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The Chemistry of Vision April 17, 2008 Andrew Isleib Eric Sterne Jonathan Arnold Min Eun Lee Samara Shiromani
Agenda ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object]
Introduction: Sources of Vitamin A (Retinol) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction: The Eye ,[object Object],Retina Rod Cells Cone Cell
[object Object],[object Object],[object Object],Introduction: Rhodopsin
Introduction: Phototransduction ,[object Object],11-Cis Retinal
Introduction: Phototransduction ,[object Object],“ All-Trans” Retinal
Chemistry: Retinal Binding ,[object Object],[object Object]
Chemistry: Rhodopsin Absorption   ,[object Object],[object Object],[object Object],[object Object],[object Object],MO Energy HOMO LUMO HOMO LUMO Retinal Rhodopsin  max = 370nm   max = 498nm  MO Energy
Color Vision: Cone Cells
Color Vision ,[object Object]
Ishihara Test ,[object Object]
Color Blindness ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Losing the Light ,[object Object]
Normal Retina
Retina with AMD
Progression of AMD
Chemistry: A2E-epoxides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object]
ß-Carotene
Vitamin A - All Trans Retinol ,[object Object],[object Object]
Retinal to Vitamin A
Ishihara Test

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Chemistry Of Vision Final