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ANTERIOR CRUCIATE 
LIGAMENT-INJURY & 
MANAGEMENT
ANATOMY 
 ACL is composed of multiple collagen 
fascicles 
surrounded by an endotendineum which is 
grouped into fibers measuring around 
38mm in length (range 25 to 41 mm) and 
10 mm in width (range 7 to 12 mm) 
 Microspocially composed of interlacing fibrils 
(150 to 250 Nanometer in diamter) 
 synovial membrane envelope the ACL
 ORIGIN 
- From the posteromedial corner of medial 
aspect of 
lateral femoral condyle in the intercondylar 
notch 
 INSERTION 
- Fossa in front of & lateral to anterior spine 
of 
tibia
 ACL is composed of two principal parts 
1. Small Anteromedial band 
and 
2. Larger bulky posterolateral portion 
CLINICAL IMPORTANCE 
- Anteromedial bundle is tight in flexion and 
the 
posterolateral bundle is tight in extension 
- In extension both bundles are parallel 
- In flexion both bundles are crossed
Action 
These attachments allow the ACL to resist 
anterior translation and medial rotation of the 
tibia, in relation to the femur.
INNERVATION: 
- Tibal nerve( Infiltrates the capsule 
posteriorly) 
- Golgi tendon receptors 
BLOOD SUPPLY: 
- Major blood supply is from 
MIDDLE GENICULAR ARTERY 
Bony attachments do not provide a significant 
source of blood to distal or proximal ligaments
 ACL vascularization arises from the middle 
genicular artery and vessels of the infrapatella 
fat pad and adjacent synovium 
 The artery gives rise to periligamentous 
vessels which form a web-like network within 
the synovial membrane 
 These periligamentous vessels give rise to 
penetrating branches which transversely cross 
the ACL and anastomose with a network of 
longitudinally oriented endoligamentous 
vessels
 Terminal branches of the inferior medial and 
lateral genicular arteries supply the distal 
portion of the ACL directly. 
 The extremities of the ACL seem to be better 
vascularized than the middle part, and the 
proximal portion seems to have a greater 
vascular density than the distal portion
CAUSE OF ACL INJURY 
The anterior cruciate 
ligament can be injured 
in 
several ways 
 Changing direction 
rapidly 
 Stopping suddenly 
 Slowing down while 
running 
 Landing from a jump 
incorrectly 
 Direct contact or 
collision, such as a 
football tackle
 Several studies have shown 
that female athletes have a 
higher incidence of ACL injury 
than male athletes because of 
Differences in 
- Physical conditioning 
- Muscular strength 
- Neuromuscular control 
- pelvis and lower extremity 
(leg) alignment 
and 
- the effects of estrogen on 
ligament properties.
 ACL injuries occur in combination with 
damage to 
-The meniscus 
-Articular cartilage or 
-Other ligaments 
 Secondary damage may occur in patients who 
have 
repeated episodes of instability due to ACL 
injury.
 With chronic instability, up to 90 percent of 
patients will have meniscus damage when 
reassessed 10 or more years after the initial 
injury. 
 Similarly, the prevalence of articular cartilage 
lesions increases up to 70 percent in patients 
who have a 10-year-old ACL deficiency
GRADING 
 Partial tears of the anterior cruciate ligament 
are 
rare 
 Most ACL injuries are complete or near 
complete tears 
 Injured ligaments are considered "sprains" and 
are graded on a severity scale.
 Grade 1 Sprains. 
The ligament is mildly damaged . It has been 
slightly stretched, but is still able to keep the knee 
joint stable. 
 Grade 2 Sprains. 
The ligament is stretched to the point where it 
becomes loose. This is often referred to as a 
partial tear of the ligament. 
 Grade 3 Sprains. 
This type of sprain is most commonly referred to 
as a complete tear of the ligament. The ligament 
has been split into two pieces, and the knee joint 
is unstable.
SYMPTOMS 
 When ACL is injured , pt might hear a 
"popping" 
noise. 
 Other typical symptoms include: 
-Pain with swelling. 
-Loss of full range of motion 
-Tenderness along the joint line 
-Discomfort while walking
PHYSICAL EXAMINATION 
INCLUDE 
 ANTERIOR DRAWER TEST 
 LACHMAN’S TEST 
 PIVOT SHIFT TEST 
 KT-2000 ARTHROMETER TEST
ANTERIOR DRAWER TEST 
 To perform anterior drawer test, examiner 
grasps pt's tibia & pulls it forward when the 
affected leg is flexed at 90 degree while noting 
degree of anterior tibial displacement
LACHMAN’S TEST 
 This is a variant of the anterior drawer test 
 The examination is carried out with the knee in 15 deg 
of 
flexion, and external rotation (relaxes IT band) 
 For a right knee, the examiner's right hand grips the 
inner 
aspect of the calf and the left hand grasps outer aspect 
of 
the distal thigh 
 Attempt to quantify the displacement in mm is done by 
comparing this displacement to the normal side
 End point should be graded as hard or soft 
- End point is said to be hard when the 
ACL 
abruptly halts the forward motion of the tibia 
on 
the femur 
- End point is soft when there is no ACL & 
restraints are more elastic secondary 
stabilizers;
PIVOT SHIFT TEST 
 During this test, 
pt is kept in supine & examiner holds pt's leg with 
both hands 
abduct the pt’s hip (to relax the ITB and allow the 
tibia to rotate) 
Holding the heel in one hand and applying a valgus 
stress in the other hand, the 
knee is slowly flexed
 The tibia, as well as the valgus, subluxes 
easily if anterior force is applied. 
 After the anterior subluxation of the tibia is 
noticed, the knee is slowly flexed, and the tibia 
will reduce with a snap at about 20° to 30°of 
flexion.
