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Herbal cosmetics seminar

challenges during formulating herbal cosmetics

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Herbal cosmetics seminar

  1. 1. CHALLENGES IN FORMULATING HERBAL COSMETICS Presented By:- Kajal Pradhan M.Pharm Sem-2 Pharmaceutics 1
  2. 2. WHAT IS HERBAL COSMETICS? Herbal cosmetics are the preparations consisting of one or more herbs or processed herb(s) in specified quantities to provide specific cosmetic benefits. 2
  3. 3. 3  Quality Issues: Adulteration, misidentification of plant, faulty collection and preparation, incorrect formulation process are the main problems that reduces the effectiveness of herbal preparation and can be considered as key factors affecting quality and purity of herbal medicines.
  4. 4.  Admixture :Refers to addition of one article to another through accident, ignorance or carelessness.Eg: Stem portions are mixed along with leaf in drugs like –Bala; Dhattura; Clove is mixed along with leaves and petioles.Non-removal of undesirable parts or structures e.g. cork should be removed from ginger rhizome.  Proper drying conditions should be adhered. Improper drying may lead to unintentional adulteration e.g. if digitalis leaves are dried above 65 °C decomposition of glycosides by enzymatic hydrolysis. 4
  5. 5. 5
  6. 6.  Processing And Harvesting Issues: Indiscriminate harvesting, poor agriculture and propagation method, poor pre and post harvest practices, lack of processing techniques leads to the substandard quality of herbal drugs.  Deterioration happens especially during storage, leading to the loss of the active ingredients, production of metabolites with no activity and, in extreme cases, the production of toxic metabolites. Physical factors such as air (oxygen), humidity, light, and temperature can bring about deterioration directly or indirectly. 6
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  8. 8. 8  Quality Control Related Issues: Standardization, poor quality control procedure and lack of Good Manufacturing Practices (GMP) are the main hurdle to maintain the quality of herbal drugs.  Lack of awareness regarding the guideline among growers and manufacturers, lack of implementation and regulation of the guideline are also frequent in small and medium scale industries.
  9. 9.  Administrative Issues: Lack of regulation and controlling authority in herbal sector, lack of proper monitoring and controlling are absolute need for the quality of drugs.  Infrastructure Related Issue: Lack of processing technique, trained personal, sophisticated instrument, utilization of modern techniques, facility to fabricate instrument locally are the major problems. 9
  10. 10.  Pharmacovigilance: Proper pharmacovigilance in herbal sector is the need of time to find the toxicological data and adverse drug reaction of herbal drugs. Adverse reactions, contraindications, interactions with other drug, food and existing orthodox pharmaceuticals need to be monitor properly. 10
  11. 11.  Clinical Trial: Since the safety continues to be a foremost issue with the use of herbal remedies therefore, clinical trials are necessary to understand the safety and efficacy of these drugs before introduced them in global market.  Irrational Use: It is generally believed that herbal products don't have any side effects, interaction, but unfortunately is not true.Thus, irrational practice of these drugs can lead to various problems which can hinder the promotion of such drugs. 11
  12. 12.  R&D: Research and development on dosage, processing, techniques are the key need for any drug, but in herbal sector it is quite less compare to allopathic medicine.  Although in recent years, the trend is changing. Research to understand the mode of action and pharmacokinetics phenomenon, improvement/creation of monographs and reference standards for marker-based analysis are necessary of time.  Decisive gap in current Ethnopharmacological and modern medicinal plant research is another problem for sustainable, socio-culturally equitable and safe supply of herbal medicines. 12
  13. 13.  Collection Of Raw Material:  Raw materials obtained from different place with varying climate cannot be treated as same as there arises difference in herbal potency.  Collection of raw plant materials is the first step of performing there search and also the first difficulty to confront. It is the first important step which can lead to the wrong result at the end . This is because location and time of collection of medicinal plants have high impact on the bioassay screening results.  It is difficult to prepare reproducible plant extracts or preparations because the chemical compositions in the plants are affected by many factors, including the climate and soil. 13
  14. 14.  Other Issues: Unethical practice of herbal medicine, lack of qualified physician, exposure of unreliable and misleading information, lack of sufficient fund, absence of focused marketing and branding, lack of knowledge sharing also hold back the global promotion of herbal medicine. Lack of protection of biodiversity and protecting the traditional medicinal plants are also a big challenge. 14
  15. 15. MARKETED FORMULATION 15
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challenges during formulating herbal cosmetics

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