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PSORIASIS – AYURVEDIC MANAGEMENT
Vaidya Ruchi Gulati,
MD(Ayu)
SukhAyurveda 1
OVERVIEW
5. Summary
2
4. Managing psoriasis
3. Diagnosing psoriasis
2. Clinical presentation
1. Introduction
WHAT IS PSORIASIS?
 Inflammatory and
hyperplastic disease of
skin
 Characterised by
erythema and elevated
scaly plaques
 Chronic, relapsing
condition
 Course of disease often
unpredictable
3
PSORIASIS
4
EPIDEMIOLOGY
 Common skin disorder
 Prevalence variable: ~ 0.3–2.5%
 Prevalence equal in males and females
 Estimated incidence: ~ 60 per 100,000 per year
5
AGE OF ONSET
 Mean age: ~ 23–37 years
 Current theory:
2 distinct peaks with possible genetic
associations
 Early onset (16–22 years)
 More severe and extensive
 More likely to have affected first-degree family member
 Late onset (57–60 years)
 Milder form
 Affected first-degree family members nearly absent
6
PSORIASIS IS A T-CELL MEDIATED, AUTOIMMUNE
DISEASE1
Current hypothesis:
 Unknown skin antigens stimulate immune response
 Antigen-specific memory T-cells are primary
mediators
 Leads to impaired differentiation and
hyperproliferation of keratinocytes
7
COMMON TRIGGER FACTORS FOR PSORIASIS
 Infections (e.g. streptococcal, viral)
 Skin trauma (Koebner phenomenon)
 Psychological stress
 Drugs (e.g. lithium, beta blockers)
 Sunburn
 Metabolic factors (e.g. calcium deficiency)
 Hormonal factors (e.g. pregnancy)
8
SAMPRAPTI
Mind
(Stress)
Lifestyle
(Diet/
Relationships/
Daily Routine
/Seasonal
Routine)
Impact
on the
body
(Alters
Immune
System)
Psoriasis
(Excessive
Skin
production)
9
CLINICAL PRESENTATION:
CLASSIC PSORIASIS
 Well-defined and
sharply
demarcated
 Round/oval-
shaped lesions
 Usually
symmetrical
 Erythematous,
raised plaques
 Covered by
white, silvery
scales
10
COMMON SITES AFFECTED BY PSORIASIS
 Can affect any
part of the body
–
typically scalp,
elbow, knees and
sacrum
 Extent of disease
varies
1 11
PSYCHOSOCIAL IMPACT
12
TYPES OF PSORIASIS
 Chronic plaque
 Guttate
 Flexural
 Erythrodermic
 Pustular
 Localised and generalised
 Local forms
 Palmoplantar
 Scalp
 Nail (psoriatic
onychodystrophy)
13
CHRONIC PLAQUE PSORIASIS
 Most common type –
affects approximately
85%
 Features pink, well-
defined plaques with
silvery scale
 Lesions may be single or
numerous
 Plaques may involve
large areas of skin
 Classically affects elbows,
knees, buttocks and scalp
14
CHRONIC PLAQUE PSORIASIS
15
CHRONIC PLAQUE PSORIASIS
16
CHRONIC PLAQUE PSORIASIS
17
CHRONIC PLAQUE PSORIASIS
18
GUTTATE PSORIASIS
 Numerous and small
lesions – ~ 1 cm diameter
 Pink with less scale than
plaque psoriasis
 Commonly found on trunk
and proximal limbs
 Typically seen in
individuals < 30 years
 Often preceded by an
upper respiratory tract
streptococcal infection
1. 19
FLEXURAL PSORIASIS
 Lesions in skin folds
articularly groin,
gluteal cleft, axillae
and submammary
regions
 Often minimal or
absent scaling
 May cause diagnostic
difficulty when genital
or perianal region is
affected in isolation
1 20
ERYTHRODERMIC PSORIASIS
 Generalised erythema
covering entire skin surface
 May evolve slowly from
chronic plaque psoriasis or
appear as eruptive
phenomenon
 Patients may become
febrile, hypo/hyperthermic
and dehydrated
 Complications include
cardiac failure, infections,