INVESTIGATIONS 
 MRI 
 Arthroscopy
INVESTIGATION
TREATMENT 
 NON-SURGICAL METHOD 
 SURGICAL METHOD
 Immediately after injury 
R.I.C.E (Rest Ice Compression Elevation () 
 Non surgical treatment 
Exercise (after swelling decreases and weight-bearing 
progresses) 
Braces 
 Rehabilitation Brace 
 Functional Brace
Nonsurgical Treatment 
 Nonsurgical management is indicated in 
patients with 
- partial tears and no instability symptoms 
- complete tears and no symptoms of knee 
instability 
- Who do light manual work or live sedentary 
lifestyles 
- Whose growth plates are still open (children)
Precautions 
 Modification of active lifestyle to avoid high 
demand activities 
 Muscle strengthening exercises for life 
 May require knee brace 
 Despite above precautions ,secondary 
damage to knee cartilage & meniscus leading 
to premature arthritis
Surgical Treatment 
 Timing of Surgery 
 1) Swelling in the knee must go down to near-normal 
levels 
 2) Range-of-motion (bending and straightening) 
of the injured knee must be nearly equal to the 
uninjured knee 
 3) Good Quadriceps muscle strength must be 
present. 
 Usually it takes a couple of weeks after injury 
before ACL reconstruction can be performed. 
 The presence of any associated injuries to the 
knee joint involving cartilage, meniscus, or other 
ligaments may change the time-frame for surgery.
Surgical Treatment 
 ACL tears are not usually repaired using 
suture to 
sew it back together, because repaired ACLs 
have 
generally been shown to fail over time 
 Therefore, the torn ACL is generally replaced 
by a 
substitute graft made of tendon
The grafts commonly used to replace the ACL 
include 
autograft Allograft 
 Patellar tendon 
 Hamstring tendon 
 Quadriceps 
tendon 
 patellar tendon, 
 Achilles tendon, 
 semitendinosus, 
 gracilis, or posterior 
tibialis tendon
 Patients treated with surgical reconstruction of 
the 
ACL have long-term success rates of 82 %- 
95% 
 The goal of the ACL reconstruction surgery is 
to prevent instability and restore the function of 
the torn ligament, creating a stable knee. 
 Recurrent instability and graft failure are seen 
in
PATIENT CONSIDERATIONS 
 Active adult patients involved in sports or jobs 
that 
require pivoting, turning or hard-cutting as well 
as 
heavy manual work are encouraged to 
consider 
surgical treatment. 
 Activity, not age, should determine if surgical 
intervention should be considered.
 In young children or adolescents with ACL 
tears, 
early ACL reconstruction creates a possible 
risk of 
growth plate injury, leading to bone growth 
problems. The surgeon can delay ACL surgery 
until 
the child is closer to skeletal maturity or the 
surgeon 
may modify the ACL surgery technique to
 A patient with a torn ACL and significant 
functional 
instability has a high risk of developing 
secondary 
knee damage and should therefore consider 
ACL 
reconstruction. 
 It is common to see ACL injuries combined 
with 
damage to the menisci (50 %), articular
Surgical Choices 
1.PATELLAR TENDON AUTOGRAFT. 
 The middle third of the patellar tendon of the patient, 
along 
with a bone plug from the shin and the patella is used 
in the 
patellar tendon autograft. Occasionally referred to by 
some 
surgeons as the "gold standard" for ACL 
reconstruction, 
recommended for high-demand athletes and patients 
whose 
jobs do not require a significant amount of kneeling.
 In addition, most studies show equal or better 
outcomes in terms of postoperative tests for 
knee 
laxity (Lachman's, anterior drawer and 
instrumented 
tests) when this graft is compared to others.
The Disadvantages of the patellar tendon 
autograft are: 
-Postoperative patello femoral pain 
-Pain with kneeling 
-increased risk of postoperative stiffness 
-risk of patella fracture 
-Quadriceps Weakness 
-Persistent Tendon Defect
2.Hamstring tendon autograft. 
 The semitendinosus hamstring tendon on 
the inner 
side of the knee is used in creating the 
hamstring 
tendon autograft for ACL reconstruction. 
 Some use an additional tendon, the gracilis, 
which 
is attached below the knee in the same area.
 Hamstring graft proponents claim there are 
fewer 
problems associated with harvesting of the 
graft 
compared to the patellar tendon autograft 
including: 
- Fewer problems with anterior knee pain 
after surgery 
- Less postoperative stiffness problems 
- Smaller incision
 The graft function may be limited by the strength 
and 
type of fixation in the bone tunnels, as the graft 
does 
not have bone plugs. 
 There have been conflicting results in research 
studies 
as to whether hamstring grafts are slightly more 
susceptible to graft elongation (stretching), which 
may 
lead to increased laxity during objective 
testing. Recently,
 There are some indications that patients who 
have 
intrinsic ligamentous laxity and knee 
hyperextension 
of 10 degrees or more may have increased risk 
of 
postoperative hamstring graft laxity on clinical 
exam. 
Therefore, some clinicians recommend the use 
of 
patellar tendon autografts in these hypermobile
 chronic or 
residual medial collateral ligament laxity 
(grade 2 or more) at the time of ACL 
reconstruction may be a contra-indication 
for 
use of the patient's own semitendinosus 
and 
gracilis tendons as an ACL graft.
3.QUADRICEPS TENDON AUTOGRAFT. 
 The quadriceps tendon autograft is often used 
for 
patients who have already failed 
ACL reconstruction. 
 Middle third of the patient's quadriceps tendon 
and 
a bone plug from the upper end of the patella 
are used.
 This yields a larger graft for taller and heavier 
patients. Because there is a bone plug on one 
side 
only, the fixation is not as solid as for the 
patellar 
tendon graft. 
 There is a high association with postoperative 
anterior knee pain and a low risk of patella 
fracture. Patients may find the incision is not 
cosmetically appealing
ALLOGRAFTS. 
 Allografts are grafts taken from cadavers and are 
becoming increasingly popular. 
 These grafts are also used for patients who have 
failed 
ACL reconstruction before and in surgery to repair 
or 
reconstruct more than one knee ligament. 
 Advantages of using allograft tissue include 
- Elimination of pain caused by obtaining the 
graft
The PATELLAR TENDON ALLOGRAFT 
allows for strong bony fixation in the tibial and 
femoral bone 
tunnels with screws.
