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Rigjenerimi i drejtuar kockor 
Dr. Geralda Himollari
C’eshte rigjenerimi? 
 Rigjenerimi: rigjenerimi eshte rritja dhe diferencimi i 
qelizave te reja dhe substancave intraqelizore per 
formimin e indeve te reja 
 Rigjenerimi i drejtuar indor: Metode per parandalimin 
e migrimit epitelial per gjate murit cementar te 
xhepit.
Objektivat per nje membrane-barriere ideale 
1. Duhet te jete biokompatibel dhe/ose te mundesoje 
integrimin indor. 
2. Nuk duhet te jete toxike dhe karcinogjene 
3. Duhet te jete kimikisht inert dhe joantigjenik 
4. Te perdoret lehte gjate manipulimit ne fazen 
kirurgjikale
…Objektivat per nje membrane-barriere 
ideale 
5. Duhet te jete mjaftushem rigide aq sa te ruaje nje 
hapesire midis saj dhe siperfaqes se rrenjes 
6. Te hiqet lehtesisht ne rast komplikacioni 
7. Te mos kete kosto te larte 
8. Te vendoset lehte dhe te kete jetegjatesi 
9. Duhet te pershtatet sipas situates klinike
Indikacionet 
1. Klasa e II e bifurkacioneve 
2. Difektet nenkockore 
3. Difektet e recesionit 
4. Augmentimi alveolar 
5. Riparimi i difekteve post nderhyrjeve 
6. Parandalimi i humbjes kockore vecanerisht kur mungon nje ose me 
shume mure. 
7. Rikonstruktimi i kockes alveolare atrofike gjate vendosjes se nje 
implanti
Kunderindikacionet 
1. Ne rastet kur vaskularizimi i lembos eshte i 
kompromentuar 
2. Difektet horizontale 
3. Ne rastet e perforimit te lembos 
4. Ne difekte shume minimale te periodonciumit
Klasifikimi i defektit 
A. Me i parashikueshmi 
 Ne bifurkacionet e Gr.II me sasi te madhe kocke interproximale 
 Ne difektet vertikale intrakockore me shume se 4-5 mm dhe perfshin 
2/3 e murit intrakockor. 
B. E moderuar: 
 Difekt ne 2 prej mureve 
 Bifurkacionet e klases se II maxillare meziale ose distale
…Klasifikimi i defektit 
C. E ulet: 
 Bifurkacionet e klases se III me sasi te larte kocke interproximale 
D. Me pak i parashikueshmi 
 Difekt horizontal kockor 
 Bifurkacion i klases se III me difekt horizontal kockor
Procedura kirurgjikale 
1. Incizioni 
2. Shkolitja 
3. Kyretimi 
4. Vendosja e graftit kockor 
5. Vendosja e membranes se pershtatshme 
6. Suturimi 
7. Heqja e materialit
Incizioni primar 
a. Incizionet intra sulkulare behen gjate preparimit per nje lembo 
te plote mukoperiostale 
b. Te gjithe xhepat reziduale epiteliale eleminohen per te lejuar 
integrimin midis e-PTFE dhe indeve lidhese te lembos 
c. Incizioni mund te shtrihet ne 1-2 dhembe mezialisht dhe/ose 
distalisht zones se trajtuar per te patur nje fushpamje me te 
qarte 
d. Nese eshte e nevojshme, incizioni vertikal mund te vendoset 
mezialisht
Preparimi i difektit 
 Pastrimi i difektit nga qelizat granulare 
 “Scaling & root planing” 
 Largimi i spikulave kockore dhe lemimi per 
stimulimin e rritjes se vaskularizimit dhe ate qelizor.
Zgjedhja dhe vendosja e materialit 
periodontal 
 Ruajtja ne kushte sterile e materialit 
 Zgjidhet masa e pershtatshme me difektin per ta 
mbuluar plotesisht ate. 
