Hemophilia is a genetic bleeding disorder caused by mutations on the F8 gene located on the X chromosome. People with hemophilia experience prolonged bleeding from minor injuries due to a lack of clotting factor VIII or IX in their blood. Treatment involves replacement therapy through frequent injections of clotting factor concentrates. While treatment allows people with hemophilia to live normal lives, risks include developing antibodies against the clotting factor and bleeding complications. Researchers are studying gene therapy as a potential cure by correcting the defective genes that cause hemophilia.