malabsorption and
anaemia
 Relatively uncommon
21
PUSTULAR PSORIASIS
 Two forms:
 Localised form
 More common
 Presents as deep-seated
lesions with multiple small
pustules on palms and
soles
 Generalised form
 Uncommo Associated with
fever and widespread
pustules across the body
 inflamed body surface
22
PALMOPLANTAR PSORIASIS
 Can be
hyperkeratotic or
pustular
 May mimic dermatitis
– look for psoriatic
manifestations
elsewhere to aid
diagnosis
 Possibly aggravated
by trauma
23
SCALP PSORIASIS
 Varies from minor
scaling with erythema
to thick
hyperkeratotic
plaques
 May extend beyond
hairline
 Patient scratching
may produce
asymmetric plaques
24
NAIL PSORIASIS
 May be present in patients
with any type of psoriasis
 Can take several forms:
 Pitting: discrete, well-
circumscribed depressions
on nail surface
 Subungual hyperkeratosis:
silvery white crusting under
free edge of nail with some
thickening of nail plate
 Onycholysis: nail separates
from nail bed at free edge
 ‘Oil-drop sign’: pink/red
colour change on nail
surface
25
NAIL PSORIASIS
26
PSORIATIC ARTHRITIS
 Approximately 5–20%
have associated arthritis
 Five major patterns of
psoriatic arthritis:
 Distal interphalangeal
involvement
 Symmetrical polyarthritis
 Psoriatic
spondylarthropathy
 Arthritis mutilans
 Oligoarticular,
asymmetrical arthritis
 Clinical expressions
often overlap
27
DIAGNOSING PSORIASIS
 Other dermatological disorders
can resemble psoriasis
 Diagnosed clinically according to
appearance, distribution, history of lesions
and family history
 Important to consider non-cutaneous
complications
28
DIFFERENTIAL DIAGNOSIS
 Localised
patches/plaques
 Tinea
 Eczema
 Superficial basal cell
carcinoma and Bowen’s
disease
 Seborrhoeic dermatitis
 Cutaneous T-cell
lymphoma (mycosis
fungoides)
 Guttate
 Pityriasis rosea
 Drug eruption
 Secondary syphilis
 Flexural
 Tinea
 Eczema
 Candidiasis
 Seborrhoeic dermatitis
 Erythrodermic
 Eczema
 Cutaneous T-cell
lymphoma
 Pityriasis rubra pilaris
 Lichen planus
 Drug
 Palmoplantar
 Tinea
29
CLINICAL APPROACH
 Dosha chikitsa -Vatakapha/kapha/vata/pitta
 Dushya chikitsa -Rasa, Rakta Prasadana
 Avasthanusara Chikitsa -Saama/Niraama
-Navina/ Jirna
 Vyadhi pratyaneeka chikitsa
 Manobala vardhaka chikitsa
 Rasayana(Naimittika)
30
MANAGING PSORIASIS
 Goals of management
 Tailor management to individual and address both
medical and psychological aspects
 Improve quality of life
 Achieve long-term remission and disease control
 Minimise drug toxicity
 Evaluate and monitor efficacy and suitability of individual
treatments
 Remain flexible and respond to changing needs
31
MANAGING PSORIASIS
 Before starting treatment
 Establish relationship of trust with patient
 Provide patient with information
 Emphasise benign nature of disease
 Explain that psoriasis tends to be chronic and
recurrent
32
TREATING PSORIASIS:
GENERAL MEASURES
 Reduce/eliminate potential trigger factors:
 Stress
 Smoking
 Alcohol
 Trauma
 Drugs
 Infections
1
33
FACTORS FOR SELECTION OF TREATMENT
 Age: childhood, adolescence, young adult hood,
middle age,>60 yrs
 Type of psoriasis: Plague, palmar, generalised
pustular, etc
 Site and extent of involvement: localised to scalp,
palms, scattered plaques but <5% involvement:
generalised and >30% involement.
