsuspected fractures, calcification or an osteolytic lesion.
  • 25.  Chest X –Ray : may reveal bronchial carcinoma.  Electroencephalography: may provide evidence of : Epilepy, Encephalitis, Metabolic encephalopathy.  MRI : it has a very less role in the investigation of coma.