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抗癌药( Anti-Cancer Drugs )   北京协和医学院基础医学院 药理学系 叶菜英
Overview   ,[object Object],[object Object],[object Object]
Overview ,[object Object],[object Object]
Advances in Cancer Chemotherapy   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Advances in Cancer Chemotherapy ,[object Object],[object Object],[object Object],[object Object]
Cancer Chemotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cancer Chemotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Classification of Anticancer Drugs ,[object Object],[object Object],[object Object]
The Classification of Anticancer Drugs ,[object Object],[object Object]
The Classification of Anticancer Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Classification of Anticancer Drugs ,[object Object],[object Object],[object Object]
The Basic Concept of  Cell Generation Cycle ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Growth Fraction (GF) GF = Proliferating cell group Total tumor cell group CCNSA : drugs that are active throughout the cell cycle. CCSA:  drugs that act during a specific phase of the cell cycle.
Cell cycle specific agents and Cell cycle  Non-specific agents ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cell cycle specific agents and Cell cycle  Non-specific agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mechanism of Anticancer Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object]
Block Nucleic Acid (DNA, RNA) Biosynthesis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Interfere Protein Synthesis  ,[object Object],[object Object],[object Object],[object Object]
Interfere Transcription and Block RNA Synthesis ,[object Object]
Influence the Structure and Function of DNA ,[object Object],[object Object],[object Object],[object Object],[object Object]
Influence  Hormone Homeostasis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Long Road of a New Medicine
The Main Step of Anticancer Drug Research   ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Main Step of Anticancer Drug Research ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Main Step of Anticancer Drug Research ,[object Object],[object Object],[object Object],[object Object]
The Main Step of Anticancer Drug Research ,[object Object],[object Object]
The Main Step of Anticancer Drug Research ,[object Object],[object Object]
The Main Step of Anticancer Drug Research ,[object Object],[object Object]
Anticancer Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Alkylating Agents ,[object Object]
Alkylating Agents ,[object Object],[object Object]
Classification of  Alkylating Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Resistance of  Alkylating Agents ,[object Object],[object Object],[object Object],[object Object]
Adverse Effects of  Alkylating Agents ,[object Object],[object Object],[object Object]
Alkylating Agents——Mustine ,[object Object],[object Object]
Alkylating Agents——  Cyclophosphamide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Alkylating Agents——Nitrosoureas ,[object Object],[object Object],[object Object],[object Object],[object Object]
Alkylating Agents——   Phenylalanine Nitrogen Mustard ,[object Object]
Alkylating Agents——   Alkysulfonates ,[object Object],[object Object],[object Object],[object Object],[object Object]
Alkylating Agents—— Thiotepa ,[object Object]
Antimetabolites ,[object Object],[object Object],[object Object]
Classification of Antimetabolites ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antimetabolites—— Folic Acid Antagonist ,[object Object],[object Object],[object Object]
Antimetabolites—— Folic Acid Antagonist ,[object Object],[object Object],[object Object],[object Object]
Antimetabolites—— Folic Acid Antagonist   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Antimetabolites—— Purine Antagonists ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antimetabolites—— Pyrimidine Antagonists ,[object Object],[object Object],[object Object]
Antimetabolites—— Pyrimidine Antagonists ,[object Object],[object Object],[object Object]
Antimetabolites—— Pyrimidine Antagonists ,[object Object],[object Object],[object Object],[object Object]
Antimetabolites—— Pyrimidine Antagonists ,[object Object],[object Object],[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anti-Cancer Plant Allaloids ,[object Object],[object Object]
Anti-Cancer Plant Allaloids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anti-Cancer Plant Allaloids ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Anti-Cancer Plant Allaloids
Platinum Compound ,[object Object],[object Object],[object Object]
Platinum Compound ,[object Object],[object Object],[object Object],[object Object],[object Object]
Platinum Compound ,[object Object],[object Object],[object Object]
Hormones ,[object Object],[object Object]
Hormones ,[object Object],[object Object],[object Object]
Hormones ,[object Object],[object Object]
Hormones ,[object Object],[object Object],[object Object]
Hormones ,[object Object],[object Object],[object Object],[object Object],[object Object]
Hormones ,[object Object],[object Object],[object Object]
Problems With Cancer Chemotherapy   ,[object Object],[object Object]
Drug Resistance   ,[object Object],[object Object],[object Object]
Drug Resistance ,[object Object],[object Object]
Drug Resistance   ,[object Object],[object Object]
Drug Resistance ,[object Object],[object Object],[object Object]
Drug Toxicity ,[object Object]
Immunomodulating Drugs ,[object Object],[object Object],[object Object]
Immunomodulating Drugs ,[object Object],[object Object],[object Object]
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Anti cancer drugs

  • 1. 抗癌药( Anti-Cancer Drugs ) 北京协和医学院基础医学院 药理学系 叶菜英
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  • 14. Growth Fraction (GF) GF = Proliferating cell group Total tumor cell group CCNSA : drugs that are active throughout the cell cycle. CCSA: drugs that act during a specific phase of the cell cycle.
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  • 23. The Long Road of a New Medicine
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