 Previous treatment: Systemic glucocorticoids,
methotrexate
 Associated medical disorders(eg. HIV, CVD)
 Duration of Disease: <1month, <1 yr, >1yr
34
PROTOCOL-1
 Mild symptoms
 Recent origin
 Localized
35
CHIKITSA
 Sadya Virechana with Avipatti choornam-20gms for
1day
 if saama lakshanas are seen - Shaddharana(5gm) /
panchakola choorna)
 Mahatiktakam kashaya - 15ml bd for 1st week
 Kaisoraguggulu - 1 tab bd for first week
 Manasamitra vataka - 1 tab bd for 2 weeks
 Gandhaka rasayan - 100mg with honey bd
(throughout)
 Vitpala kera taila - external application followed by
sun exposure
36
PROTOCOL 2
 MODERATE SYMPTOMS
 HISTORY OF 2-6 MONTHS
 AFFLICTED TO A LARGER AREA
37
CHIKITSA
 Mahatiktakam ghrutha -15 gm(inc acc to agni bala X 7 days for
snehan (along with Abhyangam and sarvanga swedanam)
 SadyoVirechana with Avipatti choorna - 20gm for 1st week.
 Tiktakam kashaya - 15ml bd X 2 weeks
 ( if saama lakshanas are seen - 5-6gm shaddharana choorna
/gutika)
 Kaishore Guggulu - 1 tab tds X 2 weeks
 Arogya vardhini gutika - 1 tab tds X 2weeks
 Gandhaka Rasayan- 100mg with honey (throughout)
 Haridrakhandam -12gm bd X 2weeks
 Manasmitra vatakam – 2 tabs bd X 2weeks
 Vitpala kera taila - external application followed by sun exposure
38
EXTERNAL TREATMENTS
 Vitpala kera taila
 Vitpala snana/Sidharthaka snana choorna
 Takra dhaara (musta,amalaki)
39
PROTOCOL 3
 SEVERE SYMPTOMS
 HISTORY OF 6 MONTHS AND MORE
 SPREAD EXTENSIVE AREAS
 WITH SEVERE MENTAL STRESS
40
CHIKITSA
 Starting with the previous protocol according to the bala,
avastha of Roga and Rogi, moving on to the additional
treatments.
 Rookshana – Takra dhaara(musta,triphala,aragwadhadi)
 Deepana-pachana -Panchakola churna with takra/usna
jala
 Snehapana -dose acc. to agni bala. (Mahatiktakam
ghrutha/guggulutiktakam ghruta)
 Abhyangam - vitpala
 Swedana - usna jala snana, atapa sevan
 Nasya - shadbindu taila
 Vamana - madana,vacha,yashti,pippali+madhu
 Virechana - avipatti choorna/ trivrut leha
41
FOLLOW UP
Need of Rasa-Rakta prasadana - Manobala
vardhaka -Rasayana chikitsa. Rasa-Rakta
parasadana
 Mahamanjishtadi kashaya. 15ml bd X 1
month
 Krumimudgar ras 1 hs X 1week
 Manasamitra vataka 1bd X 1 month
 Kalayana ghrutha 12gm hs X 1month
 Gandhaka Rasayana 1tab bd X 1month
42
PATHYA
 For a minimum of 3 months to control symptoms
and relapse
 Ahara :Avoid Virudha, vidaahi , guru , abhishyandi,
navaanna, matsya, anupa mamsa, kanda varga. :
reduce the use of lavana : include more haridra,
rasona, pepper in the diet. : avoid pickles, dadhi at
night ,fermented food items. : avoid bakery items
(maida), oily and spicy foods. : strictly avoid egg,beef
and pork. : Avoid ready to cook items, tinned foods
etc. : avoid re-cooking refrigerated foods.