 However, allografts are associated with 
- Risk of infection, including viral 
transmission (HIV and Hepatitis C) 
There have also been conflicting results in 
research studies as to whether allografts are 
slightly more susceptible to graft elongation 
(stretching), which may lead to increased laxity 
during testing.
 Recently published literature may point to a 
higher failure rate with the use of allografts for 
ACL reconstruction. 
 Failure rates ranging from 23% to 34.4% have 
been reported in young, active patients 
returning to high-demand sporting activities 
after ACL reconstruction with allografts. 
 This is compared to autograft failure rates 
ranging from 5% to 10%.
Meta-analysis of Patellar vs. 
Hamstring tendons in ACL 
reconstruction 
 •Controlled trials with minimum 2 year follow-up• 
Evaluated; return to pre-injury level of 
activity, KT testing, Lachmanscores, pivot shift 
scores, ROM, complications, failures•4 studies 
fulfilled inclusion criteria•B-T-B showed a 
>20% chance return to pre-injury activity level 
versus hamstring, (p value = 0.01) 
 Yunes, M. et al “Patellar Versus Hamstring 
Tendons in ACL reconstruction; A Meta-analysis” 
Arthroscopy Vol. 17, No. 3 (March) 
2001; pp248-257
Synthetic Grafts 
 The best scenario for the use of the synthetic 
graft is when the 
 graft can be buried in soft tissue, such as in 
extra-articular reconstruction. 
 This allows for collagen ingrowth and ensures 
the long-term viability of the synthetic graft. 
 It will be sure to fail early if it is laid into a joint 
bare, especially going around tunnel edges, 
and is unprotected by soft tissue.
 Disadvantages 
 The main disadvantage is that all the long-term 
studies have shown high failure rate. There is the 
potential for reaction to the graft material with 
synovitis, as seen with the use of the Gore-Tex graft. 
 With the Gore-Tex graft, there was also the increased 
risk of late hematogenous joint infection. 
 The results that have been reported with the use of 
the Gore-Tex 
graft suggest that it should not be used for ACL 
reconstruction. 
Unacceptable failure rates have also been reported 
with the use of the Stryker Dacron ligament and the 
Leeds-Keio ligament.
` GRAFT FIXATION
Ultimate load to failure of femoral fixation 
devices. 
 Mitek 600N 
 BioScrew 400N 
 Endo-button: tape 500N 
 BioScrew: Endo-pearl 700N 
 Bone mulch screw 900N 
 Cross pin 900N 
 Endo-button with closed loop tape 1300N
Interference Fit Screws 
Advantages 
 Quick, familiar, and easy to use. 
 Direct bone to tendon healing, with Sharpey’s fibers at the 
tunnel 
aperture. 
 Less tunnel enlargement. 
 Disadvantages 
 The disadvantages are as follows: 
 Longer graft preparation time. 
 Bone quality dependent. 
 Damage to the graft with the screw. 
 Divergent screw has poor fixation. 
 Removal of metal screw makes revision difficult
Interference screw 
 Biodegradable 
 Metalic
Inteference Screw
Cross-Pin Fixation 
Advantages 
 The advantages are as follows: 
 Strongest tested fixation. 
 May individually tension all bundles of graft. 
Disadvantages 
 The disadvantages are as follows: 
 Pin may tilt in soft bone and lose fixation. 
 Steep learning curve of fiddle factor. 
 Special guides are required.
Transfix
Crosspin/transfix
Endobutton 
 The EB is a small oval button that anchors the graft against 
the outer femoral cortex. 
 The Endobutton (EB) is the most widely used femoral fixation 
device worldwide that is designed specifically for soft tissue 
grafts. 
 Pioneered by Dr. Thomas Rosenberg and introduced around 
1990, it was the first device specifically designed to hold soft 
tissue grafts. 
 As originally designed, the surgeon would tie a Dacron tape 
connecting the button to the tendon. 
 In the past 5 years, this technique has been largely 
supplanted by use of the EB-CL (continuous loop), which 
obviates the need to tie knots. 
 Due to the longevity of the device, there is a much greater 
literature concerning it than any of the other newer, soft 
tissue–specific devices.
ENDOBUTTON 
Advantages 
 The Endo-button with closed loop tape is strong, 
 The plastic button is cheap, available and easy to 
do 
Disadvantages 
 Fixation site is distant with increase in laxity, with 
the bungee cord effect. 
 Increased in tunnel widening. 
 Plastic button has low pullout strength, dependent 
on the sutures
Endobuttom Loop
 Clinical Results 
 In the largest meta-analysis of anterior cruciate 
ligament reconstruction (ACLR) autografts, the 
EB-hamstring combination was found to have 
the highest stability rates of any graft-fixation 
construct when paired with modern tibial 
fixation.Morbidity has been minimal.
 Milagro (Beta-Tricalcium Phosphate, 
Polylactide Co-Glycolide Biocomposite) 
The Milagro screw can be used for femoral or 
tibial fixation for soft tissue or bone–tendon– 
bone (BTB) autografts or allografts. It is 
available in various diameters from 7 to 12mm 
and in 23-, 30-, and 35-mm lengths. The 
Milagro screw is made from a polymer 
composite, Biocryl Rapide.
 EZLoc Femoral Fixation of a Soft Tissue Graft 
 The EZLoc (Arthrotek, Warsaw, IN) is a cortical 
femoral fixation device for a soft tissue anterior 
cruciate ligament (ACL) reconstruction that combines 
superior fixation properties (high resistance to 
slippage, infinite stiffness, and 1427N strength) with a 
simple surgical technique. 
 The EZLoc consists of a deployable lever arm 
connected to an axle in a slotted body through which 
the ACL graft is looped. 
 The EZLoc comes sterilely package with a sharp-tip 
passing pin that is secured in the slotted body with a 
suture tied under tension. The passing pin is passed 
through the tunnels, the gold lever arm is positioned 
lateral, and the soft tissue graft is looped through the 
slot in the EZLoc.
Tibial Fixing Devices 
Ultimate load to failure of tibial fixation devices. 
 Single staple 100N 
 Double staple 500N 
 Screw post 600N 
 Button 400N 
 RCI 300N 
 BioScrew 400N 
 BioScrew and button 600N 
 Intrafix 700N 
 Screw and washer 800N 
 Washer Loc 900N
One bundle or two bundle 
ACL reconstruction
 What is an “Anatomic” ACL reconstruction? 
