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Sumukti syrup

Sumukti syrup Introduction
Ingredients
Raspanchaka
Sumukti Syp. As a whole
Doses and Anupana
Research works done

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Sumukti syrup

  1. 1. SUMUKTI SYRUP PRESENTED BY DR PRABHAKAR MANU 2ND YEAR PG SCHOLAR DEPT. OF MANASA ROGA SDM COLLEGE OF AYURVEDA & HOSPITAL, HASSAN
  2. 2. CONTENTS • INTRODUCTION • INGREDIENTS • RASPANCHAKA • SUMUKTI SYP. AS A WHOLE • DOSES AND ANUPANA • RESEARCH WORKS DONE
  3. 3. INTRODUCTION •Popular & Anubhoota Yoga of SDMCAH, Hassan •Hepatoprotective in action •Widely used in De-addiction program
  4. 4. INGREDIENTS 1. Guduchi 2. Bringaraja 3. Kirata Tiktha 4. Amalaki 5. Hareetaki 6. Vibhitaki 7. Draksha 8. Sugar 9. Mandukaparni 10.Aswagandha 11.Yashtimadhu 12.Katuki
  5. 5. Sl No Sanskrit name Latin Name Part Used Quantity in gms 1. Aswangandha Withania somnifera Root 400 2. Hareetaki Terminalia chebula Fruit 400 3. Vibhitaki Terminalia bellerica Fruit 400 4. Amalaki Emblica offinalis Fruit 400 5. Yashtimadhu Glycyrrihiza glabra Stem, Root 400
  6. 6. 6. Mandukaparni Centrella asiatica W P 100 7. Guduchi Tinospora cordifolia Stem 400 8. Kiratatikhta Swertia chirata W P 800 9. Katuki Pichrorhiza kurroa Rhi 800 10 . Draksha Vitis venefera Fruit 3200 11 . Bringaraja Weddalia calendulaca W P 400
  7. 7. 15 Sodium benzoate .5% 16 sugar 50kg
  8. 8. Sl No Sanskrit name Ra Gu Vip Vee 1. Aswangandha Ti, Kas La M S 2. Hareetaki M,A,Kat,Kas,Ti La, Ru M U 3. Vibhitaki Kas La, Ru M U 4. Amalaki M,A,Kat,Kas,Ti La, Ru M S 5. Yashtimadhu M G, Sn M S 6. Mandukaparni M,Kat,Kas,Ti La, Sa M S 7. Guduchi Ti, Kas La M U 8. Kiratatikhta T La, Ru K S 9. Katuki Kat,T La K U 10. Draksha M, Kas G, Sn M S 11. Bringaraja Kat,T Ru, Ti K U
  9. 9. Sanskrit name KARMA Aswangandha Rasayana, Vatakaphahara, Balya Hareetaki Deepana,Tridoshahara, Rasayana Vibhitaki Kaphapittahara, Bhedaka, Krimihara Amalaki Rasayana, Tridoshahara, Cakushya,Raktaprasadana Yashtimadhu Balya, Rakthaprasadana, VP hara Mandukaparni Balya,Vishahara,Medhya,Rasayana Guduchi Deepana, Rasayana,VPK, Rakthashodaka Kiratatikta Rakthashodhaka, KP hara Katuki Pittahara, Deepana, Hrudya Draksha Bruhmana, VP hara, Vrushya
  10. 10. SUMUKTI SYP. AS A WHOLE • Rasa- Tiktha, Kashaya • Guna- Laghu, Ruksha • Vipaka- Madhura • Veerya- Sita • Karma- Tridosha, Balya, Rasayana, Vishagna, Rakthaprasadana, Rakthashodaka, Medhya
  11. 11. DOSE • 2 – 4 teaspoon twice a day after food • Anupana - water
  12. 12. RESEARCH WORKS DONE • A CLINICAL STUDY ON THE EFFICACY OF “SUMUKTI”-AN INDEGINOUS COMPOUND ON MADATYAYA W.S.R TO ALCOHOL DEPENDENCE By Dr. UNNIKRISHNAN P. M Under The Guidance of DR. SAVITHA H.P, MD(Ayu) Associate Professor Department of Manasa Roga
  13. 13. •Effect on subjective parameters •Effect of sumukti on craving: •30 patients shown craving in a mean of 8.13 which is reduced to 2.96 after treatment and 63.59% of improvement •Effect of sumukti on tolerance: •Mean score of tolerance was 6.36 before treatment which came down to 1.36 after treatment. It shown 78.61% of improvement
  14. 14. •Effect of sumukti on salience: •Symptom salience had a mean score of 6.13 before treatment and it came down to 2.16 after treatment. It shown 64.76% of improvement •Effect of sumukti on loss of control: •6.70 was the mean score of symptom loss of control before treatment which came down to 1.9 after completion of one month treatment.