 Me ane te gershereve i jepet forma adekuate dhe 
shmanget lenia e pjeseve te mprehta
Materialet e sutures 
1. Sutura Gore-Tex rekomandohet ne vendosjen e 
materialit dhe mbylljen e lembos 
2. Suturat e mendafshit ose monofilamentet mund te 
perdoren per zonat ne largesi te materialit 
3. Suturat bioabsorbable nuk jane te rekomanduara
Teknikat e suturimit 
1. Suturimi sling perdoret per te afruar materialin mbi 
difekt pa ndihmen e lembos ose indeve 
2. Materiali duhet te pershtase ngushtesisht sip.e 
dhembit dhe ne te gjitha pikat per te parandaluar 
proliferimin epitelial midis dhembit dhe materialit 
duke ndihmuar keshtu edhe ne stabilizimin e plages 
3. Lemboja marginale  idealja eshte 2-3 mm koronal 
nga materiali
Teknikat e suturimit
Heqja e materialit 
1. Heqjen e materialit mund ta bejme 4-8 jave pas 
vendosjes ose ne cfaredo lloj kohe nese ndodh nje 
komplikacion serioz 
2. Nese materiali nuk mund te hiqet lehtesisht, 
rekomandohet nje incizion i mprehte
…Heqja e materialit 
3. Per heqjen e materialit perdorim nje pince 
anatomike 
4. Lemboja ripozicionohet serish mbi indet e reja dhe 
suturohet me suturat e mendafshit
Konsideratat post-operative 
 Shpelaresit e gojes – per 10 dite 
 Terapia me antibiotike (7-10 dite) 
 Tetracycline 250 mg q.i.d. 
 Dixycycline 100 mg b.i.d. 
 Veshjet periodontale jane ideale 
 Perdorimi i dental floss eshte mire te evitohet per sa 
kohe materiali eshte aty 
 Pacienti kontrollohet cdo jave nese ka expozim, nese jo 
cdo 2 jave 
 Materiali hiqet menjehere nese zhvillohet ndonje 
komplikacion
Konsideratat e zgjedhjes se membranes 
 Krijimi dhe ruajtja e nje hapesire te mjaftueshme 
nen barriere eshte nje faktor mjaft i rendesishem 
per nje rezutat te suksesshem 
 Integrimi indor 
 Biokompatibiliteti
Klasifikimi i membranave barriere 
 Membranat jo te rezorbueshme 
 Membranat e rezorbueshme
Membranat jo te rezorbueshme 
 e-PTFE (Expanded polytetrafluoroethlene ) 
- Goretex 
 PTFE (Non-expanded polytetrafluoroethlene) 
- Tef Gen-FD
…Membranat jo te rezorbueshme 
 Titanium-reinforced expanded 
polytetrafluoroethlene 
 Titanium membrane with microperforation 
- FRIOS® Bone shield
Membranat e rezorbueshme 
 Barrierat e kolagjenit 
- Bio-Guide, Bio-Mend, Colla Tape 
 Polimeret sintetike 
- Vicryl Mesh, Resolut, Resolut XT
…Membranat e rezorbueshme 
 Membranat biologjikisht aktive: 
Platelet-rich plasma 
 Materiale te tjera 
- Capset, Lambone
Avantazhet e membranes se 
titaniumit 
 Fixim efektiv te grafteve 
 Stabilitet mekanik optimal 
 Biokompatibilitet maximal 
 Fixohet lehte ne saje te tack-eve te membranes
Disavantazhet 
e membranes se Titaniumit 
 Rrit mundesine e ekspozimit me ane te 
perforimit mukozal 
 Duhen shmangur ngarkimet direkte me dhembe 
 Ndjeshmeri teknike
Konsideratat e perzgjedhjes se 
membranes 
 Membranat shume Flexibile nuk kane rigiditet te 
mjaftueshem 
 Nevojitet me teper membrane jo e rezorbueshme 
rigide
Rigjenerimi i lezionit
Gjendja fillestare
Zona per t’u rigjeneruar 
Trajtimi Endodontik
Vendosja e Emdogain
Bio-oss
Membrana Bio-gide
Suturimi
4 muaj postoperator
Faleminderit

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Rigjenerimi i Drejtuar Indor (GBR)

  • 1. Rigjenerimi i drejtuar kockor Dr. Geralda Himollari
  • 2. C’eshte rigjenerimi?  Rigjenerimi: rigjenerimi eshte rritja dhe diferencimi i qelizave te reja dhe substancave intraqelizore per formimin e indeve te reja  Rigjenerimi i drejtuar indor: Metode per parandalimin e migrimit epitelial per gjate murit cementar te xhepit.