 Every person is different; some people are short, 
others are tall. Similarly, each person has a 
different size and shape of the ACL. In order to 
properly reconstruct the ACL it is important to 
reproduce each persons individual anatomy. 
 The goals of anatomic ACL reconstruction are to: 
 Restore 60 – 80% of normal ACL anatomy 
 Regain stability and return to pre-injury activity 
level 
 Maintain long term knee health
 What is anatomic Double-Bundle ACL 
reconstruction? 
 In a “double-bundle” ACL reconstruction, the 
ACL is restored using two bundles. Just like 
the normal ACL, there will be an AM and a PL 
bundle. 
 In a “single-bundle” reconstruction, the ACL is 
restored using one bundle. There are some 
benefits of a “double-bundle” reconstruction, 
when compared to a “single-bundle”
 Anatomic double-bundle reconstruction better 
restores knee stability compared to single-bundle 
reconstruction. 
 Because anatomic double-bundle 
reconstruction uses two bundles to restore the 
ACL, it allows for a replacement of a larger 
size ACL
Pre requisite for single-bundle/ 
double-bundle 
reconstruction 
 An ACL insertion site greater than 18 mm 
allows for double-bundle reconstruction. 
 If the insertion site is less than 14 mm, there is 
only space available for a single-bundle 
procedure. 
 Between 14 – 18 mm, we can perform either 
double- or single-bundle reconstruction.
Indications for single bundle 
recon. 
 The patient is still growing and his or her 
growth plate is not closed. 
 The patient has severe arthritis of the knee. 
 The patient has multiple knee ligament injuries 
or a knee dislocation and multiple other 
ligaments need to be reconstructed at the 
same time. 
 The patient has bone that is severely bruised. 
 The patient has a small Intercondylar“notch”.
 A prospective comparative cohort study was carried 
out with 72 consecutive patients with chronic ACL 
deficiency to compare three ACL reconstruction 
procedures using hamstring tendon grafts. 
 The first 24 patients underwent a single-bundle 
procedure using a six-strand hamstring tendon graft. 
 The next 24 patients underwent a nonanatomical 
double-bundle procedure using four-strand and two-strand 
hamstring tendon grafts. 
 The final 24 patients underwent the anatomical 
double-bundle procedure using the same four-strand 
and two-strand hamstring tendon grafts. All 72 
patients underwent postoperative management with 
the same rehabilitation protocol.There were no 
significant differences among the background factors.
Conclusion 
 The postoperative anterior laxity measured 
was significantly less after the anatomical 
double-bundle reconstruction than after the 
single-bundle reconstruction. Concerning the 
results of the pivot-shift test
 Outcome of Arthroscopic Single-Bundle Versus 
Double-Bundle Reconstruction of the Anterior 
Cruciate Ligament: A Preliminary 2-Year 
Prospective Study 
 Se-Jin Park, M.D., Young-Bok Jung, M.D., Hwa- 
Jae Jung, M.D., Ho-Joong Jung, M.D., Hun Kyu 
Shin, M.D., Eugene Kim, M.D., Kwang-Sup Song, 
M.D., Gwang-Sin Kim, M.D., Hye-Young Cheon, 
P.A., Seonwoo Kim, Ph.D.Received: December 
29, 2008; Accepted: September 9, 2009; 
Published Online: February 22, 2010 
 ArthroscopyVolume 26, Issue 5, Pages 630–636, 
May 2010
 113 were included in this study. They serially 
obtained clinical and radiologic data 
preoperatively and postoperatively. They 
compared preoperative data and data at 2 years 
postoperatively in patients who had undergone 
single-bundle ACL reconstruction versus patients 
who had undergone double-bundle ACL 
reconstruction. 
 There were 50 single-bundle reconstructions and 
63 double-bundle reconstructions. Anteroposterior 
stability was assessed objectively by anterior 
stress radiographs with the telos device (telos, 
Marburg, Germany) and the maximal manual test
Conclusions 
 Double-bundle reconstruction of the ACL by a 
method using 2 femoral tunnel and 2 tibial 
tunnels showed no differences in stability 
results or any other clinical aspects or in terms 
of patient satisfaction.
COMPLICATIONS
Skeletally immature patients 
 Anterior cruciate ligament injuries in skeletally 
immature adolescents are being diagnosed 
with increasing frequency. 
 Nonoperative management of midsubstance 
ACL injuries in adolescent athletes frequently 
results in a high incidence of giving-way 
episodes, recurrent meniscal tears, and early 
onset of osteoarthritis
 The concern about ACL reconstruction in the 
athlete with open growth plates is that there 
will be 
 premature fusion of the plate, growth arrest, 
and potential for angular deformities.
Skeletally immature patients 
 Non surgical methods 
or 
 surgical methods
Non surgical method 
 In some less active individuals with mild-to-moderate 
instability, reduction of activity level 
may be all that is necessary until they have 
had an appropriate growth spurt and maturing 
of the physes. 
 Muscle strengthening exercises 
 knee brace 
 Away from sports activities
TRANSEPIPHYSEAL REPLACEMENT OF 
ANTERIOR CRUCIATE LIGAMENT USING 
QUADRUPLE HAMSTRING GRAFTS 
 The transepiphyseal replacement of anterior 
cruciate ligament using quadruple hamstring 
grafts 
 procedure described by Anderson is indicated in 
patients in Tanner stage I, II, or III of development. 
 The procedure is contraindicated in patients in 
Tanner stage IV of development, who can have 
conventional anterior cruciate ligament 
reconstruction 
 The tunnels are drilled centrally through the 
epiphysis and fixed with a button on the periosteal 
surface. There are no reported growth deformities
Anderson transepiphyseal replacement of 
anterior cruciate ligament using quadruple 
hamstring grafts
physeal-sparing, combined intraarticular 
and extraarticular reconstruction of acl by Kocher, 
Garg, and Micheli
Anterior Cruciate Ligament Reconstruction 
in Skeletally Immature Patients With 
Transphyseal Tunnels 
 Lauren H. Redler, M.D., Rebecca T. Brafman, 
B.A., Natasha Trentacosta, M.D., Christopher S. 
