This document discusses patellofemoral pain syndrome (PFPS). PFPS is characterized by anterior knee pain that is most common in young, active populations. It is typically caused by an imbalance of forces across the patellofemoral joint from issues like increased Q-angle, foot overpronation, and weakness of the vastus medialis obliquus muscle. Symptoms include pain around or behind the kneecap that is aggravated by activities involving knee bending like squatting or going up and down stairs. Treatment focuses on reducing pain/inflammation, addressing contributing biomechanical factors, and strengthening exercises for the quadriceps muscles.
4. Patellofemoral Pain Syndrome
• Anterior knee pain
• Most common cause in young population
• Young female atheletes
• Gradual onset
• Aggravated at
• Squat
• Stair up/down
• Sit to stand
• Knee flexion
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6. PFPS
• Pain sources
• Peripatellar synovitis without obvious cartilage damage
• Soft tissues such as lateral retinaculum
• Infrapatellar fat pad
• Self limited conditions
• No disability
• Benign neglect
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7. Pathophysiology
• Increased tension of patella to lateral side due to
• Overpronation of foot
• Increased Q-angle
• VMO weakness
• Muscle power imbalance
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13. 2016-05-11
1. Sheehan FT, Borotikar BS, Behnam AJ, Alter KE. Alterations in in vivo knee joint kinematics following
a femoral nerve branch block of the vastus medialis: Implications for patellofemoral pain syndrome. JCLB. Elsevier
B.V; 2012 Jul 1;27(6):525–31.
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14. 2016-05-11
1. Sheehan FT, Borotikar BS, Behnam AJ, Alter KE. Alterations in in vivo knee joint kinematics following
a femoral nerve branch block of the vastus medialis: Implications for patellofemoral pain syndrome. JCLB. Elsevier
B.V; 2012 Jul 1;27(6):525–31.
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15. Physical Exam
• Palpation
• Localized edema/tenderness
• Patellar glide test
• Lateral glide, more than 50%
• Patellar tilt test
• Lateral tilt, less than 0 degree
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33. Botulinum Toxin
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1. PG2166. Botulinum Toxin Type A for Nonsurgical Lateral Release in Patellofemoral Pain Syndrome:
A Case Study. 2011 May 19;:1–3.
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1. Väätäinen U, Lohmander LS, Thonar E, Hongisto T, Ågren U, Rönkkö S, et al. Markers of cartilage
and synovial metabolism in joint fluid and serum of patients with chondromalacia of the patella. Osteoarthritis and
Cartilage. 1998 Mar;6(2):115–24.
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41. 2016-05-11
1. Naslund JE, Odenbring S, Näslund U-B, Lundeberg T. Diffusely increased bone scintigraphic uptake
in patellofemoral pain syndrome. British Journal of Sports Medicine. BMJ Publishing Group Ltd and British
Association of Sport and Exercise Medicine; 2005 Mar;39(3):162–5.
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42. Take Home!
• Patellofemoral Pain Syndrome
• Common cause of anterior knee pain
• Biomechanical problems of patella
• Exercise – VMO retraining
• Only Naproxen (VIMOVO) has evidence
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