  • 3. Objektivat per nje membrane-barriere ideale 1. Duhet te jete biokompatibel dhe/ose te mundesoje integrimin indor. 2. Nuk duhet te jete toxike dhe karcinogjene 3. Duhet te jete kimikisht inert dhe joantigjenik 4. Te perdoret lehte gjate manipulimit ne fazen kirurgjikale
  • 4. …Objektivat per nje membrane-barriere ideale 5. Duhet te jete mjaftushem rigide aq sa te ruaje nje hapesire midis saj dhe siperfaqes se rrenjes 6. Te hiqet lehtesisht ne rast komplikacioni 7. Te mos kete kosto te larte 8. Te vendoset lehte dhe te kete jetegjatesi 9. Duhet te pershtatet sipas situates klinike
  • 5. Indikacionet 1. Klasa e II e bifurkacioneve 2. Difektet nenkockore 3. Difektet e recesionit 4. Augmentimi alveolar 5. Riparimi i difekteve post nderhyrjeve 6. Parandalimi i humbjes kockore vecanerisht kur mungon nje ose me shume mure. 7. Rikonstruktimi i kockes alveolare atrofike gjate vendosjes se nje implanti
  • 6. Kunderindikacionet 1. Ne rastet kur vaskularizimi i lembos eshte i kompromentuar 2. Difektet horizontale 3. Ne rastet e perforimit te lembos 4. Ne difekte shume minimale te periodonciumit
  • 7. Klasifikimi i defektit A. Me i parashikueshmi  Ne bifurkacionet e Gr.II me sasi te madhe kocke interproximale  Ne difektet vertikale intrakockore me shume se 4-5 mm dhe perfshin 2/3 e murit intrakockor. B. E moderuar:  Difekt ne 2 prej mureve  Bifurkacionet e klases se II maxillare meziale ose distale
  • 8. …Klasifikimi i defektit C. E ulet:  Bifurkacionet e klases se III me sasi te larte kocke interproximale D. Me pak i parashikueshmi  Difekt horizontal kockor  Bifurkacion i klases se III me difekt horizontal kockor
  • 9. Procedura kirurgjikale 1. Incizioni 2. Shkolitja 3. Kyretimi 4. Vendosja e graftit kockor 5. Vendosja e membranes se pershtatshme 6. Suturimi 7. Heqja e materialit
  • 10. Incizioni primar a. Incizionet intra sulkulare behen gjate preparimit per nje lembo te plote mukoperiostale b. Te gjithe xhepat reziduale epiteliale eleminohen per te lejuar integrimin midis e-PTFE dhe indeve lidhese te lembos c. Incizioni mund te shtrihet ne 1-2 dhembe mezialisht dhe/ose distalisht zones se trajtuar per te patur nje fushpamje me te qarte d. Nese eshte e nevojshme, incizioni vertikal mund te vendoset mezialisht
  • 11.
  • 12. Preparimi i difektit  Pastrimi i difektit nga qelizat granulare  “Scaling & root planing”  Largimi i spikulave kockore dhe lemimi per stimulimin e rritjes se vaskularizimit dhe ate qelizor.
