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Aboubakr Elnashar
The surgical management of female SUI has been deeply changed when Ulmsten described a new concept in 1995: the mid-uretheral support without tension (TVT). 
In 2001, Delorme described a new approach (TOT) eliminating the complications related to the penetration of the retro-pubic space 
Aboubakr Elnashar
TVT procedures use a vertical, retropubic route. 
This intrapelvic route exposes the patient to a number of complications: 
bladder perforation 
injuries to blood vessels or GIT 
Aboubakr Elnashar
•TVT: By placing a prolene tape around the midurethera without tension Restores the pubourethral ligaments & the suburetheral vaginal wall Dynamic kinking of the midurthera at stress (Rezapour et al, 2001) 
•Corrects the central & lateral fascial defects of the anterior compartment of the vagina (Ursula et al,2000) 
Aboubakr Elnashar
TOT: The tape is placed under the mid- urethera (as in TVT) between the two obturator foramen, creating a real hammock supporting the urethera (uretheral suspension in TVT) (Delorme,2001). 
It is purely perineal & transverse 
The position of TOT is similar to that of natural hammock supporting the urethera 
Aboubakr Elnashar
1.Anticoagulant therapy (stop 14 d or replace with low dose heparin) 
2.Urinary tract infection 
3.No sexual intercourse, heavy lifting or exercise for 1mo 
Aboubakr Elnashar
1.Genuine SI. 
2.SI with Intrinsic sphincter deficiency (urethral p <20 cm H2O). 
3.Mixed I (urge & stress). 
4.Recurrent SI (previous traditional surgical procedure had failed). 
Aboubakr Elnashar
1.Pregnancy 
2.Women with plan for future pregnancy (prolene mesh will not stretch significantly). Incontinence may recur. 
3.Motor urge incontinence & significant detrusor instability (Ulmsten,2001) 
Aboubakr Elnashar
TVT: Ursula et al,2000: 8.7% in 1762 patients 
1. Bladder perforation: 5.4%. The most frequent complication 
2. De novo urgency or urge incontinence: 5.1% 
3. Retropubic haematoma: 0.8% 
Aboubakr Elnashar
4. Rare complications 
a.Anterior vaginal wall laceration 
b.Retained plastic sheath 
c.Obturator nerve irritation 
d.Vaginal wound infection Most of these complications are related to the penetration of the retropubic space 
Aboubakr Elnashar
TOT: 
Although the complications are uncommon, they must be kept in mind in order to adopt an appropriate strategy to prevent their development 
I. Costa et al (2004) 183 women 
Intraoperative: 2.2% (Up to 15% in TVT (Lebert et al, 2001) 
No vascular, nerve or bowel injury 
Bladder perforation: 1 
Uretheral perforation: 2 
Lateral vaginal perforation: 1 
All these complications disappeared with use of the index finger into the vaginal incision. 
Aboubakr Elnashar
Postoperative: 
1. De nevo urgency: 5% (from 0-20% in TVT, Peschers et al, 2000) 
2. Voiding disorders: 3.3% (7 women) 
{excessive tension of the tape} 
Treatment: 
immediate release of the tape in 3 (surgical 2, uretheral dilatation with Hegar 1) 
Temporary intermittent self-catheterization in 4 
Aboubakr Elnashar
3. Vaginal extrusion of the tape: {silicon part of the tape}. 
Obtape not contain silicon 
At 1 year 
80.5% were completely cured 
7.5% were improved 
Aboubakr Elnashar
II. Krauth et al,2005: 604 women 
Operative: very few 
0.5% vesical perforations, 
0.3% vaginal perforations, 
no urethral wounds, 
0.8% 200-300 ml haemorrhages, 
2 perineal haematomas (0.33%). 
Aboubakr Elnashar
Post-operative: 
1.5% transient retentions, 
2.3% transient pain, 
2.5% urinary infections, 
1.3% transient dysuria. 
Aboubakr Elnashar
After 3 mo 
5.2%: de novo symptoms. 
After one year: 
Satisfaction rate: 85.5% 
1.5%: de novo dysuria & urgency. 