 Vihaara : maintain hygiene in all aspects. : practice
Achara rasayana.
43
MANAGEMENT OF PSORIASIS: SUMMARY
 Chronic, inflammatory disease of skin
 Classic presentation characterised by
red, scaly plaques
 Management should address both
medical and psychological aspects
 Treatments include externaltherapy,
panchkarma, Rasa-Rakta prasadana -
Manobala vardhaka -Rasayana chikitsa.
Rasa-Rakta parasadana
44
THANK
YOU
ALL
45

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Psoriasis management of ayurveda

  • 1. PSORIASIS – AYURVEDIC MANAGEMENT Vaidya Ruchi Gulati, MD(Ayu) SukhAyurveda 1
  • 2. OVERVIEW 5. Summary 2 4. Managing psoriasis 3. Diagnosing psoriasis 2. Clinical presentation 1. Introduction
  • 3. WHAT IS PSORIASIS?  Inflammatory and hyperplastic disease of skin  Characterised by erythema and elevated scaly plaques  Chronic, relapsing condition  Course of disease often unpredictable 3
  • 5. EPIDEMIOLOGY  Common skin disorder  Prevalence variable: ~ 0.3–2.5%  Prevalence equal in males and females  Estimated incidence: ~ 60 per 100,000 per year 5
  • 6. AGE OF ONSET  Mean age: ~ 23–37 years  Current theory: 2 distinct peaks with possible genetic associations  Early onset (16–22 years)  More severe and extensive  More likely to have affected first-degree family member  Late onset (57–60 years)  Milder form  Affected first-degree family members nearly absent 6
  • 7. PSORIASIS IS A T-CELL MEDIATED, AUTOIMMUNE DISEASE1 Current hypothesis:  Unknown skin antigens stimulate immune response  Antigen-specific memory T-cells are primary mediators  Leads to impaired differentiation and hyperproliferation of keratinocytes 7
  • 8. COMMON TRIGGER FACTORS FOR PSORIASIS  Infections (e.g. streptococcal, viral)  Skin trauma (Koebner phenomenon)  Psychological stress  Drugs (e.g. lithium, beta blockers)  Sunburn  Metabolic factors (e.g. calcium deficiency)  Hormonal factors (e.g. pregnancy) 8
  • 10. CLINICAL PRESENTATION: CLASSIC PSORIASIS  Well-defined and sharply demarcated  Round/oval- shaped lesions  Usually symmetrical  Erythematous, raised plaques  Covered by white, silvery scales 10
  • 11. COMMON SITES AFFECTED BY PSORIASIS  Can affect any part of the body – typically scalp, elbow, knees and sacrum  Extent of disease varies 1 11
  • 13. TYPES OF PSORIASIS  Chronic plaque  Guttate  Flexural  Erythrodermic  Pustular  Localised and generalised  Local forms  Palmoplantar  Scalp  Nail (psoriatic onychodystrophy) 13
  • 14. CHRONIC PLAQUE PSORIASIS  Most common type – affects approximately 85%  Features pink, well- defined plaques with silvery scale  Lesions may be single or numerous  Plaques may involve large areas of skin  Classically affects elbows, knees, buttocks and scalp 14
  • 19. GUTTATE PSORIASIS  Numerous and small lesions – ~ 1 cm diameter  Pink with less scale than plaque psoriasis  Commonly found on trunk and proximal limbs  Typically seen in individuals < 30 years  Often preceded by an upper respiratory tract streptococcal infection 1. 19
  • 20. FLEXURAL PSORIASIS  Lesions in skin folds articularly groin, gluteal cleft, axillae and submammary regions  Often minimal or absent scaling  May cause diagnostic difficulty when genital or perianal region is affected in isolation 1 20