  • 13. Zgjedhja dhe vendosja e materialit periodontal  Ruajtja ne kushte sterile e materialit  Zgjidhet masa e pershtatshme me difektin per ta mbuluar plotesisht ate.  Me ane te gershereve i jepet forma adekuate dhe shmanget lenia e pjeseve te mprehta
  • 14. Materialet e sutures 1. Sutura Gore-Tex rekomandohet ne vendosjen e materialit dhe mbylljen e lembos 2. Suturat e mendafshit ose monofilamentet mund te perdoren per zonat ne largesi te materialit 3. Suturat bioabsorbable nuk jane te rekomanduara
  • 15. Teknikat e suturimit 1. Suturimi sling perdoret per te afruar materialin mbi difekt pa ndihmen e lembos ose indeve 2. Materiali duhet te pershtase ngushtesisht sip.e dhembit dhe ne te gjitha pikat per te parandaluar proliferimin epitelial midis dhembit dhe materialit duke ndihmuar keshtu edhe ne stabilizimin e plages 3. Lemboja marginale  idealja eshte 2-3 mm koronal nga materiali
  • 17. Heqja e materialit 1. Heqjen e materialit mund ta bejme 4-8 jave pas vendosjes ose ne cfaredo lloj kohe nese ndodh nje komplikacion serioz 2. Nese materiali nuk mund te hiqet lehtesisht, rekomandohet nje incizion i mprehte
  • 18. …Heqja e materialit 3. Per heqjen e materialit perdorim nje pince anatomike 4. Lemboja ripozicionohet serish mbi indet e reja dhe suturohet me suturat e mendafshit
  • 19.
  • 20.
  • 21.
  • 22.
  • 23. Konsideratat post-operative  Shpelaresit e gojes – per 10 dite  Terapia me antibiotike (7-10 dite)  Tetracycline 250 mg q.i.d.  Dixycycline 100 mg b.i.d.  Veshjet periodontale jane ideale  Perdorimi i dental floss eshte mire te evitohet per sa kohe materiali eshte aty  Pacienti kontrollohet cdo jave nese ka expozim, nese jo cdo 2 jave  Materiali hiqet menjehere nese zhvillohet ndonje komplikacion
  • 24. Konsideratat e zgjedhjes se membranes  Krijimi dhe ruajtja e nje hapesire te mjaftueshme nen barriere eshte nje faktor mjaft i rendesishem per nje rezutat te suksesshem  Integrimi indor  Biokompatibiliteti
  • 25. Klasifikimi i membranave barriere  Membranat jo te rezorbueshme  Membranat e rezorbueshme
  • 26. Membranat jo te rezorbueshme  e-PTFE (Expanded polytetrafluoroethlene ) - Goretex  PTFE (Non-expanded polytetrafluoroethlene) - Tef Gen-FD
  • 27. …Membranat jo te rezorbueshme  Titanium-reinforced expanded polytetrafluoroethlene  Titanium membrane with microperforation - FRIOS® Bone shield
  • 28. Membranat e rezorbueshme  Barrierat e kolagjenit - Bio-Guide, Bio-Mend, Colla Tape  Polimeret sintetike - Vicryl Mesh, Resolut, Resolut XT
  • 29. …Membranat e rezorbueshme  Membranat biologjikisht aktive: Platelet-rich plasma  Materiale te tjera - Capset, Lambone
  • 30.
  • 31. Avantazhet e membranes se titaniumit  Fixim efektiv te grafteve  Stabilitet mekanik optimal  Biokompatibilitet maximal  Fixohet lehte ne saje te tack-eve te membranes
  • 32. Disavantazhet e membranes se Titaniumit  Rrit mundesine e ekspozimit me ane te perforimit mukozal  Duhen shmangur ngarkimet direkte me dhembe  Ndjeshmeri teknike
  • 33. Konsideratat e perzgjedhjes se membranes  Membranat shume Flexibile nuk kane rigiditet te mjaftueshem  Nevojitet me teper membrane jo e rezorbueshme rigide
  • 34.
  • 35.
  • 36.
  • 39. Zona per t’u rigjeneruar Trajtimi Endodontik