Aboubakr Elnashar
III. But (2005): 
Vaginal wall erosion 6.7%: 6 weeks after surgery 
(Monarc) 
The greater prevalence of vginal wall erosion demand a search for the mechanism. 
Treatment: 
The periuretheral portion of the tape was removed & a new Prolene tape was placed through the retropubic space. 
Follow up after 3 months: No signs of erosion. 
Aboubakr Elnashar
Long term safety is not known, particularly in relation to 
changes in the synthetic material changes in bladder & uretheral behaviour 
as voiding disorders & bladder instability (Delorme,2004) 
Aboubakr Elnashar
I. De Tayrac et al (2004): 31 TVT & 30 TOT 
TOT 
TVT 
P 
Operative time 
Bladder injury 
Urinary retention 
Cure 
Improvement 
Failure 
15 min 
0.0 
13.3 
90% 
3.3% 
6.7% 
27 min 
9.7% 
25.8% 
83.9% 
9.7% 
6.5% 
S 
S 
S 
NS 
NS 
NS 
Aboubakr Elnashar
After 1-year: 
No vaginal erosion occurred in either of the groups. 
No differences were found in bladder outlet obstruction after TVT and T.O.T. 
CONCLUSION: T.O.T. appears to be equally efficient as TVT for treatment of SUI. 
Aboubakr Elnashar
II. Mellier et al (2004): 94 TOT & 99 TVT 
TOT 
TVT 
P 
Hgic complications 
Bladder injuries 
Uretheral injuries 
Cure rate 
2% 
0.0 
0.9% 
95% 
10% 
10% 
0.0% 
90% 
S 
S 
NS 
NS 
Aboubakr Elnashar
In conclusion: 
Obturator approach shows identical urinary results to the retropubic approach. 
Major hemorrhage and bowel perforation are excluded in the TOT procedure. 
Thus simplicity, safety and continence result mean that the obturator approach is the best method of suburethral tape insertion for the treatment of USI. 
Aboubakr Elnashar
1.TOT is a safe, effective technique for the treatment of female SUI. 
2.The easy technique, the short learning curve & the very high grade of satisfaction of the patient show that this approach is based upon effective anatomical & physiological criteria. 
Aboubakr Elnashar
E-mail: elnashar53@hotmail.com 
Aboubakr Elnashar

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TOT Procedure for SUI Management

  • 2. The surgical management of female SUI has been deeply changed when Ulmsten described a new concept in 1995: the mid-uretheral support without tension (TVT). In 2001, Delorme described a new approach (TOT) eliminating the complications related to the penetration of the retro-pubic space Aboubakr Elnashar
  • 3. TVT procedures use a vertical, retropubic route. This intrapelvic route exposes the patient to a number of complications: bladder perforation injuries to blood vessels or GIT Aboubakr Elnashar
  • 4. •TVT: By placing a prolene tape around the midurethera without tension Restores the pubourethral ligaments & the suburetheral vaginal wall Dynamic kinking of the midurthera at stress (Rezapour et al, 2001) •Corrects the central & lateral fascial defects of the anterior compartment of the vagina (Ursula et al,2000) Aboubakr Elnashar
  • 5. TOT: The tape is placed under the mid- urethera (as in TVT) between the two obturator foramen, creating a real hammock supporting the urethera (uretheral suspension in TVT) (Delorme,2001). It is purely perineal & transverse The position of TOT is similar to that of natural hammock supporting the urethera Aboubakr Elnashar
  • 6. 1.Anticoagulant therapy (stop 14 d or replace with low dose heparin) 2.Urinary tract infection 3.No sexual intercourse, heavy lifting or exercise for 1mo Aboubakr Elnashar
  • 7. 1.Genuine SI. 2.SI with Intrinsic sphincter deficiency (urethral p <20 cm H2O). 3.Mixed I (urge & stress). 4.Recurrent SI (previous traditional surgical procedure had failed). Aboubakr Elnashar
  • 8. 1.Pregnancy 2.Women with plan for future pregnancy (prolene mesh will not stretch significantly). Incontinence may recur. 3.Motor urge incontinence & significant detrusor instability (Ulmsten,2001) Aboubakr Elnashar
