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Amavata, rheumatiod arthritis, amavata treatment,

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amavata

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Amavata, rheumatiod arthritis, amavata treatment,

  1. 1. By- Dr K.RAGHU RAMUDU, 2nd year P.G Scholar Department of Dravyaguna S.V.Ayurvedic college,Tirupati, Andhra pradesh Review of Scientific studies on Amavata hara drugs Dr M. Paramkussh Rau M.D.(D.G),Ph.D. P.G.Professor& H.O.D. Department of Dravyaguna S.V.Ayurvedic college,Tirupati, Andhra pradesh
  2. 2. Introduction  Amavata is the most crippling of the joint diseases. It occurs throughout the world in all climates  First explained in Madhava Nidana, by Madhavakara.  Ama and vitiated Vata play the dominant role so it is called as Amavata  The incidence of Amavata (Rheumatoid Arthritis) is reported to be 1-2 % of general population with a female to male ratio of 3:1.
  3. 3. Nidana & Samprapthi Viruddahara means unwholesome foods or combination of foods which effects adversely. Poor digestion power, defective metabolism Sedentary life style and also too much exercise So affected defective metabolism with the influence of nervous system also affects the normal functioning, and the products of this reaches Dhamanis (blood vessels) and circulates all over the body and produces symptoms.
  4. 4. Samanya lakshanas Bodyache Poor appetite, feeling thirsty, lethargic Heavyness in the body Fever feeling Non inflammatory and no suppurative nature
  5. 5. Severe AMAVATA features  Very difficult to tolerate when becomes severe. Can also be considered as difficult to treat when aggravates  Severe pain in hand, foot, head, ankle, neck, low back, knee and hip joints  Pain and swelling is seen in different parts of body  Pain will be severe as if bit by scorpion. (burning sensation and pain as if hit by stick)
  6. 6. with the use of NSAID’s (Non Steroidal Anti Inflammatory Drugs), glucocorticoids, DMARD’s (Disease Modifying Anti Rheumatic Drugs), treatment remains unsatisfactory through modern system of medicine. Patients are continuously looking with a hope towards Ayurveda to overcome this challenge. So the Ayurvedic medicinal herbs are moving to mainstream
  7. 7. Pippali (Piper longum Linn.) Pippali is one of the Rasayana drugs described in Ayurveda. It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata, i.e. rheumatoid arthritis. Pippali alleviates Ama, the factor responsible for Balabhrmsha or development of autoimmune disorders in the body, resulting in the correction in immune system activities. Pippali has rasayana and immunomodulator actions. Thus, because of all these actions together, it plays an important role in the Samprapti-vighatana of the Amavata, i.e. rheumatoid arthritis. Ref : Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid Arthritis) Anamika Soni,1 Kalapi Patel,2 and S. N. Gupta3
  8. 8. Shunthi(Zingiber officinale Roscoe): Shunthi due to its Katu Rasa and Ushna Virya; is well known for Vata-Shleshma Vibandhahara. Shunthi possesses the basic quality of Deepan and Pachan properties, which improve Jatharagni When Jatharagni is improved, it leads to the formation of Dhatus and checks the formation of Ama. By virtue of Ushana Veerya, it digests and absorbs the vitiated Ama by its Shoshana Karma. Scientifically, it has been proved that Shunthi possesses active principles of gingerol, dehydrozingerone, and gingerdione, and they are potent inhibitors of prostaglandin synthesis, indicating the mechanism of an anti-arthritic effect. Ref: Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid arthritis Kishore, P., K.V. Devi Das and S. Banerjee
  9. 9. Guduchi(Tinospora cordifolia Willd.) : Guduchi possesses the qualities of Tikta, Kashaya Rasa, Madhur Vipak, and Ushana Veerya. Guduchi have the dual action of Vata Shamana and Bruhana, on the tissues, especially the Asthi Dhatu. Guduchi contains gycosides, whose activity resembles that of nonsteriodal anti-inflammatory agents producing anti-inflammatory and anti-arthritic activities. Ref : Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata Mhaiskar, V.B., D.C. Pandya and K.B. Karmarkar
  10. 10. Rasona(Allium cepa Linn): Rasona is a well-known Vata and Kaphahara. It is also proved to have an anti-inflammatory effect. A concentrate having allicin and allinase alkaloid proved effective in treating rheumatoid arthritis. Rasona is a rasayana according to Bhavprakash and Madanpal and thus it is very useful for treating the disease and also for maintaining the health of the patients due to the chronic nature of the disease. Ref : A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with special reference to Rheumatoid arthritis Raja Ram Mahto,1 Alankruta R. Dave,2 and V. D. Shukla3
