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Osteoarthritis
Osteoarthritis ,[object Object],[object Object],[object Object]
Factors responsible ,[object Object],[object Object],[object Object],[object Object]
Pathologic lesions ,[object Object],[object Object],[object Object]
Normal Cartilage ,[object Object],[object Object],[object Object]
Structure of Normal Cartilage ,[object Object],[object Object],[object Object],[object Object]
Structure of Normal Cartilage ,[object Object],[object Object],[object Object],[object Object],[object Object]
Structure of Normal Cartilage ,[object Object],[object Object],[object Object],[object Object]
Structure of Normal Cartilage ,[object Object],[object Object],[object Object],[object Object],[object Object]
Structure of Normal Cartilage ,[object Object],[object Object],[object Object]
Structure of Normal Cartilage
Function of Normal Cartilage ,[object Object],[object Object],[object Object]
Function of Normal Cartilage ,[object Object],[object Object],[object Object]
OA cartilage ,[object Object],[object Object]
Degenerative cartilage
Mechanisms responsible for degradation ,[object Object],[object Object]
Mechanisms responsible for degradation ,[object Object],[object Object],[object Object]
Synovial changes
Cytokines in OA ,[object Object],[object Object],[object Object]
Proinflammatory cytokines ,[object Object],[object Object]
TNF- α ,[object Object],[object Object],[object Object],[object Object]
IL-1 ,[object Object],[object Object],[object Object]
TNF- α and IL-1 ,[object Object],[object Object],[object Object],[object Object],[object Object]
IL-6 ,[object Object],[object Object],[object Object]
IL-8 ,[object Object],[object Object]
Leukemic inhibitory factor (LIF) ,[object Object],[object Object],[object Object]
Antiinflammatory cytokines ,[object Object],[object Object],[object Object]
IL-4 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IL-1Ra ,[object Object],[object Object],[object Object],[object Object]
IL-10, IL-13 ,[object Object],[object Object]
Osteoarthritis and Joint Replacement ,[object Object],[object Object],[object Object]
Knee Arthroplasty aka Total Knee Replacement (TKR)
Possible Side Effects of Knee Arthroplasty ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Knee Arthroplasty
Possible Side Effects of Hip Arthroplasty ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Hip Arthroplasty
[object Object],[object Object],[object Object],[object Object],[object Object],Hip Arthroplasty
Hip Fractures Usually Occurs @ the “Surgical Neck” of Femur Often results in disruption of blood flow….Avascular Necrosis * *
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Treatment of Hip Fracture
[object Object],[object Object],[object Object],[object Object],[object Object],Hip Fractures
Facts about Hip Fractures and Osteoporosis ,[object Object],[object Object],[object Object]
Risk of Hip Fracture and BMD
Facts about hip fractures and Osteoporosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Osteoarthritis