  • 21. ERYTHRODERMIC PSORIASIS  Generalised erythema covering entire skin surface  May evolve slowly from chronic plaque psoriasis or appear as eruptive phenomenon  Patients may become febrile, hypo/hyperthermic and dehydrated  Complications include cardiac failure, infections, malabsorption and anaemia  Relatively uncommon 21
  • 22. PUSTULAR PSORIASIS  Two forms:  Localised form  More common  Presents as deep-seated lesions with multiple small pustules on palms and soles  Generalised form  Uncommo Associated with fever and widespread pustules across the body  inflamed body surface 22
  • 23. PALMOPLANTAR PSORIASIS  Can be hyperkeratotic or pustular  May mimic dermatitis – look for psoriatic manifestations elsewhere to aid diagnosis  Possibly aggravated by trauma 23
  • 24. SCALP PSORIASIS  Varies from minor scaling with erythema to thick hyperkeratotic plaques  May extend beyond hairline  Patient scratching may produce asymmetric plaques 24
  • 25. NAIL PSORIASIS  May be present in patients with any type of psoriasis  Can take several forms:  Pitting: discrete, well- circumscribed depressions on nail surface  Subungual hyperkeratosis: silvery white crusting under free edge of nail with some thickening of nail plate  Onycholysis: nail separates from nail bed at free edge  ‘Oil-drop sign’: pink/red colour change on nail surface 25
  • 27. PSORIATIC ARTHRITIS  Approximately 5–20% have associated arthritis  Five major patterns of psoriatic arthritis:  Distal interphalangeal involvement  Symmetrical polyarthritis  Psoriatic spondylarthropathy  Arthritis mutilans  Oligoarticular, asymmetrical arthritis  Clinical expressions often overlap 27
  • 28. DIAGNOSING PSORIASIS  Other dermatological disorders can resemble psoriasis  Diagnosed clinically according to appearance, distribution, history of lesions and family history  Important to consider non-cutaneous complications 28
  • 29. DIFFERENTIAL DIAGNOSIS  Localised patches/plaques  Tinea  Eczema  Superficial basal cell carcinoma and Bowen’s disease  Seborrhoeic dermatitis  Cutaneous T-cell lymphoma (mycosis fungoides)  Guttate  Pityriasis rosea  Drug eruption  Secondary syphilis  Flexural  Tinea  Eczema  Candidiasis  Seborrhoeic dermatitis  Erythrodermic  Eczema  Cutaneous T-cell lymphoma  Pityriasis rubra pilaris  Lichen planus  Drug  Palmoplantar  Tinea 29
  • 30. CLINICAL APPROACH  Dosha chikitsa -Vatakapha/kapha/vata/pitta  Dushya chikitsa -Rasa, Rakta Prasadana  Avasthanusara Chikitsa -Saama/Niraama -Navina/ Jirna  Vyadhi pratyaneeka chikitsa  Manobala vardhaka chikitsa  Rasayana(Naimittika) 30
  • 31. MANAGING PSORIASIS  Goals of management  Tailor management to individual and address both medical and psychological aspects  Improve quality of life  Achieve long-term remission and disease control  Minimise drug toxicity  Evaluate and monitor efficacy and suitability of individual treatments  Remain flexible and respond to changing needs 31
  • 32. MANAGING PSORIASIS  Before starting treatment  Establish relationship of trust with patient  Provide patient with information  Emphasise benign nature of disease  Explain that psoriasis tends to be chronic and recurrent 32
  • 33. TREATING PSORIASIS: GENERAL MEASURES  Reduce/eliminate potential trigger factors:  Stress  Smoking  Alcohol  Trauma  Drugs  Infections 1 33