  11. 11. Haridra(Curcuma longa Linn.): Curcuma longa, commonly known as Turmeric, has antiseptic and anti-inflammatory properties. Curcumin, an alkaloid isolated from this plant, has anti- inflammatory, anti-arthritic and anti-rheumatic properties. It also has beneficial effects on platelet aggregation and vascular prostaglandin synthesis. The activation of the adrenohypophysial axis may be responsible for inhibition of late arthritic changes. Ref ; Advances in research in Indian Medicine K.N Udupa, G.N Chaturvedi and S.N Tripathi
  12. 12. Dalbergia lanceolaria L. This is a tree of Leguminacae family found on the small hills throughout India. The botanical description of the plant is available in wealth of india and has also been described by Kirtikar and Basu. This plant is popularly used for the treatment of arthritis as folk medicine. The decoction of leaves and tender branches of the plant mixed with sugar and ghee is used every day for a month or so. The seed oil has also been described to have anti- Rheumatic property. Ref ; Advances in research in Indian Medicine K.N Udupa, G.N Chaturvedi and S.N Tripathi
  13. 13. Semecarpus anacardium Linn. (Bhallataka): It is tree of Anacardiacae family found in the lower level of Himalayan range. It is popularly known as Marking nut . This is one of the potent drugs of Indian system of medicine used for various conditions, it contains a highly irritant oil of Phenolic nature in the pulp of the fruit.
  14. 14. This drug is supposed to have powerful action on gastro-intestinal tract. It stimulates the digestive mechanism. According to ayurveda involvement of gastro-intestinal tract is primary in the aetiology of amavata., hence this drug was given a trial to assess its role in the treatment of the same. Ref : Bhallataka in management of rheumatoid arthritis (Amavata): A clinical and experimental evidence P Kishore, SN Tripathi - Rheumatism, 1966
  15. 15. Paedaria foetida Linn. (prasarini) It is a creeper of Rubiacae family having an special pungent odour. The root is quite thick which is used for medicinal purpose. Extensive experimental and clinical studies have been done on this drug the result have been highly encouraging. Oil processed with this drug has also been recommended for Rheumatic diseases. Ref ; Advances in research in Indian Medicine K.N Udupa, G.N Chaturvedi and S.N Tripathi
  16. 16. Ricinus communis Linn. (Erenda) Eranda oil by virtue of its different pharmacological property overcomes the pathology of amavata like ushna virya& vata pacifying property helps in improving pain and inflammation. Ushna property also acts as deepana and potentiates agni thus checking ama formation. Castor oil is very effective natural anti,inflammatory. High vitamin E content contributes significantly to the anti,Inflammatory properties of castor oil. The natural vitamin E present in castor oil has a number of tocopherol specific moisturizing, anti,inflammatory &anti,oxidant property. Also vitamin E contributes to improve microcirculation and UV protection. Ref : Effect Of Eranda Taila & Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar* , Rai NP
  17. 17. Commiphora mukul Hook.(Guggulu) The Sanskrit definition of the term "guggul" is "one that protects against diseases." This attests to the wide respect and therapeutic Ayurvedic applications for this botanical, considered the most important for the removal of "ama," toxic substances which accumulate as a result of sluggish digestion and circulation associated with a slowing of metabolism Guggul is a resin, the major ingredient in joint care and immuno care that has been regarded as a remedy in Ayurvedic medicine, known to increase white blood cell count and to possess strong immuno-modulating properties. Guggul is one of the "broad spectrum" health products with a wide range of benefits. Ref ; Advances in research in Indian Medicine K.N Udupa, G.N Chaturvedi and S.N Tripathi
  18. 18. References: 1.Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid Arthritis) Anamika Soni,1 Kalapi Patel,2 and S. N. Gupta3 2.A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with special reference to Rheumatoid arthritis Raja Ram Mahto,1 Alankruta R. Dave,2 and V. D. Shukla3 3.Effect Of Eranda Taila & Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar* , Rai NP 4.Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid arthritis Kishore, P., K.V. Devi Das and S. Banerjee 5.Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata Mhaiskar, V.B., D.C. Pandya and K.B. Karmarkar 6.Management of Amavata with ‘Amrita Ghrita’: A clinical study P. S. Lekurwale,1 Kamlesh Pandey,2 and P. Yadaiah3 7.Advances in research in Indian Medicine K.N Udupa, G.N Chaturvedi and S.N Tripathi 8.Mishra al. UPJ 2013,02 (04) : page20-22 9Panthulu Raghupathi Goud et al/IJRAP 3 (1) Jan-Feb 2013
  19. 19. ACKNOWLEDGEMENT : I am thankful to TTD, Principal S.V Ayurvedic college Tirupathi and my guide & Professor Dr M. Paramkussh Rau garu for kind support.
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