Ahmad, M.D.(Department of Orthopaedic Surgery, 
Columbia University Medical Center, New York, 
New York, U.S.A.) 
 Arthroscopy Volume 28, Issue 11, Pages 1710– 
1717, November 2012 
 Moises Cohen, M.D., Ph.D., Mario Ferretti, M.D., 
Ph.D., Marcelo Quarteiro, M.D., Frank B. 
Marcondes, M.D., João P.B. de Hollanda, 
M.D., Joicemar T. Amaro, M.D., Rene J. Abdalla, 
M.D., Ph.D.(Orthopedic Sports Medicine Division, 
Department of Orthopaedic Surgery and 
Traumatology, Universidade Federal de São 
Paulo–Escola Paulista de Medicina, São Paulo, 
Brazil)
Conclusions 
 ACL reconstruction by use of the transphyseal 
technique in an immature skeleton with a 
hamstring autograft, with careful attention 
being paid to the technique, resulted in good 
clinical outcomes and no growth abnormalities.

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Anterior cruciate ligament-Injury & management

  • 2. ANATOMY  ACL is composed of multiple collagen fascicles surrounded by an endotendineum which is grouped into fibers measuring around 38mm in length (range 25 to 41 mm) and 10 mm in width (range 7 to 12 mm)  Microspocially composed of interlacing fibrils (150 to 250 Nanometer in diamter)  synovial membrane envelope the ACL
  • 3.  ORIGIN - From the posteromedial corner of medial aspect of lateral femoral condyle in the intercondylar notch  INSERTION - Fossa in front of & lateral to anterior spine of tibia
  • 4.  ACL is composed of two principal parts 1. Small Anteromedial band and 2. Larger bulky posterolateral portion CLINICAL IMPORTANCE - Anteromedial bundle is tight in flexion and the posterolateral bundle is tight in extension - In extension both bundles are parallel - In flexion both bundles are crossed
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10. Action These attachments allow the ACL to resist anterior translation and medial rotation of the tibia, in relation to the femur.
  • 11. INNERVATION: - Tibal nerve( Infiltrates the capsule posteriorly) - Golgi tendon receptors BLOOD SUPPLY: - Major blood supply is from MIDDLE GENICULAR ARTERY Bony attachments do not provide a significant source of blood to distal or proximal ligaments
  • 12.  ACL vascularization arises from the middle genicular artery and vessels of the infrapatella fat pad and adjacent synovium  The artery gives rise to periligamentous vessels which form a web-like network within the synovial membrane  These periligamentous vessels give rise to penetrating branches which transversely cross the ACL and anastomose with a network of longitudinally oriented endoligamentous vessels
  • 13.  Terminal branches of the inferior medial and lateral genicular arteries supply the distal portion of the ACL directly.  The extremities of the ACL seem to be better vascularized than the middle part, and the proximal portion seems to have a greater vascular density than the distal portion
  • 14. CAUSE OF ACL INJURY The anterior cruciate ligament can be injured in several ways  Changing direction rapidly  Stopping suddenly  Slowing down while running  Landing from a jump incorrectly  Direct contact or collision, such as a football tackle
  • 15.
  • 16.  Several studies have shown that female athletes have a higher incidence of ACL injury than male athletes because of Differences in - Physical conditioning - Muscular strength - Neuromuscular control - pelvis and lower extremity (leg) alignment and - the effects of estrogen on ligament properties.
  • 17.  ACL injuries occur in combination with damage to -The meniscus -Articular cartilage or -Other ligaments  Secondary damage may occur in patients who have repeated episodes of instability due to ACL injury.
  • 18.  With chronic instability, up to 90 percent of patients will have meniscus damage when reassessed 10 or more years after the initial injury.  Similarly, the prevalence of articular cartilage lesions increases up to 70 percent in patients who have a 10-year-old ACL deficiency
  • 19. GRADING  Partial tears of the anterior cruciate ligament are rare  Most ACL injuries are complete or near complete tears  Injured ligaments are considered "sprains" and are graded on a severity scale.
  • 20.  Grade 1 Sprains. The ligament is mildly damaged . It has been slightly stretched, but is still able to keep the knee joint stable.  Grade 2 Sprains. The ligament is stretched to the point where it becomes loose. This is often referred to as a partial tear of the ligament.  Grade 3 Sprains. This type of sprain is most commonly referred to as a complete tear of the ligament. The ligament has been split into two pieces, and the knee joint is unstable.
  • 21. SYMPTOMS  When ACL is injured , pt might hear a "popping" noise.  Other typical symptoms include: -Pain with swelling. -Loss of full range of motion -Tenderness along the joint line -Discomfort while walking
  • 22. PHYSICAL EXAMINATION INCLUDE  ANTERIOR DRAWER TEST  LACHMAN’S TEST  PIVOT SHIFT TEST  KT-2000 ARTHROMETER TEST
  • 23. ANTERIOR DRAWER TEST  To perform anterior drawer test, examiner grasps pt's tibia & pulls it forward when the affected leg is flexed at 90 degree while noting degree of anterior tibial displacement
  • 24. LACHMAN’S TEST  This is a variant of the anterior drawer test  The examination is carried out with the knee in 15 deg of flexion, and external rotation (relaxes IT band)  For a right knee, the examiner's right hand grips the inner aspect of the calf and the left hand grasps outer aspect of the distal thigh  Attempt to quantify the displacement in mm is done by comparing this displacement to the normal side
  • 25.  End point should be graded as hard or soft - End point is said to be hard when the ACL abruptly halts the forward motion of the tibia on the femur - End point is soft when there is no ACL & restraints are more elastic secondary stabilizers;
  • 26. PIVOT SHIFT TEST  During this test, pt is kept in supine & examiner holds pt's leg with both hands abduct the pt’s hip (to relax the ITB and allow the tibia to rotate) Holding the heel in one hand and applying a valgus stress in the other hand, the knee is slowly flexed
  • 27.  The tibia, as well as the valgus, subluxes easily if anterior force is applied.  After the anterior subluxation of the tibia is noticed, the knee is slowly flexed, and the tibia will reduce with a snap at about 20° to 30°of flexion.