  15. 15. •Effect on objective parameters •Effect of sumukti on liver function test •Effect on total bilirubin: •Before treatment means score of total bilirubin was 1.35 which came down to 0.94 with 30.37% of improvement. •Effect on direct bilirubin: •Before treatment mean score of direct bilirubin was 0.85 which came down to 0.58 with 31.76% of improvement.
  16. 16. •Effect on indirect bilirubin: •Before treatment mean score of indirect bilirubin was 0.50 which came down to 0.36 with 28% of improvement. •Effect on aspartate aminotransferase [ SGOT]: •Before treatment mean score of SGOT was 89.95 which came down to 30.06 with 66.58% of improvement.
  17. 17. • Effect of sumukti on persistent use: • Persistent use showed a mean score of 7.13 before treatment and it came down to 1.73 after completion of treatment. It showed 75.73% of improvement • Effect of sumukti on withdrawal symptoms: • In withdrawal symptoms 5.2 was the mean score before treatment which came down to 1.26 after treatment. It showed 75.76% improvement
  18. 18. • Effect on alanine aminotransferase [SGPT]: • Before treatment mean score of SGPT was 74.74 which came down to 27.01 with 63.86% of improvement. • Effect on USG abdomen: • Mean value of USG abdomen was 1.33 before treatment and it came down to 0.00 after treatment.
  19. 19. ACTIVE INGREDIENTS • Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis • T. chebula, T. belerica and E. officinalis fruits, through their measurement of activities in scavenging of different free radicals including hydroxyl, superoxide, nitric oxide, hydrogen peroxide, peroxynitrite, singlet oxygen, hypochlorous acid, phenol, flavonoid and ascorbic acid content and total antioxidant activity
  20. 20. • Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin • Other in vivo and clinical studies have reported beneficial effects of both licorice and glycyrrhizin consumption including anti-ulcer, anti-viral, and hepatoprotective responses. • Tinosporia cordifolia has hepato protective activity,And has antioxident activity.
  21. 21. POTENT HERBAL HEPATOPROTECTIVE DRUGS- A REVIEW SWERTIA CHIRATA Amarogentin, Gentiopicrin ,Gentianine, Drug also possesses digestive, hepatic (conditions pertaining to the liver), tonic, astringent and appetizer properties and used in cough, dropsy and skin diseases. Eclipta Alba (Bhringaraj)- The hepatoprotective effect of the ethanol/water (1:1) extract of Eclipta Alba (Asteraceae) was studied at subcellular levels in rats against (CCl4) -induced hepatotoxicity. The loss of hepatic lysomal acid phosphatase and alkaline phosphatase by (CCl4) was significantly restored by Eclipta Alba.
  22. 22. • Picrorhiza kurroa (Kutki) • The increased levels of serum glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), alkaline phosphatase, lipoprotein-X (LP-X) and bilirubin in the infected animals were marked reduced by different doses of picroliv.
  23. 23. DISPENSARY PACKAGING
  24. 24. Discussion and conclusion • One of the important yoga acting as Hepatoprotective action • All ingredients have tikta rasa converted into syrup base with added sugar to avoid patient compliance and to make more palatable • Majority of ingredients have antioxidant activity
  25. 25. Thank you……….

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