  • 9. TVT: Ursula et al,2000: 8.7% in 1762 patients 1. Bladder perforation: 5.4%. The most frequent complication 2. De novo urgency or urge incontinence: 5.1% 3. Retropubic haematoma: 0.8% Aboubakr Elnashar
  • 10. 4. Rare complications a.Anterior vaginal wall laceration b.Retained plastic sheath c.Obturator nerve irritation d.Vaginal wound infection Most of these complications are related to the penetration of the retropubic space Aboubakr Elnashar
  • 11. TOT: Although the complications are uncommon, they must be kept in mind in order to adopt an appropriate strategy to prevent their development I. Costa et al (2004) 183 women Intraoperative: 2.2% (Up to 15% in TVT (Lebert et al, 2001) No vascular, nerve or bowel injury Bladder perforation: 1 Uretheral perforation: 2 Lateral vaginal perforation: 1 All these complications disappeared with use of the index finger into the vaginal incision. Aboubakr Elnashar
  • 12. Postoperative: 1. De nevo urgency: 5% (from 0-20% in TVT, Peschers et al, 2000) 2. Voiding disorders: 3.3% (7 women) {excessive tension of the tape} Treatment: immediate release of the tape in 3 (surgical 2, uretheral dilatation with Hegar 1) Temporary intermittent self-catheterization in 4 Aboubakr Elnashar
  • 13. 3. Vaginal extrusion of the tape: {silicon part of the tape}. Obtape not contain silicon At 1 year 80.5% were completely cured 7.5% were improved Aboubakr Elnashar
  • 14. II. Krauth et al,2005: 604 women Operative: very few 0.5% vesical perforations, 0.3% vaginal perforations, no urethral wounds, 0.8% 200-300 ml haemorrhages, 2 perineal haematomas (0.33%). Aboubakr Elnashar
  • 15. Post-operative: 1.5% transient retentions, 2.3% transient pain, 2.5% urinary infections, 1.3% transient dysuria. Aboubakr Elnashar
  • 16. After 3 mo 5.2%: de novo symptoms. After one year: Satisfaction rate: 85.5% 1.5%: de novo dysuria & urgency. Aboubakr Elnashar
  • 17. III. But (2005): Vaginal wall erosion 6.7%: 6 weeks after surgery (Monarc) The greater prevalence of vginal wall erosion demand a search for the mechanism. Treatment: The periuretheral portion of the tape was removed & a new Prolene tape was placed through the retropubic space. Follow up after 3 months: No signs of erosion. Aboubakr Elnashar
  • 18. Long term safety is not known, particularly in relation to changes in the synthetic material changes in bladder & uretheral behaviour as voiding disorders & bladder instability (Delorme,2004) Aboubakr Elnashar
  • 19. I. De Tayrac et al (2004): 31 TVT & 30 TOT TOT TVT P Operative time Bladder injury Urinary retention Cure Improvement Failure 15 min 0.0 13.3 90% 3.3% 6.7% 27 min 9.7% 25.8% 83.9% 9.7% 6.5% S S S NS NS NS Aboubakr Elnashar
  • 20. After 1-year: No vaginal erosion occurred in either of the groups. No differences were found in bladder outlet obstruction after TVT and T.O.T. CONCLUSION: T.O.T. appears to be equally efficient as TVT for treatment of SUI. Aboubakr Elnashar
  • 21. II. Mellier et al (2004): 94 TOT & 99 TVT TOT TVT P Hgic complications Bladder injuries Uretheral injuries Cure rate 2% 0.0 0.9% 95% 10% 10% 0.0% 90% S S NS NS Aboubakr Elnashar
  • 22. In conclusion: Obturator approach shows identical urinary results to the retropubic approach. Major hemorrhage and bowel perforation are excluded in the TOT procedure. Thus simplicity, safety and continence result mean that the obturator approach is the best method of suburethral tape insertion for the treatment of USI. Aboubakr Elnashar
  • 23. 1.TOT is a safe, effective technique for the treatment of female SUI. 2.The easy technique, the short learning curve & the very high grade of satisfaction of the patient show that this approach is based upon effective anatomical & physiological criteria. Aboubakr Elnashar