  • 28.
  • 29. INVESTIGATIONS  MRI  Arthroscopy
  • 31.
  • 32. TREATMENT  NON-SURGICAL METHOD  SURGICAL METHOD
  • 33.  Immediately after injury R.I.C.E (Rest Ice Compression Elevation ()  Non surgical treatment Exercise (after swelling decreases and weight-bearing progresses) Braces  Rehabilitation Brace  Functional Brace
  • 34. Nonsurgical Treatment  Nonsurgical management is indicated in patients with - partial tears and no instability symptoms - complete tears and no symptoms of knee instability - Who do light manual work or live sedentary lifestyles - Whose growth plates are still open (children)
  • 35. Precautions  Modification of active lifestyle to avoid high demand activities  Muscle strengthening exercises for life  May require knee brace  Despite above precautions ,secondary damage to knee cartilage & meniscus leading to premature arthritis
  • 36. Surgical Treatment  Timing of Surgery  1) Swelling in the knee must go down to near-normal levels  2) Range-of-motion (bending and straightening) of the injured knee must be nearly equal to the uninjured knee  3) Good Quadriceps muscle strength must be present.  Usually it takes a couple of weeks after injury before ACL reconstruction can be performed.  The presence of any associated injuries to the knee joint involving cartilage, meniscus, or other ligaments may change the time-frame for surgery.
  • 37. Surgical Treatment  ACL tears are not usually repaired using suture to sew it back together, because repaired ACLs have generally been shown to fail over time  Therefore, the torn ACL is generally replaced by a substitute graft made of tendon
  • 38. The grafts commonly used to replace the ACL include autograft Allograft  Patellar tendon  Hamstring tendon  Quadriceps tendon  patellar tendon,  Achilles tendon,  semitendinosus,  gracilis, or posterior tibialis tendon
  • 39.  Patients treated with surgical reconstruction of the ACL have long-term success rates of 82 %- 95%  The goal of the ACL reconstruction surgery is to prevent instability and restore the function of the torn ligament, creating a stable knee.  Recurrent instability and graft failure are seen in
  • 40. PATIENT CONSIDERATIONS  Active adult patients involved in sports or jobs that require pivoting, turning or hard-cutting as well as heavy manual work are encouraged to consider surgical treatment.  Activity, not age, should determine if surgical intervention should be considered.
  • 41.  In young children or adolescents with ACL tears, early ACL reconstruction creates a possible risk of growth plate injury, leading to bone growth problems. The surgeon can delay ACL surgery until the child is closer to skeletal maturity or the surgeon may modify the ACL surgery technique to
  • 42.  A patient with a torn ACL and significant functional instability has a high risk of developing secondary knee damage and should therefore consider ACL reconstruction.  It is common to see ACL injuries combined with damage to the menisci (50 %), articular
  • 43. Surgical Choices 1.PATELLAR TENDON AUTOGRAFT.  The middle third of the patellar tendon of the patient, along with a bone plug from the shin and the patella is used in the patellar tendon autograft. Occasionally referred to by some surgeons as the "gold standard" for ACL reconstruction, recommended for high-demand athletes and patients whose jobs do not require a significant amount of kneeling.
  • 44.  In addition, most studies show equal or better outcomes in terms of postoperative tests for knee laxity (Lachman's, anterior drawer and instrumented tests) when this graft is compared to others.
  • 45. The Disadvantages of the patellar tendon autograft are: -Postoperative patello femoral pain -Pain with kneeling -increased risk of postoperative stiffness -risk of patella fracture -Quadriceps Weakness -Persistent Tendon Defect
  • 46. 2.Hamstring tendon autograft.  The semitendinosus hamstring tendon on the inner side of the knee is used in creating the hamstring tendon autograft for ACL reconstruction.  Some use an additional tendon, the gracilis, which is attached below the knee in the same area.
  • 47.  Hamstring graft proponents claim there are fewer problems associated with harvesting of the graft compared to the patellar tendon autograft including: - Fewer problems with anterior knee pain after surgery - Less postoperative stiffness problems - Smaller incision
  • 48.  The graft function may be limited by the strength and type of fixation in the bone tunnels, as the graft does not have bone plugs.  There have been conflicting results in research studies as to whether hamstring grafts are slightly more susceptible to graft elongation (stretching), which may lead to increased laxity during objective testing. Recently,
  • 49.  There are some indications that patients who have intrinsic ligamentous laxity and knee hyperextension of 10 degrees or more may have increased risk of postoperative hamstring graft laxity on clinical exam. Therefore, some clinicians recommend the use of patellar tendon autografts in these hypermobile
  • 50.  chronic or residual medial collateral ligament laxity (grade 2 or more) at the time of ACL reconstruction may be a contra-indication for use of the patient's own semitendinosus and gracilis tendons as an ACL graft.
  • 51. 3.QUADRICEPS TENDON AUTOGRAFT.  The quadriceps tendon autograft is often used for patients who have already failed ACL reconstruction.  Middle third of the patient's quadriceps tendon and a bone plug from the upper end of the patella are used.
  • 52.  This yields a larger graft for taller and heavier patients. Because there is a bone plug on one side only, the fixation is not as solid as for the patellar tendon graft.  There is a high association with postoperative anterior knee pain and a low risk of patella fracture. Patients may find the incision is not cosmetically appealing
  • 53.
  • 54.
  • 55. ALLOGRAFTS.  Allografts are grafts taken from cadavers and are becoming increasingly popular.  These grafts are also used for patients who have failed ACL reconstruction before and in surgery to repair or reconstruct more than one knee ligament.  Advantages of using allograft tissue include - Elimination of pain caused by obtaining the graft
  • 56. The PATELLAR TENDON ALLOGRAFT allows for strong bony fixation in the tibial and femoral bone tunnels with screws.
  • 57.  However, allografts are associated with - Risk of infection, including viral transmission (HIV and Hepatitis C) There have also been conflicting results in research studies as to whether allografts are slightly more susceptible to graft elongation (stretching), which may lead to increased laxity during testing.