  • 34. FACTORS FOR SELECTION OF TREATMENT  Age: childhood, adolescence, young adult hood, middle age,>60 yrs  Type of psoriasis: Plague, palmar, generalised pustular, etc  Site and extent of involvement: localised to scalp, palms, scattered plaques but <5% involvement: generalised and >30% involement.  Previous treatment: Systemic glucocorticoids, methotrexate  Associated medical disorders(eg. HIV, CVD)  Duration of Disease: <1month, <1 yr, >1yr 34
  • 35. PROTOCOL-1  Mild symptoms  Recent origin  Localized 35
  • 36. CHIKITSA  Sadya Virechana with Avipatti choornam-20gms for 1day  if saama lakshanas are seen - Shaddharana(5gm) / panchakola choorna)  Mahatiktakam kashaya - 15ml bd for 1st week  Kaisoraguggulu - 1 tab bd for first week  Manasamitra vataka - 1 tab bd for 2 weeks  Gandhaka rasayan - 100mg with honey bd (throughout)  Vitpala kera taila - external application followed by sun exposure 36
  • 37. PROTOCOL 2  MODERATE SYMPTOMS  HISTORY OF 2-6 MONTHS  AFFLICTED TO A LARGER AREA 37
  • 38. CHIKITSA  Mahatiktakam ghrutha -15 gm(inc acc to agni bala X 7 days for snehan (along with Abhyangam and sarvanga swedanam)  SadyoVirechana with Avipatti choorna - 20gm for 1st week.  Tiktakam kashaya - 15ml bd X 2 weeks  ( if saama lakshanas are seen - 5-6gm shaddharana choorna /gutika)  Kaishore Guggulu - 1 tab tds X 2 weeks  Arogya vardhini gutika - 1 tab tds X 2weeks  Gandhaka Rasayan- 100mg with honey (throughout)  Haridrakhandam -12gm bd X 2weeks  Manasmitra vatakam – 2 tabs bd X 2weeks  Vitpala kera taila - external application followed by sun exposure 38
  • 39. EXTERNAL TREATMENTS  Vitpala kera taila  Vitpala snana/Sidharthaka snana choorna  Takra dhaara (musta,amalaki) 39
  • 40. PROTOCOL 3  SEVERE SYMPTOMS  HISTORY OF 6 MONTHS AND MORE  SPREAD EXTENSIVE AREAS  WITH SEVERE MENTAL STRESS 40
  • 41. CHIKITSA  Starting with the previous protocol according to the bala, avastha of Roga and Rogi, moving on to the additional treatments.  Rookshana – Takra dhaara(musta,triphala,aragwadhadi)  Deepana-pachana -Panchakola churna with takra/usna jala  Snehapana -dose acc. to agni bala. (Mahatiktakam ghrutha/guggulutiktakam ghruta)  Abhyangam - vitpala  Swedana - usna jala snana, atapa sevan  Nasya - shadbindu taila  Vamana - madana,vacha,yashti,pippali+madhu  Virechana - avipatti choorna/ trivrut leha 41
  • 42. FOLLOW UP Need of Rasa-Rakta prasadana - Manobala vardhaka -Rasayana chikitsa. Rasa-Rakta parasadana  Mahamanjishtadi kashaya. 15ml bd X 1 month  Krumimudgar ras 1 hs X 1week  Manasamitra vataka 1bd X 1 month  Kalayana ghrutha 12gm hs X 1month  Gandhaka Rasayana 1tab bd X 1month 42
  • 43. PATHYA  For a minimum of 3 months to control symptoms and relapse  Ahara :Avoid Virudha, vidaahi , guru , abhishyandi, navaanna, matsya, anupa mamsa, kanda varga. : reduce the use of lavana : include more haridra, rasona, pepper in the diet. : avoid pickles, dadhi at night ,fermented food items. : avoid bakery items (maida), oily and spicy foods. : strictly avoid egg,beef and pork. : Avoid ready to cook items, tinned foods etc. : avoid re-cooking refrigerated foods.  Vihaara : maintain hygiene in all aspects. : practice Achara rasayana. 43
  • 44. MANAGEMENT OF PSORIASIS: SUMMARY  Chronic, inflammatory disease of skin  Classic presentation characterised by red, scaly plaques  Management should address both medical and psychological aspects  Treatments include externaltherapy, panchkarma, Rasa-Rakta prasadana - Manobala vardhaka -Rasayana chikitsa. Rasa-Rakta parasadana 44