Leishmaniasis is an infection caused by parasites of the Leishmania genus, which are transmitted through the bite of infected sand flies. It exists in three main forms: visceral leishmaniasis, which affects internal organs; cutaneous leishmaniasis, which causes skin sores; and mucosal leishmaniasis, affecting the mucous membranes of the nose and mouth. The parasite has a life cycle alternating between an insect vector like sand flies and a mammalian host like humans. Diagnosis involves microscopic examination of tissues or cultures to look for the parasite, and treatment depends on the form but may include antimonial drugs, amphotericin B, or miltefosine.