  • 58.  Recently published literature may point to a higher failure rate with the use of allografts for ACL reconstruction.  Failure rates ranging from 23% to 34.4% have been reported in young, active patients returning to high-demand sporting activities after ACL reconstruction with allografts.  This is compared to autograft failure rates ranging from 5% to 10%.
  • 59. Meta-analysis of Patellar vs. Hamstring tendons in ACL reconstruction  •Controlled trials with minimum 2 year follow-up• Evaluated; return to pre-injury level of activity, KT testing, Lachmanscores, pivot shift scores, ROM, complications, failures•4 studies fulfilled inclusion criteria•B-T-B showed a >20% chance return to pre-injury activity level versus hamstring, (p value = 0.01)  Yunes, M. et al “Patellar Versus Hamstring Tendons in ACL reconstruction; A Meta-analysis” Arthroscopy Vol. 17, No. 3 (March) 2001; pp248-257
  • 60. Synthetic Grafts  The best scenario for the use of the synthetic graft is when the  graft can be buried in soft tissue, such as in extra-articular reconstruction.  This allows for collagen ingrowth and ensures the long-term viability of the synthetic graft.  It will be sure to fail early if it is laid into a joint bare, especially going around tunnel edges, and is unprotected by soft tissue.
  • 61.  Disadvantages  The main disadvantage is that all the long-term studies have shown high failure rate. There is the potential for reaction to the graft material with synovitis, as seen with the use of the Gore-Tex graft.  With the Gore-Tex graft, there was also the increased risk of late hematogenous joint infection.  The results that have been reported with the use of the Gore-Tex graft suggest that it should not be used for ACL reconstruction. Unacceptable failure rates have also been reported with the use of the Stryker Dacron ligament and the Leeds-Keio ligament.
  • 63. Ultimate load to failure of femoral fixation devices.  Mitek 600N  BioScrew 400N  Endo-button: tape 500N  BioScrew: Endo-pearl 700N  Bone mulch screw 900N  Cross pin 900N  Endo-button with closed loop tape 1300N
  • 64. Interference Fit Screws Advantages  Quick, familiar, and easy to use.  Direct bone to tendon healing, with Sharpey’s fibers at the tunnel aperture.  Less tunnel enlargement.  Disadvantages  The disadvantages are as follows:  Longer graft preparation time.  Bone quality dependent.  Damage to the graft with the screw.  Divergent screw has poor fixation.  Removal of metal screw makes revision difficult
  • 65. Interference screw  Biodegradable  Metalic
  • 66.
  • 68. Cross-Pin Fixation Advantages  The advantages are as follows:  Strongest tested fixation.  May individually tension all bundles of graft. Disadvantages  The disadvantages are as follows:  Pin may tilt in soft bone and lose fixation.  Steep learning curve of fiddle factor.  Special guides are required.
  • 71. Endobutton  The EB is a small oval button that anchors the graft against the outer femoral cortex.  The Endobutton (EB) is the most widely used femoral fixation device worldwide that is designed specifically for soft tissue grafts.  Pioneered by Dr. Thomas Rosenberg and introduced around 1990, it was the first device specifically designed to hold soft tissue grafts.  As originally designed, the surgeon would tie a Dacron tape connecting the button to the tendon.  In the past 5 years, this technique has been largely supplanted by use of the EB-CL (continuous loop), which obviates the need to tie knots.  Due to the longevity of the device, there is a much greater literature concerning it than any of the other newer, soft tissue–specific devices.
  • 72. ENDOBUTTON Advantages  The Endo-button with closed loop tape is strong,  The plastic button is cheap, available and easy to do Disadvantages  Fixation site is distant with increase in laxity, with the bungee cord effect.  Increased in tunnel widening.  Plastic button has low pullout strength, dependent on the sutures
  • 74.  Clinical Results  In the largest meta-analysis of anterior cruciate ligament reconstruction (ACLR) autografts, the EB-hamstring combination was found to have the highest stability rates of any graft-fixation construct when paired with modern tibial fixation.Morbidity has been minimal.
  • 75.  Milagro (Beta-Tricalcium Phosphate, Polylactide Co-Glycolide Biocomposite) The Milagro screw can be used for femoral or tibial fixation for soft tissue or bone–tendon– bone (BTB) autografts or allografts. It is available in various diameters from 7 to 12mm and in 23-, 30-, and 35-mm lengths. The Milagro screw is made from a polymer composite, Biocryl Rapide.
  • 76.  EZLoc Femoral Fixation of a Soft Tissue Graft  The EZLoc (Arthrotek, Warsaw, IN) is a cortical femoral fixation device for a soft tissue anterior cruciate ligament (ACL) reconstruction that combines superior fixation properties (high resistance to slippage, infinite stiffness, and 1427N strength) with a simple surgical technique.  The EZLoc consists of a deployable lever arm connected to an axle in a slotted body through which the ACL graft is looped.  The EZLoc comes sterilely package with a sharp-tip passing pin that is secured in the slotted body with a suture tied under tension. The passing pin is passed through the tunnels, the gold lever arm is positioned lateral, and the soft tissue graft is looped through the slot in the EZLoc.
  • 77. Tibial Fixing Devices Ultimate load to failure of tibial fixation devices.  Single staple 100N  Double staple 500N  Screw post 600N  Button 400N  RCI 300N  BioScrew 400N  BioScrew and button 600N  Intrafix 700N  Screw and washer 800N  Washer Loc 900N
  • 78. One bundle or two bundle ACL reconstruction
  • 79.
  • 80.  What is an “Anatomic” ACL reconstruction?  Every person is different; some people are short, others are tall. Similarly, each person has a different size and shape of the ACL. In order to properly reconstruct the ACL it is important to reproduce each persons individual anatomy.  The goals of anatomic ACL reconstruction are to:  Restore 60 – 80% of normal ACL anatomy  Regain stability and return to pre-injury activity level  Maintain long term knee health
  • 81.  What is anatomic Double-Bundle ACL reconstruction?  In a “double-bundle” ACL reconstruction, the ACL is restored using two bundles. Just like the normal ACL, there will be an AM and a PL bundle.  In a “single-bundle” reconstruction, the ACL is restored using one bundle. There are some benefits of a “double-bundle” reconstruction, when compared to a “single-bundle”
  • 82.  Anatomic double-bundle reconstruction better restores knee stability compared to single-bundle reconstruction.  Because anatomic double-bundle reconstruction uses two bundles to restore the ACL, it allows for a replacement of a larger size ACL
  • 83. Pre requisite for single-bundle/ double-bundle reconstruction  An ACL insertion site greater than 18 mm allows for double-bundle reconstruction.  If the insertion site is less than 14 mm, there is only space available for a single-bundle procedure.  Between 14 – 18 mm, we can perform either double- or single-bundle reconstruction.
  • 84. Indications for single bundle recon.  The patient is still growing and his or her growth plate is not closed.  The patient has severe arthritis of the knee.  The patient has multiple knee ligament injuries or a knee dislocation and multiple other ligaments need to be reconstructed at the same time.  The patient has bone that is severely bruised.  The patient has a small Intercondylar“notch”.
  • 85.
  • 86.
  • 87.  A prospective comparative cohort study was carried out with 72 consecutive patients with chronic ACL deficiency to compare three ACL reconstruction procedures using hamstring tendon grafts.  The first 24 patients underwent a single-bundle procedure using a six-strand hamstring tendon graft.  The next 24 patients underwent a nonanatomical double-bundle procedure using four-strand and two-strand hamstring tendon grafts.  The final 24 patients underwent the anatomical double-bundle procedure using the same four-strand and two-strand hamstring tendon grafts. All 72 patients underwent postoperative management with the same rehabilitation protocol.There were no significant differences among the background factors.
  • 88. Conclusion  The postoperative anterior laxity measured was significantly less after the anatomical double-bundle reconstruction than after the single-bundle reconstruction. Concerning the results of the pivot-shift test
  • 89.  Outcome of Arthroscopic Single-Bundle Versus Double-Bundle Reconstruction of the Anterior Cruciate Ligament: A Preliminary 2-Year Prospective Study  Se-Jin Park, M.D., Young-Bok Jung, M.D., Hwa- Jae Jung, M.D., Ho-Joong Jung, M.D., Hun Kyu Shin, M.D., Eugene Kim, M.D., Kwang-Sup Song, M.D., Gwang-Sin Kim, M.D., Hye-Young Cheon, P.A., Seonwoo Kim, Ph.D.Received: December 29, 2008; Accepted: September 9, 2009; Published Online: February 22, 2010  ArthroscopyVolume 26, Issue 5, Pages 630–636, May 2010
  • 90.  113 were included in this study. They serially obtained clinical and radiologic data preoperatively and postoperatively. They compared preoperative data and data at 2 years postoperatively in patients who had undergone single-bundle ACL reconstruction versus patients who had undergone double-bundle ACL reconstruction.  There were 50 single-bundle reconstructions and 63 double-bundle reconstructions. Anteroposterior stability was assessed objectively by anterior stress radiographs with the telos device (telos, Marburg, Germany) and the maximal manual test
  • 91. Conclusions  Double-bundle reconstruction of the ACL by a method using 2 femoral tunnel and 2 tibial tunnels showed no differences in stability results or any other clinical aspects or in terms of patient satisfaction.
  • 93. Skeletally immature patients  Anterior cruciate ligament injuries in skeletally immature adolescents are being diagnosed with increasing frequency.  Nonoperative management of midsubstance ACL injuries in adolescent athletes frequently results in a high incidence of giving-way episodes, recurrent meniscal tears, and early onset of osteoarthritis
  • 94.  The concern about ACL reconstruction in the athlete with open growth plates is that there will be  premature fusion of the plate, growth arrest, and potential for angular deformities.
  • 95. Skeletally immature patients  Non surgical methods or  surgical methods
  • 96. Non surgical method  In some less active individuals with mild-to-moderate instability, reduction of activity level may be all that is necessary until they have had an appropriate growth spurt and maturing of the physes.  Muscle strengthening exercises  knee brace  Away from sports activities
  • 97. TRANSEPIPHYSEAL REPLACEMENT OF ANTERIOR CRUCIATE LIGAMENT USING QUADRUPLE HAMSTRING GRAFTS  The transepiphyseal replacement of anterior cruciate ligament using quadruple hamstring grafts  procedure described by Anderson is indicated in patients in Tanner stage I, II, or III of development.  The procedure is contraindicated in patients in Tanner stage IV of development, who can have conventional anterior cruciate ligament reconstruction  The tunnels are drilled centrally through the epiphysis and fixed with a button on the periosteal surface. There are no reported growth deformities
  • 98. Anderson transepiphyseal replacement of anterior cruciate ligament using quadruple hamstring grafts
  • 99. physeal-sparing, combined intraarticular and extraarticular reconstruction of acl by Kocher, Garg, and Micheli
  • 100. Anterior Cruciate Ligament Reconstruction in Skeletally Immature Patients With Transphyseal Tunnels  Lauren H. Redler, M.D., Rebecca T. Brafman, B.A., Natasha Trentacosta, M.D., Christopher S. Ahmad, M.D.(Department of Orthopaedic Surgery, Columbia University Medical Center, New York, New York, U.S.A.)  Arthroscopy Volume 28, Issue 11, Pages 1710– 1717, November 2012  Moises Cohen, M.D., Ph.D., Mario Ferretti, M.D., Ph.D., Marcelo Quarteiro, M.D., Frank B. Marcondes, M.D., João P.B. de Hollanda, M.D., Joicemar T. Amaro, M.D., Rene J. Abdalla, M.D., Ph.D.(Orthopedic Sports Medicine Division, Department of Orthopaedic Surgery and Traumatology, Universidade Federal de São Paulo–Escola Paulista de Medicina, São Paulo, Brazil)
  • 101. Conclusions  ACL reconstruction by use of the transphyseal technique in an immature skeleton with a hamstring autograft, with careful attention being paid to the technique, resulted in good clinical outcomes and no growth abnormalities.